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1.
J Imaging Inform Med ; 37(2): 489-503, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38316666

RESUMO

Peer review plays a crucial role in accreditation and credentialing processes as it can identify outliers and foster a peer learning approach, facilitating error analysis and knowledge sharing. However, traditional peer review methods may fall short in effectively addressing the interpretive variability among reviewing and primary reading radiologists, hindering scalability and effectiveness. Reducing this variability is key to enhancing the reliability of results and instilling confidence in the review process. In this paper, we propose a novel statistical approach called "Bayesian Inter-Reviewer Agreement Rate" (BIRAR) that integrates radiologist variability. By doing so, BIRAR aims to enhance the accuracy and consistency of peer review assessments, providing physicians involved in quality improvement and peer learning programs with valuable and reliable insights. A computer simulation was designed to assign predefined interpretive error rates to hypothetical interpreting and peer-reviewing radiologists. The Monte Carlo simulation then sampled (100 samples per experiment) the data that would be generated by peer reviews. The performances of BIRAR and four other peer review methods for measuring interpretive error rates were then evaluated, including a method that uses a gold standard diagnosis. Application of the BIRAR method resulted in 93% and 79% higher relative accuracy and 43% and 66% lower relative variability, compared to "Single/Standard" and "Majority Panel" peer review methods, respectively. Accuracy was defined by the median difference of Monte Carlo simulations between measured and pre-defined "actual" interpretive error rates. Variability was defined by the 95% CI around the median difference of Monte Carlo simulations between measured and pre-defined "actual" interpretive error rates. BIRAR is a practical and scalable peer review method that produces more accurate and less variable assessments of interpretive quality by accounting for variability within the group's radiologists, implicitly applying a standard derived from the level of consensus within the group across various types of interpretive findings.

2.
Pain Med ; 24(Suppl 1): S81-S94, 2023 08 04.
Artigo em Inglês | MEDLINE | ID: mdl-36069660

RESUMO

Management of patients suffering from low back pain (LBP) is challenging and requires development of diagnostic techniques to identify specific patient subgroups and phenotypes in order to customize treatment and predict clinical outcome. The Back Pain Consortium (BACPAC) Research Program Spine Imaging Working Group has developed standard operating procedures (SOPs) for spinal imaging protocols to be used in all BACPAC studies. These SOPs include procedures to conduct spinal imaging assessments with guidelines for standardizing the collection, reading/grading (using structured reporting with semi-quantitative evaluation using ordinal rating scales), and storage of images. This article presents the approach to image acquisition and evaluation recommended by the BACPAC Spine Imaging Working Group. While the approach is specific to BACPAC studies, it is general enough to be applied at other centers performing magnetic resonance imaging (MRI) acquisitions in patients with LBP. The herein presented SOPs are meant to improve understanding of pain mechanisms and facilitate patient phenotyping by codifying MRI-based methods that provide standardized, non-invasive assessments of spinal pathologies. Finally, these recommended procedures may facilitate the integration of better harmonized MRI data of the lumbar spine across studies and sites within and outside of BACPAC studies.


Assuntos
Degeneração do Disco Intervertebral , Dor Lombar , Humanos , Vértebras Lombares/diagnóstico por imagem , Vértebras Lombares/patologia , Região Lombossacral , Dor Lombar/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos
3.
Arthroscopy ; 37(2): 541-551, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-33359757

