Analyzing invariants and employing successive reductions for the extended Kadomtsev Petviashvili equation in (3+1) dimensions.

In this research, we employ the potent technique of Lie group analysis to derive analytical solutions for the (3+1)-extended Kadomtsev-Petviashvili (3D-EKP) equation. The systematic application of this method enables the identification of Lie point symmetries associated with the equation, leading to the derivation of an optimal system of one-dimensional subalgebras relevant to the equation. This optimal system is utilized to obtain several invariant solutions. The Lie group method is subsequently applied to the reduced governing equations derived from the given equation. We complement our findings with Mathematica simulations illustrating some of the obtained solutions. Furthermore, a direct approach is used to investigate local conservation laws. Importantly, our study addresses a gap in the exploration of the 3D-EXP equation using group theoretic methods, making our findings novel in this context.

Expanding the knowledge frontier of mitoviruses in Cannabis sativa.

Mitoviruses were initially known for their presence in the mitochondria of fungi and were considered exclusive to these organisms. However, recent studies have shown that they are also present in a large number of plant species. Despite the potential impact that mitoviruses might have on the mitochondria of plant cells, there is a lack of information about these ancient RNA viruses, especially within the Cannabaceae family. Cannabis sativa has been in the spotlight in recent years due to the growing industrial applications of plant derivatives, such as fiber and secondary metabolites. Given the importance of Cannabis in today's agriculture, our study aimed to expand the knowledge frontier of Mitoviruses in C. sativa by increasing the number of reference genomes of CasaMV1 available in public databases and representing a larger number of crops in countries where its industrial-scale growth is legalized. To achieve this goal, we used transcriptomics to sequence the first mitoviral genomes of Colombian crops and analyzed RNA-seq datasets available in the SRA databank. Additionally, the evolutionary analysis performed using the mitovirus genomes revealed two main lineages of CasaMV1, termed CasaMV1_L1 and CasaMV1_L2. These mitoviral lineages showed strong clustering based on the geographic location of the crops and differential expression intensities.

Disseminated Cutaneous Mycobacterium chelonae Infection in an Immunocompetent Patient.

We present a case report on disseminated cutaneous Mycobacterium chelonae infection with a sporotrichoid pattern in an immunocompetent patient. The aim of this report is to contribute to the existing knowledge on the clinical presentation and management of this uncommon presentation.

Combining the Peptide RWQWRWQWR and an Ethanolic Extract of Bidens pilosa Enhances the Activity against Sensitive and Resistant Candida albicans and C. auris Strains.

The antifungal activity of palindromic peptide RWQWRWQWR and its derivatives was evaluated against clinical isolates of Candida albicans and C. auris. Also, Bidens pilosa ethanolic extracts of leaves and stem were evaluated. Furthermore, combinations of peptide, extract, and/or fluconazole (FLC) were evaluated. The cytotoxicity of peptides and extracts in erythrocytes and fibroblasts was determined. The original palindromic peptide, some derivative peptides, and the ethanolic extract of leaves of B. pilosa exhibited the highest activity in some of the strains evaluated. Synergy was obtained between the peptide and the FLC against C. auris 435. The combination of the extract and the original palindromic peptide against C. albicans SC5314, C. auris 435, and C. auris 537 decreased the minimal inhibitory concentrations (MICs) by a factor of between 4 and 16. These mixtures induced changes in cell morphology, such as deformations on the cell surface. The results suggest that the combination of RWQWRWQWR and B. pilosa extract is an alternative for enhancing antifungal activity and decreasing cytotoxicity and costs and should be considered to be a promising strategy for treating diseases caused by Candida spp.

Características, estacionalidad y tendencia de las hospitalizaciones por enfermedad de Kawasaki en niños de Perú, 2015-2019

Introducción: Existen limitados reportes epidemiológicos de la enfermedad de Kawasaki (EK) en Latinoamérica. Objetivo: Describir las características, estacionalidad y tendencia de las hospitalizaciones por EK en niños. Métodos: Se realizó un estudio descriptivo de análisis secundario con datos de hospitalizaciones por EK de instituciones de salud de Perú en el periodo 2015-2019. Resultados: 297 hospitalizaciones fueron registradas. El 59,9% fueron varones. El 82,2% fue menor de cinco años y el 16,2% menor de un año. Los departamentos con más hospitalizaciones fueron Lima, Lambayeque y Piura con 202, 21 y 17 casos. Las estaciones con mayor registro fueron invierno y primavera. La incidencia de EK se incrementó de 0,52 a 2,28 casos/100 000 niños menores de cinco años entre el 2015 al 2019. Conclusiones: Hubo un incremento de las hospitalizaciones por EK, este fue más frecuente en niños menores de cinco años, varones y se presentó en todas las estaciones.

