Chondromyxoid fibroma involving the sphenoid sinus: Case report and literature review.

We present the case of a 62-year-old woman with chondromyxoid fibroma of the sphenoid sinus. Chondromyxoid fibroma is a rare bone tumor found most prevalently in long bones, so its presence at the cranial base is especially uncommon. The presence of a monoclonal gammopathy of undermined significance (MGUS) prompted consideration and investigation of a plasma cell disorder; however, CT and MRI findings followed by biopsy led to the correct diagnosis of chondromyxoid fibroma.

Conspicuity of microcalcifications on digital screening mammograms using varying degrees of monitor zooming.

RATIONALE AND OBJECTIVES: American College of Radiology guidelines suggest that digital screening mammographic images should be viewed at the full resolution at which they were acquired. This slows interpretation speed. The aim of this study was to examine the effect of various levels of zooming on the detection and conspicuity of microcalcifications. MATERIALS AND METHODS: Six radiologists viewed 40 mammographic images five times in different random orders using five different levels of zooming: full resolution (100%) and 30%, 61%, 88%, and 126% of that size. Thirty-three images contained microcalcifications varying in subtlety, all associated with breast cancer. The clusters were circled. Seven images contained no malignant calcifications but also had randomly placed circles. The radiologists graded the presence or absence and visual conspicuity of any calcifications compared to calcifications in a reference image. They also counted the microcalcifications. RESULTS: The radiologists saw the microcalcifications in 94% of the images at 30% size and in either 99% or 100% of the other tested levels of zooming. Conspicuity ratings were worst for the 30% size and fairly similar for the others. Using the 30% size, two radiologists failed to see the microcalcifications on either the craniocaudal or mediolateral oblique view taken from one patient. Interobserver agreement regarding the number of calcifications was lowest for the 30% images and second lowest for the 100% images. CONCLUSIONS: Images at 30% size should not be relied on alone for systematic scanning for microcalcifications. The other four levels of magnification all performed well enough to warrant further testing.

Thyroid abscess: case report and review of the literature.

A thyroid abscess is an infrequently encountered condition with a rarity that is attributable to anatomic and physiologic characteristics of the gland that impart a unique quality of infection resistance. The differential diagnoses for a painful thyroid is limited, with subacute and chronic thyroiditis being the most often-encountered processes. Acute suppurative thyroiditis with abscess formation, although rare, is a formidable clinical scenario with morbid complications. Because the diagnosis of a thyroid abscess is often delayed in lieu of investigating other more common etiologies of thyroiditis, this disease entity may portend to a dismal clinical outcome. The authors report the case of a 53-year-old woman with a thyroid abscess yielding a single microbial isolate believed to be resultant from a urinary tract bacteremia. They also review the literature for discussion of abscess etiologies, presentations, and management strategies.

Presentation and management of extensive fronto-orbital-ethmoid mucoceles.

OBJECTIVES: The aim of the study was to report the presentation and management of extensive fronto-orbital-ethmoid (FOE) mucoceles. METHODS: This study is a retrospective chart review of 13 consecutive patients requiring surgical intervention for extensive FOE mucoceles. Patients were treated over the period from 1999 to 2003. Variables examined include chief complaint, risk factors, location of erosion, management, and complications. Follow-up ranged from 12 to 36 months. RESULTS: Most common chief complaint was eye proptosis, followed by forehead swelling and orbital cellulitis. Four patients had previous functional endoscopic sinus surgery (FESS) and another 4 patients had history of prior trauma and frontal sinus obliteration. Eleven patients had skull base erosion and 12 had orbital wall erosion. Four patients were managed endoscopically. Of these, 1 had previously undergone FESS, whereas the other 3 had no risk factors. All patients with prior trauma/obliteration were treated with coronal flap and frontal sinus obliteration. One patient who had undergone 2 previous FESS was successfully treated with coronal flap without obliteration. One patient treated with an osteoplastic flap had cerebrospinal fluid leak that was identified and repaired intraoperatively with a pericranial flap. CONCLUSION: Extensive FOE mucoceles can be successfully and safely treated by endoscopic and non-endoscopic methods. The choice of surgical approach mainly depends on the anatomy of the frontal recess. Prior trauma and FESS are associated with requiring coronal flap and frontal sinus obliteration.