RESUMO

PURPOSE: To evaluate the clinical and radiological outcome, sum of acetabular and femoral cartilage thickness, and rate of failure in the midterm after arthroscopic treatment of femoroacetabular impingement (FAI) syndrome with femoral osteoplasty, labral repair, and rim trimming without labral detachment. METHODS: This retrospective case series included patients with FAI syndrome who had undergone hip arthroscopy from January 2009 to December 2010 by a single surgeon, with a minimum follow-up of 55 months. Data from patients who had undergone arthroscopic hip procedures with labral repair, rim trimming, and femoral osteoplasty were analyzed pre- and postoperatively. Clinical outcome (nonarthritic hip score [NAHS], Short Form 36 [SF-36]), range of motion, progression of osteoarthritis (Tönnis grade), radiological parameters (α angle, lateral center-edge angle [LCEA], Tönnis angle), femoral and acetabular cartilage thickness (using magnetic resonance imaging [MRI]), and intraoperative findings were evaluated. RESULTS: Of 148 hip arthroscopies performed, 97 included rim trimming, labral refixation, and femoral osteoplasty. Ten cases were lost to follow-up, leaving 87 hips. Arthroscopic revision was performed on 4 hips and total hip replacement on 4 hips, and 1 hip underwent both arthroscopic revision and total hip replacement. Excluding these 9 cases of revision, for which follow-up was not possible (retrospective study), the remaining 78 hips were followed up for a minimum of 55 months (77 ± 11.4, mean ± SD; range 55 to 124). Mean NAHS (65 to 88, P < .001), SF-36 physical subscale (65 to 85, P < .001), and the numerical pain rating scale (NRS) (5 to 1, P < .001) improved significantly. Outcome scores of minimal clinical importance (NAHS) were achieved in 67.6% of the patients. Mean range of movement improved significantly in flexion (109 to 122, P < .001) and internal rotation (10 to 22.7, P < .001). NAHS was positively associated with flexion of the hip postoperatively (r = 0.307, P = .011). In 16 cases, microfracture was performed (15 acetabular and 1 femoral). Preoperative α angles (anteroposterior and modified Dunn) were significantly higher in this cohort (P < .001, 95% confidence interval 8.9 to 25.2, P = .001). Twenty hips (28 %) progressed to worse Tönnis grades. Initial Tönnis grades were grade 0, 38; grade 1, 48; grade 2, 8. Pre- or postoperative Tönnis grades did not show any correlation with pre- or postoperative NAHS and NRS. MRI measurements at the latest follow-up (69 patients) of the femoral and acetabular cartilage thickness did not reveal any significant reduction at the 12 o'clock position. CONCLUSION: Arthroscopic cam resection, rim trimming, and labral repair without detachment of the labrum provides good or excellent outcome in 77.1% of hips based on NAHS in the midterm. Higher range of motion in flexion is associated with higher NAHS postoperatively. Arthroscopic cam resection, rim trimming and labral repair without detachment of the labrum is a successful method for the treatment of FAI syndrome in the midterm. LEVEL OF EVIDENCE: IV, retrospective case series.


Assuntos
Artroscopia , Cartilagem/diagnóstico por imagem , Cartilagem/cirurgia , Acetábulo/diagnóstico por imagem , Acetábulo/fisiopatologia , Acetábulo/cirurgia , Cartilagem/fisiopatologia , Feminino , Impacto Femoroacetabular/cirurgia , Fêmur/cirurgia , Seguimentos , Humanos , Imageamento por Ressonância Magnética , Masculino , Medidas de Resultados Relatados pelo Paciente , Amplitude de Movimento Articular , Estudos Retrospectivos , Resultado do Tratamento
5.
Br J Radiol ; 93(1105): 20190738, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31642691

RESUMO

OBJECTIVE: To investigate the value of MRI in comparison to single photon emission computed tomography (SPECT)/CT in patients with painful hip arthroplasties. METHODS: A prospective, multi-institutional study was performed. Therefore, 35 consecutive patients (21 female, 14 male, mean age 61.8 ± 13.3 years) with 37-painful hip arthroplasties were included. A hip surgeon noted the most likely diagnosis based on clinical examination and hip radiographs. Then, MRI and SPECT/CT of the painful hips were acquired. MRI and SPECT/CT were assessed for loosening, infection, fracture, tendon pathology and other abnormalities. Final diagnosis and therapy was established by the hip surgeon after integration of MRI and SPECT/CT results. The value of MRI and SPECT/CT for diagnosis was assessed with a 3-point scale (1 = unimportant, 2 = helpful, 3 = essential). RESULTS: Loosening was observed in 13/37 arthroplasties (6 shaft only, 6 cup only, 1 combined). Sensitivity, specificity, positive predictive value and negative predictive value for loosening of MRI were 86%/88%/60%/100% and of SPECT/CT 93%/97%/90%/100%, respectively. MRI and SPECT/CT diagnosed infection correctly in two of three patients and fractures in two patients, which were missed by X-ray. MRI detected soft tissue abnormalities in 21 patients (6 bursitis, 14 tendon lesions, 1 pseudotumor), of which only 1 tendon abnormality was accurately detected with SPECT/CT. All 5 arthroplasties with polyethylene wear were correctly diagnosed clinically and with both imaging modalities. MRI and SPECT/CT were judged as not helpful in 0/0%, as helpful in 16%/49% and essential in 84%/51%. CONCLUSION: In patients with painful hip arthroplasty SPECT/CT is slightly superior to MR in the assessment of loosening. MRI is far superior in the detection of soft tissue, especially tendon pathologies. ADVANCES IN KNOWLEDGE: To our knowledge this is the first prospective, multiinstitutional study which compares MRI with SPECT/CT in painful hip arthroplasties. We found that MRI is far superior in the detection of soft tissue pathologies, whereas SPECT/CT remains slightly superior regarding loosening.