Introduction: There are limited epidemiological reports of Kawasaki disease (KD) in Latin America. Objetive: To describe the characteristics, seasonality, and trend of hospitalizations for KD in children. Methods: Descriptive study of secondary analysis was performed with data on hospitalizations due to KD from healthcare institutions from Peru, 2015-2019. Results: Two hundred ninety-seven hospitalizations were registered. 59.9% were male. 82.2% were under five years old, and 16.2% were under one year old. The departments with more hospitalizations were Lima (202 cases), Lambayeque (21 cases), and Piura (17 cases). The seasons of the year with more hospitalizations were winter and spring. The incidence of KD increased from 0.52 to 2.28 cases per 100,000 children under five years old between 2015 and 2019. Conclusions: There was an increase in hospitalizations due to KD, this was more frequent in children under five years of age and males, and it occurred in all seasons.

Giant Nevus Lipomatosus Cutaneous Superficialis in the Vulva: Finding the Best Treatment.

This report presents a rare case of a giant Nevus Lipomatosus Cutaneous Superficialis (NLCS) on the vulva of a 38-year-old female. The patient underwent excisional surgery and electrodesiccation for complete lesion removal. Recurrence following CO2 laser treatment was observed. The study highlights the challenges in managing large NLCS lesions in challenging locations and emphasizes the importance of combining surgical excision and electrodesiccation for successful treatment. Further research and reported cases are needed to enhance our understanding of this rare condition and guide optimal treatment strategies.

Estrés y espiritualidad relacionado con la sobrecarga en cuidadores de adultos mayores con dependencia total / Stress and Spirituality Related to Overload in Caregivers of Totally Dependent Older Adults

Introducción: La población adulta mayor requiere atención por los cambios del envejecimiento, la atención que los cuidadores otorgan al adulto mayor dependiente suele generar estrés; los cuidadores recurren a la espiritualidad para afrontar la sobrecarga y estresores del cuidado. Objetivo: Relacionar el estrés y la espiritualidad con la sobrecarga en cuidadores de adultos mayores con dependencia total. Métodos: Se realizó un estudio descriptivo y correlacional en una población de cuidadores de adultos mayores de un centro comunitario de jurisdicción sanitaria en Heroica Matamoros, Tamaulipas, México, entre enero y julio del 2021. Muestra de 75 participantes para una población infinita, se aplicó muestreo por conveniencia. Se aplicó una cédula de datos personales, la Escala de Estrés Percibido, el Cuestionario de Espiritualidad y la Escala de Zarit. Los datos se analizaron en el paquete estadístico SPSS versión-21, se utilizó estadística descriptiva y se realizó correlación de Spearman. Resultados: El 56 por ciento de los cuidadores son hijos o hijas del adulto mayor dependiente, en promedio tuvieron 5,21 (DE= 3,68) horas al día dedicadas al cuidado y 7,67 (DE= 2,28) meses. Se encontró relación entre el estrés y la sobrecarga del cuidador (rs= 0,462; p= 0,000), no hubo relación entre la espiritualidad global y la sobrecarga del cuidador (rs= -0,169; p= 0,147). Conclusiones: A pesar de que la relación entre la espiritualidad global y la sobrecarga del cuidador no fue significativa, se observó relación entre el estrés y sobrecarga del cuidador(AU)

Introduction: The older adult population requires attention because of the changes as a result of aging. The caregivers' attention provided to dependent older adults often produces stress. Caregivers turn to spirituality to cope with the overload and stressors of caregiving. Objective: To relate stress and spirituality with overload in caregivers of totally dependent older adults. Methods: A descriptive and correlational study was conducted with a population of caregivers of older adults from a community health jurisdiction center in Heroica Matamoros, Tamaulipas, Mexico, between January and July 2021. Through convenience sampling, 75 participants made up a sample obtained as an infinite population. A personal data questionnaire, the Perceived Stress Scale, the Spirituality Questionnaire and the Zarit scale were applied. The data were analyzed using the statistical package SPSS (version 21), descriptive statistics were used and Spearman's correlation was performed. Results: 56 percent of the caregivers were children to dependent older adults, who were, on average, 5.21 (SD = 3.68) daily hours or 7.67 (SD = 2.28) months dedicated to caregiving. A relationship was found between stress and caregiver overload (rs= 0.462; p= 0.000). There was no relationship between overall spirituality and caregiver overload (rs= -0.169; p= 0.147). Conclusions: Although the relationship between overall spirituality and caregiver overload was not significant, there was a relationship between stress and caregiver overload(AU)

