RESUMO
BACKGROUND: Verrucae plantaris is a viral disease caused by human papilloma virus that is commonly seen in the office setting and is often challenging to treat owing to its high recurrence rate and recalcitrant profile. Candida albicans intralesional injections have been hypothesized to incite an immunogenic response toward the virus. METHODS: We report on the immunotherapeutic effect of intralesional injection of C albicans into plantar verrucae with a retrospective medical record analysis of 80 patients. Using a luer-lock syringe, 0.1 to 0.3 mL of C albicans antigen was injected into either the first known lesion or the largest lesion. RESULTS: The success rate of intralesional C albicans, defined as total clearance of the lesion, was 65%, which may be underestimated because patients lost to follow-up were included in the 35% failure rate. It was also found that female patients with a previous tissue-destructive treatment process were more than four times more likely to respond to C albicans therapy, whereas this effect was less pronounced in the male patient population. CONCLUSIONS: These results indicate that a series of intralesional injections of C albicans is an effective and efficient method of treatment for verrucae plantaris.
Assuntos
Antígenos de Fungos/administração & dosagem , Candida albicans/imunologia , Doenças do Pé/terapia , Imunoterapia/métodos , Verrugas/tratamento farmacológico , Adulto , Feminino , Humanos , Injeções Intralesionais , Masculino , Estudos Retrospectivos , Resultado do Tratamento , Verrugas/diagnósticoRESUMO
The standard incisional approaches for ankle and subtalar joint surgery include the medial, lateral, or anterior. However, in patients with a history of traumatic injuries or previous surgery, in which the soft tissues of the foot and ankle have been compromised, a direct midline posterior approach might be preferable. The approach offers unparalleled exposure, provides excellent frontal plane visualization, and reduces the risk of vascular compromise by preserving the surrounding angiosomes. We report on 2 separate cases in which a midline posterior approach to the ankle and subtalar joints was used successfully for fusion procedures of the tibiocalcaneal and subtalar joints.