Assuntos
Artroplastia de Quadril , Imageamento por Ressonância Magnética/métodos , Dor Pós-Operatória/diagnóstico por imagem , Infecções Relacionadas à Prótese/diagnóstico por imagem , Tomografia Computadorizada de Emissão de Fóton Único/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Medição da Dor , Valor Preditivo dos Testes , Falha de Prótese , Sensibilidade e Especificidade
6.
Eur Spine J ; 28(10): 2266-2274, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31446492

RESUMO

PURPOSE: The positive association between low back pain and MRI evidence of vertebral endplate bone marrow lesions, often called Modic changes (MC), offers the exciting prospect of diagnosing a specific phenotype of chronic low back pain (LBP). However, imprecision in the reporting of MC has introduced substantial challenges, as variations in both imaging equipment and scanning parameters can impact conspicuity of MC. This review discusses key methodological factors that impact MC classification and recommends guidelines for more consistent MC reporting that will allow for better integration of research into this LBP phenotype. METHODS: Non-systematic literature review. RESULTS: The high diagnostic specificity of MC classification for a painful level contributes to the significant association observed between MC and LBP, whereas low and variable sensitivity underlies the between- and within-study variability in observed associations. Poor sensitivity may be owing to the presence of other pain generators, to the limited MRI resolution, and to the imperfect reliability of MC classification, which lowers diagnostic sensitivity and thus influences the association between MC and LBP. Importantly, magnetic field strength and pulse sequence parameters also impact detection of MC. Advances in pulse sequences may improve reliability and prove valuable for quantifying lesion severity. CONCLUSIONS: Comparison of MC data between studies can be problematic. Various methodological factors impact detection and classification of MC, and the lack of reporting guidelines hinders interpretation and comparison of findings. Thus, it is critical to adopt imaging and reporting standards that codify acceptable methodological criteria. These slides can be retrieved under Electronic Supplementary Material.


Assuntos
Medula Óssea/diagnóstico por imagem , Vértebras Lombares/diagnóstico por imagem , Imageamento por Ressonância Magnética , Humanos , Dor Lombar/etiologia
7.
J Anesth ; 33(2): 279-286, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-30863957

RESUMO

PURPOSE: Shoulder dislocation is often associated with intense pain, and requires urgent pain therapy and reduction. Interscalene block, general anesthesia, or intravenous analgesia alone are applied procedures that facilitate shoulder reduction by the surgeon and ease patients' pain. This study was conducted to compare procedure times, patient satisfaction, side-effects, and clinical outcome of these clinical procedures. METHODS: Retrospective chart analysis was performed for all patients treated at the Emergency Department of a primary care hospital. In addition, standardized telephone interviews were conducted. Subjective clinical outcome and patient satisfaction (SF-36, Quick-DASH, ZUF-8) were measured with the standardized questionnaires. RESULTS: The shortest overall procedure time [67.5 min (48.8-93.5 min), P = 0.003] was found in patients with interscalene block. The advantage of general anesthesia was the shortest anesthesia induction time [10 min (7.8-10 min), P < 0.0001]; reduction time [6 min (4.3-6 min), P = 0.039]; and time to discharge [90 min (67.5-123.8 min), P = 0.0001] were significantly prolonged in comparison to interscalene block [5 min (1-5 min) and 45 min (2-67.5 min)]. The longest reduction time [11 min (10-13.5 min), P = 0.0008] was seen in patients in the intravenous analgesia group. Overall, patient satisfaction was greater in patients with regional as compared to general anesthesia [measured by ZUF-8: 12 (9-15) vs. 17 (12-24), P = 0.03]. Subjective clinical outcome (SF-36, DASH) was comparable among the three groups. There was one immediately identified esophageal intubation in the general anesthesia group. CONCLUSIONS: Out-patient shoulder reduction can be accomplished no matter whether general anesthesia, regional anesthesia, or intravenous analgesia alone was administered. Clinical outcome as measured by SF-36 and DASH was comparable among the three groups, but the shortest overall procedure time and greater patient satisfaction were found in patients with interscalene block.