Validez de contenido de una intervención educativa para mejorar conocimientos, actitudes y prácticas relacionados con la malaria en una comunidad indígena / Content validity of an educational intervention to improve knowledge, attitudes and practices related to malaria in an indigenous community / Validade de conteúdo de uma intervenção educativa para melhorar conhecimentos, atitudes e práticas relacionadas à malária em uma comunidade indígena

Introducción: Las intervenciones educativas en salud dirigidas a las poblaciones indígenas deben ser revisadas por expertos con el fin de evaluar si su adaptación cultural es apropiada y precisa. Objetivo: Determinar la validez de los contenidos contemplados en una intervención educativa para el mejoramiento de conocimientos, actitudes y prácticas relacionados con la malaria en la población Emberá Katío del departamento de Córdoba - Colombia, mediante el juicio de expertos. Materiales y métodos: Estudio de validación por medio de juicio de expertos de una intervención educativa que incluyó cuatro módulos, administrados en sesiones presenciales, en las que se utilizaron estrategias educativas como clases, discusiones guiadas y talleres. Participaron trece expertos en trabajo con comunidades indígenas, quienes evaluaron los criterios de claridad, pertinencia, relevancia y coherencia del contenido de cada módulo. Se estimó el índice de validez de contenido (IVC) de Lawshe modificado por Tristán y se asumió el valor ≥ 0.58 para considerar la aprobación de los criterios de los módulos. Resultados: Todos los módulos obtuvieron IVC globales que fluctuaron entre 0.83 y 0.90. La claridad del Módulo 1, 'Conociendo la malaria', tuvo un valor de 0.69 y el resto de los valores de los cuatro criterios osciló entre 0.77 y 1. Discusión: Los criterios evaluados superaron el punto de corte establecido por la literatura para aprobar la intervención, y las observaciones y recomendaciones de los expertos fueron consideradas para ajustes en la misma. Conclusión: Se determina que la intervención educativa evaluada por juicio de expertos, tiene alta validez de contenido en sus módulos según los criterios contrastados.

Introduction: Health education programs for the indigenous population must be reviewed by experts in order to assess whether their cultural adaptation is appropriate and accurate. Objective: To determine the validity of the content contemplated in an educational intervention to improve knowledge, attitudes and practices related to malaria in the Emberá Katío population in the department of Córdoba, Colombia. Materials and methods: Validation study by experts' judgment of an educational intervention that included four modules, administered in face-to-face sessions, in which educational strategies such as classes, guided discussions and workshops were used. Thirteen experts in work with indigenous communities participated, who evaluated the criteria of clarity, pertinence, relevance and coherence of the content of each module. The content validity index (CVI) of Lawshe modified by Tristán was estimated and the value ≥ 0.58 was assumed to consider the approval of the module criteria. Results: All the modules obtained global CVIs fluctuated between 0.83 and 0.90. The clarity of Module 1, 'Knowing malaria', had a value of 0.69 and the rest of the values of the four criteria ranged between 0.77 and 1. Discussion: The evaluated criteria exceeded the cut-off point established by the literature to approve the intervention, and the observations and recommendations of the experts were considered for adjustments in it. Conclusion: It is determined that the educational intervention evaluated by expert judgment has high content validity in its modules according to the contrasted criteria.

Introdução: As intervenções de educação em saúde voltadas para populações indígenas devem ser revisadas por especialistas a fim de avaliar se sua adaptação cultural é apropriada e precisa. Objetivo: Determinar a validade do conteúdo de uma intervenção educacional para a melhoria do conhecimento, das atitudes e das práticas relacionadas à malária na população Emberá Katío, no departamento de Córdoba - Colômbia, por meio do julgamento de especialistas. Materiais e métodos Estudo de validação por meio de julgamento de especialistas de uma intervenção educacional que incluiu quatro módulos, administrados em sessões presenciais, nos quais foram utilizadas estratégias educativas como aulas, orientadas e oficinas. Participaram treze especialistas em trabalhos com comunidades indígenas, que avaliaram os critérios de clareza, pertinência, relevância e coerência do conteúdo de cada módulo. Estimou-se o índice de validade de conteúdo (IVC) de Lawshe modificado por Tristán e assumiu-se o valor ≥ 0,58 para considerar a aprovação dos critérios do módulo. Resultados: Todos os módulos obtiveram IVC global que oscilou entre 0,83 e 0,90. A clareza do Módulo 1, 'Conhecendo a malária', tinha um valor de 0,69 e os demais valores dos quatro critérios variaram entre 0,77 e 1. Discussão: Os critérios avaliados excederam o ponto de corte estabelecido pela literatura para aprovar a intervenção, e as observações e recomendações dos peritos foram consideradas para ajustes no mesmo. Conclusão: Foi determinado que a intervenção educacional avaliada por julgamento de especialistas tem alta validade de conteúdo em seus módulos, de acordo com os critérios contrastados.