Assuntos
Analgesia/métodos , Anestesia Geral/métodos , Anestésicos Locais/administração & dosagem , Ombro/cirurgia , Adulto , Idoso , Bloqueio do Plexo Braquial/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pacientes Ambulatoriais , Manejo da Dor , Medição da Dor , Dor Pós-Operatória/tratamento farmacológico , Satisfação do Paciente , Estudos Retrospectivos
9.
PM R ; 10(3): 245-253, 2018 03.
Artigo em Inglês | MEDLINE | ID: mdl-28797833

RESUMO

BACKGROUND: Although lumbar zygapophyseal joint synovial cysts are fairly well recognized, they are an uncommon cause of lumbosacral radicular pain. Nonoperative treatments include percutaneous aspiration of the cysts under computed tomography or fluoroscopic guidance with a subsequent corticosteroid injection. However, there are mixed results in terms of long-term outcomes and cyst reoccurrence. This study prospectively evaluates percutaneous ruptures of zygapophyseal joint (Z-joint) synovial cysts for the treatment of lumbosacral radicular pain. OBJECTIVES: Primary: To determine whether percutaneous rupture of symptomatic Z-joint synovial cysts leads to sustained improvements in radicular pain and function. Secondary: To assess the rates of cyst recurrence and progression to surgical intervention following percutaneous rupture of symptomatic Z-joint synovial cysts. DESIGN: Prospective cohort study. SETTING: Outpatient academic spine practice. PARTICIPANTS: Adults with primary radicular pain due to a facet synovial cyst. METHODS: Participants underwent fluoroscopically guided percutaneous Z-joint synovial cyst ruptures under standard-of-care practice. Data on pain, physical function, satisfaction, and progression to surgery were collected at 2 weeks, 6 weeks, 3 months, 6 months, and 1 year after rupture. An intention-to-treat analysis was used for assessment of patient-reported outcome measures. MAIN OUTCOME MEASURES: The Numerical Rating Scale, Oswestry Disability Index, and modified North American Spine Society questionnaires were used to measure pain, function, and satisfaction with the procedure, respectively. RESULTS: Thirty-five participants were included in the study, and data were analyzed by an independent researcher. Statistically significant changes in Oswestry Disability Index were reported at 2 weeks, 3 months, and 1 year postintervention (P = .034, .040, and .039, respectively). A statistically and clinically significant relief of current pain was reported at 2 weeks (P = .025) and 6 weeks (P = .014) with respect to baseline. Patients showed significant improvements for best pain at 6 weeks with respect to baseline (P = .031). Patients' worst pain showed the greatest amount of improvement with clinically meaningful changes at all time points compared with baseline. Patient-reported satisfaction was found nearly 70% of the time at all time points. Forty percent (14/35) of participants required repeat cyst rupture, and 31% (11/35) required surgical interventions. CONCLUSIONS: There were statistically and clinically significant improvements in pain and function after percutaneous rupture of Z-joint synovial cysts. In addition, the outcomes support previous retrospective studies indicating that approximately 40% of patients will need surgery. This study provides further research to determine the utility of this procedure and to precisely define a subset of ideal candidates. LEVEL OF EVIDENCE: Level II.


Assuntos
Tratamento Conservador/métodos , Dor Lombar/terapia , Vértebras Lombares , Procedimentos Ortopédicos/métodos , Cisto Sinovial/terapia , Articulação Zigapofisária , Idoso , Idoso de 80 Anos ou mais , Feminino , Fluoroscopia , Seguimentos , Humanos , Dor Lombar/diagnóstico , Dor Lombar/etiologia , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Cisto Sinovial/complicações , Cisto Sinovial/diagnóstico , Tomografia Computadorizada por Raios X , Resultado do Tratamento
10.
Arthrosc Tech ; 6(2): e397-e400, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28580258

RESUMO

Most surgeons create a T-shaped or interportal capsulotomy to ensure good visibility when performing hip arthroscopy. This entails transecting the iliofemoral ligament, which may or may not be repaired at the end of the procedure. Cases of iatrogenic hip instability and pain after hip arthroscopy suggest that the iliofemoral ligament plays a crucial role in the stability of the hip joint, and thus preservation should be a goal in hip arthroscopy. We describe a minimally invasive iliofemoral ligament-sparing capsulotomy, guided by the reflected head of the rectus tendon, that can be easily repaired after arthroscopic rim trimming, labral refixation, and offset correction.

12.
Eur Radiol ; 27(6): 2507-2520, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-27709276

RESUMO

OBJECTIVES: The association of disc degeneration (DD) and vertebral endplate degeneration (EPD) is still not well understood. This study aimed to find segmental predictive risk factors for DD and EPD and to illuminate associations of the disc, endplate and bone marrow changes in the process of degeneration. METHODS: After institutional review board approval, 450 lumbar levels, followed up with MRI for at least 4 years, were retrospectively graded for DD according to Pfirrmann (PFG), for EPD according to the endplate score (EPS) and according to the presence, extension and type of Modic changes (MC). Clustered logistic regression and multivariate analysis was applied in nested, matched case-control subgroups to evaluate potential local risk factors for progression. RESULTS: An EPS score of ≥4 was identified as an independent risk factor for progression of DD (OR = 2.32, 95%CI:1.07-5.01,p = 0.03) and MC (OR = 5.49,95%CI:2.30-13.10,p < 0.001). Progression of DD was significantly accompanied by progression or evolution of MC (OR = 12.25,95%CI:1.49-100.6,p = 0.02) and with progression of EPS (OR = 1.71, 95%CI:1.00-1.05, p = 0.01). Once advanced DD has occurred, it becomes a risk factor for progression in EPS (OR = 2.24,95%CI:1.23-4.12,p < 0.01). CONCLUSIONS: The degenerative processes in the disc, endplate and bone marrow are highly associated. An EPS ≥ 4 is an independent risk factor for DD and MC progression in a population with low back pain. KEY POINTS: • The degenerative processes in the disc, endplate and bone marrow are associated. • An endplate score ≥4 is a risk factor for DD and MC progression. • Modic changes are last to occur in the development of segmental intervertebral degeneration. • A new segmental grading system is suggested.


Assuntos
Doenças da Medula Óssea/patologia , Progressão da Doença , Degeneração do Disco Intervertebral/patologia , Vértebras Lombares/patologia , Estudos de Casos e Controles , Métodos Epidemiológicos , Feminino , Humanos , Disco Intervertebral/patologia , Dor Lombar/etiologia , Dor Lombar/patologia , Imageamento por Ressonância Magnética/métodos , Masculino , Pessoa de Meia-Idade
13.
Spine J ; 17(4): 554-561, 2017 04.
Artigo em Inglês | MEDLINE | ID: mdl-27867079