Envejecimiento exitoso y calidad de vida en personas mayores institucionalizadas del norte de colombia

Objetivo: Determinar relación entre Envejecimiento exitoso y Calidad de vida de personas mayores institucionalizadas. Material y Método: Estudio descriptivo y correlacionai con muestreo intencional; previo consentimiento informado, participaron 14o personas mayores asistentes a un hogar del municipio de Montería, Colombia. Se incluyeron a personas de 6o y más años; sus características sociodemográficas fueron identificadas por una cédula de datos. La Calidad de vida se midió con WHOQOL-bref y el Envejecimiento exitoso con Successful Aging Inventory (SAI). Los datos recolectados por enfermeras/os, se procesaron en SPSS v22 y analizados con estadística descriptiva, normalidad con Kolmogorov Smirnov y corrección de Lilliefors; como no hubo distribución normal, el objetivo se respondió con correlación de Spearman. Resultados: Existe relación negativa y significativa entre Envejecimiento exitoso global (p= ,012), Desempeño funcional (p= ,025) y Proposito y satisfacción con la vida (p= ,012) con la dimensión Social de la Calidad de vida; se observo relación negativa y significativa (p= ,013) entre el Propósito y satisfacción con la vida con la dimensión Ambiental de la Calidad de vida. Conclusiones: la mayoría de las personas mayores presentaron un envejecimiento exitoso y tienen su Calidad de vida global y Percepción de su salud altas. Existe relación negativa y significativa entre Envejecimiento exitoso, Desempeño funcional y Propósito y satisfacción con la dimensión Social de la Calidad de vida; existe relación negativa y significativa entre el Propósito y satisfacción con la vida con la dimensión Ambiental de la calidad de vida. No hay relación entre los puntajes globales de Envejecimiento exitoso y Calidad de vida.

Objective: To determine the relationship between successful aging and quality of life among institutionalized elderly people. Materials and Methods: Descriptive and correlational study using intentional sampling. It was carried out, after prior informed consent, with 140 elderly people who attended a nursing home in the city of Monteria, Northern Colombia. People over 60 years and older were included and their sociodemographic characteristics were recorded in a data sheet. The quality of life was measured with the WHOQOL-bref questionnaire and the Successful aging was measured with the Succesful Aging Inventory (SAI). Data collected by nurses were processed in SPSS v22 and analyzed with descriptive statistics, Kolmogorov-Smirnov test for normality and Lilliefors correction. As there was no normal distribution, the Spearman's correlation was applied. Results: There is a negative and significant relationship between the overall successful aging (p= .012), functional performance (p= .025) and life purpose and satisfaction (p= .012) with the social dimension of quality of life; a negative and significant relationship (p= .013) was also observed between life purpose and satisfaction with the environmental dimension of quality of life. Conclusions: Most of the elderly people showed successful aging and had a high overall quality of life and health perception. There is a negative and significant relationship between successful aging, functional performance, as well as life purpose and satisfaction with the social dimension of quality of life; there is a negative and significant relationship between life purpose and satisfaction with the environmental dimension of quality of life. There is no relationship between the overall scores of successful aging and quality of life.

Objetivo: Determinar a relação entre envelhecimento bem-sucedido e qualidade de vida de pessoas idosas institucionalizadas. Material e Método: Estudo descritivo e correlacional com amostragem intencional. O estudo foi realizado, após consentimento informado prévio, com 140 idosos que frequentaram um asilo na cidade de Montería, no norte da Colômbia. Foram incluídas pessoas de 60 anos ou mais e suas características sociodemográficas foram registradas em uma ficha de dados. A qualidade de vida foi medida com o questionário WHOQOL-bref e o inventário Successful Aging Inventory (SAI) foi usado para medir o envelhecimento bem- sucedido. Os dados coletados pelos enfermeiros e enfermeiras foram processados por meio do programa SPSS versão 22 e analisados com estatísticas descritivas e teste Kolmogorov-Smirnov para normalidade e correção de Lilliefors. Como não houve distribuição normal, foi aplicada a correlação do Spearman. Resultados: Existe uma relação negativa e significativa entre o envelhecimento geral bem-sucedido (p= ,012), desempenho funcional (p= ,025) e propósito de vida e satisfação (p= ,012) com a dimensão social da qualidade de vida; uma relação negativa e significativa (p= ,013) também foi observada entre o propósito de vida e satisfação com a dimensão ambiental da qualidade de vida. Conclusões: A maioria dos idosos demonstrou um envelhecimento bem- sucedido e teve uma alta percepção geral de qualidade de vida e saúde. Há uma relação negativa e significativa entre o envelhecimento bem-sucedido, desempenho funcional, bem como propósito de vida e satisfação com a dimensão social da qualidade de vida; há uma relação negativa e significativa entre proposito de vida e satisfação com a dimensão ambiental da qualidade de vida. Não há relação entre as pontuações gerais do envelhecimento bem-sucedido e a qualidade de vida.