RESUMO

BACKGROUND CONTEXT: In today's health-care climate, magnetic resonance imaging (MRI) is often perceived as a commodity-a service where there are no meaningful differences in quality and thus an area in which patients can be advised to select a provider based on price and convenience alone. If this prevailing view is correct, then a patient should expect to receive the same radiological diagnosis regardless of which imaging center he or she visits, or which radiologist reviews the examination. Based on their extensive clinical experience, the authors believe that this assumption is not correct and that it can negatively impact patient care, outcomes, and costs. PURPOSE: This study is designed to test the authors' hypothesis that radiologists' reports from multiple imaging centers performing a lumbar MRI examination on the same patient over a short period of time will have (1) marked variability in interpretive findings and (2) a broad range of interpretive errors. STUDY DESIGN: This is a prospective observational study comparing the interpretive findings reported for one patient scanned at 10 different MRI centers over a period of 3 weeks to each other and to reference MRI examinations performed immediately preceding and following the 10 MRI examinations. PATIENT SAMPLE: The sample is a 63-year-old woman with a history of low back pain and right L5 radicular symptoms. OUTCOME MEASURES: Variability was quantified using percent agreement rates and Fleiss kappa statistic. Interpretive errors were quantified using true-positive counts, false-positive counts, false-negative counts, true-positive rate (sensitivity), and false-negative rate (miss rate). METHODS: Interpretive findings from 10 study MRI examinations were tabulated and compared for variability and errors. Two of the authors, both subspecialist spine radiologists from different institutions, independently reviewed the reference examinations and then came to a final diagnosis by consensus. Errors of interpretation in the study examinations were considered present if a finding present or not present in the study examination's report was not present in the reference examinations. RESULTS: Across all 10 study examinations, there were 49 distinct findings reported related to the presence of a distinct pathology at a specific motion segment. Zero interpretive findings were reported in all 10 study examinations and only one finding was reported in nine out of 10 study examinations. Of the interpretive findings, 32.7% appeared only once across all 10 of the study examinations' reports. A global Fleiss kappa statistic, computed across all reported findings, was 0.20±0.06, indicating poor overall agreement on interpretive findings. The average interpretive error count in the study examinations was 12.5±3.2 (both false-positives and false-negatives). The average false-negative count per examination was 10.9±2.9 out of 25 and the average false-positive count was 1.6±0.9, which correspond to an average true-positive rate (sensitivity) of 56.4%±11.7 and miss rate of 43.6%±11.7. CONCLUSIONS: This study found marked variability in the reported interpretive findings and a high prevalence of interpretive errors in radiologists' reports of an MRI examination of the lumbar spine performed on the same patient at 10 different MRI centers over a short time period. As a result, the authors conclude that where a patient obtains his or her MRI examination and which radiologist interprets the examination may have a direct impact on radiological diagnosis, subsequent choice of treatment, and clinical outcome.


Assuntos
Erros de Diagnóstico , Dor Lombar/diagnóstico por imagem , Vértebras Lombares/diagnóstico por imagem , Imageamento por Ressonância Magnética/normas , Idoso , Feminino , Humanos , Dor Lombar/diagnóstico
14.
J Bone Joint Surg Am ; 98(14): 1206-14, 2016 Jul 20.
Artigo em Inglês | MEDLINE | ID: mdl-27440569

RESUMO

BACKGROUND: Developmental cervical stenosis of the spinal canal predisposes patients to neural compression and loss of function. The Torg-Pavlov ratio has been shown to provide high sensitivity but low specificity for identifying developmental cervical stenosis. A more sensitive and specific radiographic index has not been reported to our knowledge. The objective of this study was to develop and provide an objective, sensitive, and specific radiographic index to assess for developmental cervical stenosis. METHODS: The C3 through C6 levels of the cervical spine were analyzed on lateral radiographs of 150 adult patients to determine the spinolaminar line-to-lateral mass distance (SL), lateral mass-to-posterior vertebral body distance (LM), spinolaminar line-to-vertebral body (canal) diameter (CD), and vertebral body diameter (VB). Ratios of these measurements were calculated to eliminate magnification effects. The corresponding true spinal canal diameter was measured using computed tomography (CT) midsagittal sections. Receiver operating characteristic (ROC) curve analysis was performed to identify a radiographic measurement ratio with optimal sensitivity and specificity, using a true canal diameter of <12 mm to define developmental cervical stenosis. RESULTS: Several of the measured ratios demonstrated a strong correlation with the true canal diameter at all cervical levels. However, ROC curve analysis showed that only an LM/CD ratio of ≥0.735 indicated a canal diameter of <12 mm (developmental cervical stenosis). The sensitivity of this ratio at C5 was 83% and its specificity at C5 was 74%. An LM/CD ratio of ≥0.735 measured only at the C5 level also indicated developmental cervical stenosis at any cervical level from C3 through C6 with 76% sensitivity and 80% sensitivity. Other ratios, including the Torg-Pavlov ratio, did not demonstrate an adequate statistical profile to indicate developmental cervical stenosis. The accuracy of the LM/CD ratio was not adversely affected by the patient's sex. CONCLUSIONS: This analysis provided a novel index for identifying developmental cervical stenosis: the C5 lateral mass/canal diameter (LM/CD) ratio. We believe that this ratio is the best radiographic measurement available to screen for developmental cervical stenosis in the adult spine patient population. It provides an objective radiographic screening tool for physicians to detect developmental cervical stenosis and decide whether additional imaging or surgical referral is appropriate. LEVEL OF EVIDENCE: Diagnostic Level II. See Instructions for Authors for a complete description of levels of evidence.