Acquired Immune Deficiency Syndrome Cholangiopathy: Case Series of Three Patients and Literature Review.

Cholangiopathy in acquired immune deficiency syndrome (AIDS) is being less frequently reported since antiretroviral therapy (ART) is available. It is associated with an advanced disease and seen in situations with poor access or non-compliance with ART. Liver biopsy is thought to have low yield in cases of AIDS cholangiopathy, but it can be an important tool in diagnosis, especially early in the course of the disease. The prognosis of AIDS cholangiopathy is generally not favorable, the therapy for opportunistic infections is mostly ineffective and restoration of immune system with ART remains the therapy of choice. We are sharing our experience of diagnosing and managing three cases of AIDS cholangiopathy.

Cardiac atrial masses after a heart transplant. An array of differential diagnoses / Masas auriculares cardíacas tras un trasplante cardíaco. Una serie de diagnósticos diferenciales

Abstract Cardiac masses represent a heterogeneous group, including secondary malignancies as the most common ones, followed by primary tumors, vegetations, and thrombi. Cardiac imaging techniques are essential for the non-invasive diagnosis of cardiac masses. Thrombi in a transplanted heart, especially in atria, are very common, but when they appear as multiple, they could be an early sign of rejection. We present the case of a cardiac transplant patient who presented with masses in both atria and the left ventricle, as well as symptoms of right heart failure. Various image techniques were useful in establishing the differential diagnoses and appropriate treatment.

Resumen Las masas intracardíacas representan un grupo variado, que incluye metástasis como las más frecuentes, seguidas de tumores primarios, vegetaciones y trombos. Los trombos intracavitarios en un paciente trasplantado, especialmente en la aurícula, son muy frecuentes, pero, si aparecen como masas múltiples, pueden ser un dato precoz de un posible rechazo. Se expone el caso de un paciente trasplantado cardíaco que se presenta con masas intracavitarias en ambas aurículas y en el ventrículo izquierdo y datos de insuficiencia cardíaca de predominio derecho. Gracias al uso de varias técnicas de imagen se estableció el diagnóstico diferencial de las mismas, y se instauró el tratamiento adecuado.

[Factors associated with the survival of fetuses with a prenatal diagnosis of megabladder]. / Factores asociados a sobrevida de fetos con diagnóstico prenatal de megavejiga.

The presence of fetal megacystis in a renal ultrasound may suggest a mechanical or functional bladder outlet obstruction, an uncommon condition with a poor outcome. OBJECTIVE: To determine prog nostic factors in fetuses with prenatal diagnosis of megacystis. PATIENTS AND METHOD: Retrospective study carried out between 2003 and 2018 in the Orient Perinatal Reference Center (CERPO), Uni versity of Chile. Prenatal and postnatal data were analyzed, as well as etiology, pulmonary hypoplasia, medical and surgical treatment, mortality, renal function, and need for renal replacement therapy. The primary variable analyzed was survival at one year, and the secondary ones were renal function and predictors of survival. Statistical analysis was performed using the Mann-Whitney U tests or Fisher test, and a p < 0.05 was considered statistically significant. RESULTS: Twenty-five fetuses with prenatal diagnosis of megacystis were included. 52% of them presented oligohydramnios and 84% showed renal anomalies. Vesicocentesis was performed in 15 fetuses and vesicoamniotic shunt was performed in 5 cases. There were 6 intrauterine fetal deaths (24%) and, among the 19 live births, 9 died soon after birth (36%) and 1 died in the post-neonatal period due to a non-nephron-urological cause. Nine newborns survived by one year of age (36%), seven of them with associated nephron- urological anomaly, and two were healthy patients. Two patients developed chronic kidney disease. The presence of pulmonary hypoplasia was the only factor associated with increased perinatal mor tality (p<0.05) secondary to oligohydramnios in all cases. Oligohydramnios was not identified as a prognostic factor in this study. CONCLUSIONS: The prenatal diagnosis of megacystis comprises a wide spectrum of pathologies including conditions with a high perinatal mortality rate to healthy fetuses with transient enlarged bladder without nephron-urological pathology. The only factor associated with increased perinatal mortality was pulmonary hypoplasia.

Las múltiples dimensiones de la salud y enfermedad del ser ecobiopsicosocial en Un monstruo viene a verme (2016) / The multiple dimensions of health and disease of the ecobiopsychosocial being in A monster calls (2016)

Connor O'Malley es un chico de 12 años que padece del síndrome del cuidador debido a la enfermedad terminal de su madre; sus temores se materializan y cobran vida constituyendo de manera fantástica un temible monstruo que tiene como propósito sacar a la luz sus más profundos temores y sentimientos. Todo paciente con enfermedad terminal al dejar de ser independiente requiere atención de cuidadores que aseguren su bienestar y en muchas ocasiones los cuidadores son miembros de la familia. El síndrome del cuidador es una condición provocada por el cuidado extenuante de un familiar dependiente. Este síndrome se manifiesta en respuesta a un estrés emocional y se caracteriza por el agotamiento tanto físico como psicológico. Al constituirse como una entidad ecobiopsicosocial, la salud humana es resultado del bienestar en cada esfera, de modo que, cuando existe afectación de tan solo una de ellas, la salud de un individuo puede afectarse, como sucede en el síndrome del cuidador. El síndrome del cuidador en Connor es el tema del presente artículo, así como lo son los potenciales medios para su abordaje. (AU)

Connor O'Malley is a 12-year-old boy suffering from caregiver syndrome due to his mother's terminal illness; his fears materialize and come to life in a fantastic way constituting a fearsome monster whose purpose is to bring to light his deepest fears and feelings. Every terminally ill patient, when becoming no longer independent, requires care from caregivers who may ensure their well-being, and in many cases the caregivers are family members. Caregiver Syndrome is a condition caused by the strenuous care of a dependent family member. This syndrome manifests in response to emotional stress and is characterized by both physical and psychological exhaustion. By establishing itself as an ecobiopsychosocial entity, human health is the result of well-being in each sphere, so that, when only one of them is affected, the health of an individual can be affected, as occurs in caregiver syndrome. The caregiver syndrome in Connor is the subject of this article, as are the potential means for its approach. (AU)

Benefits of cardiac pacing in ICD recipients with hypertrophic cardiomyopathy.

PURPOSE: Implantable cardiac defibrillator (ICD) is the only definitive therapy for prevention of sudden cardiac death in hypertrophic cardiomyopathy (HCM). Conventional transvenous ICDs can provide cardiac pacing unlike new subcutaneous ICD, but the usefulness of cardiac pacing in HCM patients is not well defined. We sought to assess the usefulness of ICD pacing in HCM. METHODS: We retrospectively analyzed 93 HCM patients who had undergone ICD implantation at our center. Usefulness of pacing was defined as follows: 1) need of pacing due to bradycardia or AV conduction disturbances, 2) improvement of LV outflow tract obstruction by sequential AV pacing, 3) need for CRT pacing, or 4) successful antitachycardia pacing without a subsequent shock. Independent predictors of useful pacing were investigated by multivariable analysis. RESULTS: During a mean follow-up of 91.3 ± 5.5 months, 43 patients (46.2%) reached the composite endpoint. Independent predictors of pacing usefulness were older age (HR 1.36; 95%CI: 1.088-1.709; p=0.007) and NYHA functional class ≥ II (HR 2.15; 95%CI: 1.083-4.301; p=0.029). Twenty-eight (30.1%) patients had appropriate ICD interventions, triggered by a monomorphic ventricular tachycardia (MVT) in 22 of them (78.5%). In 17 individuals with MVT (77%), antitachycardia pacing successfully treated MVT. CONCLUSIONS: In our HCM series of patients with ICD, 46% of individuals benefitted from cardiac pacing. MVT were documented in nearly 80% of the patients with ventricular arrhythmias and antitachycardia pacing successfully treated them in 77% of cases.

¿Cuándo deben operarse los quistes de retención en los senos paranasales? Revisión de la literatura / When should retention cysts in paranasal sinuses be operated? Literature review

Introducción: Los quistes de retención mucoso de los senos paranasales son un hallazgo imagenológico incidental muy frecuente. Usualmente comprometen el seno maxilar. Metodología: Se realizó una amplia búsqueda de la literatura, sobre quistes de retención mucoso nasosinusales, en enero de 2021 en múltiples bases de datos. Se seleccionaron 21 artículos sobre el tema para la realización de la revisión. Discusión: En la mayoría de los casos el tratamiento de los quistes de retención mucoso nasosinusales debe ser expectante debido a su tendencia a la involución y curso asintomático. Sin embargo, en la práctica clínica se observa con frecuencia un manejo quirúrgico sin una indicación clara. Conclusiones: Las indicaciones quirúrgicas de los quistes de retención mucoso son: obstrucción del ostium del seno paranasal, compromiso del complejo ostiomeatal o compromiso del nervio infraorbitario con síntomas secundarios. Es importante que el cirujano reconozca la naturaleza y comportamiento de esta patología para evitar procedimientos quirúrgicos innecesarios.

Introduction: Mucous retention cysts of the paranasal sinuses are a very common incidental imaging finding. They usually involve the maxillary sinus. Methodology: An extensive literature search on nasosinusal mucosal retention cysts was conducted in January 2021 through multiple databases. 21 articles on the subject were included as evidence for this paper. Discussion: In most cases, treatment should be expectant due to its tendency to involution and asymptomatic course. However, in clinical practice, surgical management is frequently observed without a clear indication. Conclusions: Surgical indications for mucosal retention cysts are: obstruction of the sinus ostium, involvement of the ostiomeatal complex, or involvement of the infraorbital nerve with secondary symptoms. It is important for the surgeon to recognize the nature and behavior of this pathology in order to avoid unnecessary surgical procedures.

Funcionamiento familiar y calidad de vida en adultos mayores con hipertensión arterial

RESUMEN Objetivo: Identificar la relación entre el funcionamiento familiar y la calidad de vida en adultos mayores con Hipertensión Arterial. Material y Método: Estudio descriptivo, correlacional y de corte transversal en una población de adultos mayores con hipertensión arterial pertenecientes al centro comunitario las Culturas de la Jurisdicción Sanitaria III en Matamoros, Tamaulipas, México, identificados a través de un muestreo por conveniencia con adultos que acudieron a consulta entre agosto a diciembre de 2019. Se les aplicó el Test de APGAR familiar (Alpha de Cronbach 0,83) y el cuestionario WhoqolBref de la Organización Mundial de la Salud. Se empleó estadística no paramétrica a través de la prueba de Correlación de Spearman y U de Mann Whitney. Resultados: En cuanto a la relación entre el funcionamiento familiar y la calidad de vida, se encontró que la funcionalidad familiar se relacionó con la calidad de vida global (p= 0,011), psicológica (p= 0,008), social (p= 0,010) y ambiental (p= 0,001). Conclusiones: Es importante considerar que los factores que intervienen en el funcionamiento familiar y la calidad de vida del adulto mayor podrían afectar el avance de la enfermedad, generar complicaciones y afectar una adecuada aceptación y el mejoramiento de la salud.

ABSTRACT Objective: To identify the relationship between family functioning and quality of life in older adults with High Blood Pressure. Material and Method: Descriptive, correlational and cross-sectional study in a population of older adults with high blood pressure belonging to the community center Las Culturas of Health Jurisdiction III in Matamoros, Tamaulipas, Mexico, identified through convenience sampling with adults who attended for consultation between August to December 2019. The subjects were administered the Family APGAR Test (Cronbach's Alpha .83) and the WhoqolBref questionnaire of the World Health Organization. Non-parametric statistics were used applying Spearman's Correlation test and Mann-Whitney U test. Results: Regarding the relationship between family functioning and quality of life, it was found that family functionality was related to overall quality of life (p= .011), psychological (p= .008), social (p= .010) and environmental (p= .001). Conclusions: It is important to consider that the factors involved in the family functioning and quality of life of the older adults could affect the progression of the disease, cause complications and affect adequate acceptance and improvement of health.

RESUMO Objetivo: Identificar a relação entre o funcionamento familiar e a qualidade de vida em idosos com hipertensão arterial. Material e Método: Estudo descritivo, correlacional e transversal em uma população de idosos com hipertensão arterial pertencente ao centro comunitário Las Culturas da Jurisdição de Saúde III em Matamoros, Tamaulipas, México, identificados através de amostragem por conveniência com adultos que participaram de consulta entre agosto e dezembro de 2019. O sujeitos foram entregues o Teste APGAR familiar (Alfa de Cronbach .83) e ou questionário WhoqolBref da Organização Mundial da Saúde. Estatísticas não paramétricas foram utilizadas aplicando o teste de correlação de Spearman e o teste Mann-Whitney U. Resultados: Quanto à relação entre o funcionamento familiar e a qualidade de vida, verificou-se que a funcionalidade familiar está relacionada à qualidade da vida em geral (p= ,011), psicológica (p= ,008), social (p= ,010) e ambiental (p ,001). Conclusão: É importante considerar que os fatores envolvidos no funcionamento da família e na qualidade de vida dos idosos podem afetar a progressão da doença, causar complicações e afetar a aceitação adequada e a melhoria da saúde.

Estrategias para empoderar a las mujeres en relación con los derechos reproductivos y la planificación familiar: revisión sistemática desde las corrientes bioéticas / Strategies to empower women in relation to reproductive rights and family planning: a systematic review from bioethical currents / Estratégias para empoderar as mulheres em relação aos direitos reprodutivo e de planejamento familiar: revisão sistemática desde las correntes bioéticas

Resumen El presente artículo informa de una investigación cuyo objetivo fue definir las estrategias para empoderar a las mujeres mexicanas en sus decisiones de planificación familiar y de establecer compromisos y responsabilidades con sus parejas. Se realizó una revisión sistemática, incluyendo PubMed, Redalyc y Scopus, y se incluyeron diez artículos originales de dos continentes y diversas poblaciones. De los estudios realizados en México y Latinoamérica ninguno proporcionó una propuesta para implementar mejoras en la adopción de un método de planificación familiar entre las mujeres que viven violencia de pareja. Se concluye que la capacitación y formación bioética del personal de salud puede abonar a lograr que el proceso de información y decisión por parte de la mujer o de la pareja sean llevados a cabo con apego a la bioética, buscando el beneficio individual y protección del bienestar de la mujer y, por ende, de su familia.

Abstract This article reports on research aimed at defining strategies to empower Mexican women in their family planning decisions and to establish commitments and responsibilities with their partners. A systematic review was conducted, including PubMed, Redalyc and Scopus, and ten original articles from two continents and diverse populations were included. Of the studies conducted in Mexico and Latin America, none provided a proposal to implement improvements in the adoption of a family planning method among women who experience intimate partner violence. It is concluded that bioethical training and education of health personnel can contribute to ensure that the information and decision-making process by the woman or the couple is carried out in accordance with bioethics, seeking individual benefit and protection of the wellbeing of the woman and, therefore, of her family.

Resumo O presente artigo informa sobre uma pesquisa cujo objetivo foi definir as estratégias para empoderar as mulheres mexicanas em suas decisões de planejamento familiar e de estabelecer compromissos e responsabilidades com seus companheiros. Foi realizada uma revisão sistemática, incluindo PubMed, Redalyc e Scopus, e se incluíram dez artigos originais de dois continentes e diversas populações. Dos estudos realizados no México e na América Latina nenhum proporcionou uma proposta para implementar melhorias na adoção de um método de planejamento familiar entre as mulheres que sofrem violência conjugal. Conclui-se que a capacitação e formação bioética do pessoal de saúde pode lograr alcançar que o processo de informação e decisão por parte da mulher ou do casal sejam levados a cabo com apego à bioética, buscando o beneficio individual e a proteção do bem estar da mulher e, por conseguinte, de sua família.

Psychosocial impact on health-related and non-health related university students during the COVID-19 pandemic. Results of an electronic survey.

INTRODUCTION: The current SARS-CoV-2 pandemic has caused feelings of anxiety, confusion, and panic among the world population. Due to these psychological changes resulting from the stress produced by the disease, we sought to investigate the psychological impact of the pandemic on the university student community. MATERIAL AND METHODS: 1,283 students were surveyed, of which 1,149 students were selected. The majority of the subjects were female, and the overall average age was of 20 years. They were provided with an 82-question online questionnaire divided into four sections; looking for the prevalence of significant symptomatology of major depression and generalised anxiety using the PHQ-9 and GAD-7 scales; and factors that potentially affect the mental health of our university population. RESULTS: We found a high prevalence of significant depression (47.08%) and anxiety (27.06%) symptomatology, considering a score of 10 or more as cut-off point. There was no significant difference in depression and anxiety symptomatology between the health-care students and non-health-care students. CONCLUSIONS: Our results, together with what is observed in the literature, allow us to conclude that the college student population has a high risk of mental illness, and these should be taken into consideration for the search of effective strategies for detection and control of mental health illnesses. Undoubtedly, the COVID-19 pandemic is a red flag that shows the need to upgrade mental health programmes in universities and to validate virtual instruments.