Assuntos
Vértebras Cervicais/diagnóstico por imagem , Estenose Espinal/diagnóstico por imagem , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Sensibilidade e Especificidade , Tomografia Computadorizada por Raios X
15.
Spine J ; 16(3): 273-80, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26133255

RESUMO

BACKGROUND CONTEXT: Provocative discography, an invasive diagnostic procedure involving disc puncture with pressurization, is a test for presumptive discogenic pain in the lumbar spine. The clinical validity of this test is unproven. Data from multiple animal studies confirm that disc puncture causes early disc degeneration. A recent study identified radiographic disc degeneration on magnetic resonance imaging (MRI) performed 10 years later in human subjects exposed to provocative discography. The clinical effect of this disc degeneration after provocative discography is unknown. PURPOSE: The aim of this study was to investigate the clinical effects of lumbar provocative discography on patients subjected to this evaluation method. STUDY DESIGN/SETTING: A prospective, 10-year matched cohort study. PATIENT SAMPLE: Subjects (n=75) without current low back pain (LBP) problems were recruited to participate in a study of provocative discography at the L3-S1 discs. A closely matched control cohort was simultaneously recruited to undergo a similar evaluation except for discography injections. OUTCOME MEASURES: The primary outcome variables were diagnostic imaging events and lumbar disc surgery events. The secondary outcome variables were serious LBP events, disability events, and medical visits. METHODS: The discography subjects and control subjects were followed by serial protocol evaluations at 1, 2, 5, and 10 years after enrollment. The lumbar disc surgery events and diagnostic imaging (computed tomography (CT) or MRI) events were recorded. In addition, the interval and cumulative lumbar spine events were recorded. RESULTS: Of the 150 subjects enrolled, 71 discography subjects and 72 control subjects completed the baseline evaluation. At 10-year follow-up, 57 discography and 53 control subjects completed all interval surveillance evaluations. There were 16 lumbar surgeries in the discography group, compared with four in the control group. Medical visits, CT/MRI examinations, work loss, and prolonged back pain episodes were all more frequent in the discography group compared with control subjects. CONCLUSION: The disc puncture and pressurized injection performed during provocative discography can increase the risk of clinical disc problems in exposed patients.


Assuntos
Degeneração do Disco Intervertebral/epidemiologia , Disco Intervertebral , Dor Lombar/epidemiologia , Complicações Pós-Operatórias/epidemiologia , Punções , Adulto , Estudos de Coortes , Feminino , Humanos , Injeções , Degeneração do Disco Intervertebral/diagnóstico por imagem , Degeneração do Disco Intervertebral/cirurgia , Estudos Longitudinais , Dor Lombar/diagnóstico por imagem , Dor Lombar/cirurgia , Vértebras Lombares/diagnóstico por imagem , Vértebras Lombares/cirurgia , Região Lombossacral , Imageamento por Ressonância Magnética , Masculino , Estudos Prospectivos , Tomografia Computadorizada por Raios X
16.
Spine J ; 15(10): 2122-5, 2015 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-26190156

RESUMO

The high incidence of failed back patients in the United States calls for a closer look at the source of the problem. In this paper I examine how variability in quality at the diagnostic stage can contribute to the problem. Although MRIs are widely perceived to be a commodity, I identify three key factors that create variability in the quality of an MRI: imaging equipment, imaging protocols, and subspecialization of the reading radiologist. To evaluate the impact of these quality variables, I am collaborating with Spreemo to run a clinical trial at Hospital for Special Surgery to determine the relationship between MRI quality measures and treatment recommendations, and ultimately patient outcomes.


Assuntos
Imageamento por Ressonância Magnética/métodos , Traumatismos da Coluna Vertebral/diagnóstico , Humanos
17.
Wien Klin Wochenschr ; 127(1-2): 71-4, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25398290

RESUMO

Spinal subdural hematoma (SSDH) following spine surgery is an extremely rare condition, with only three cases being reported in the literature. Unintended durotomy has been associated with SSDH due to alterations of pressures in the dural compartments. The objective of the present report was to report two rare cases of acute SSDH developed after lumbar decompressive surgery. In one of the patients, the diagnosis of SSDH was followed by urgent hematoma evacuation via durotomy due to the patient's worsening neurological symptoms. In the second patient, the SSDH was treated conservatively due to the absence of severe or progressive motor or sensory deficits. In conclusion, emergency evacuation via durotomy is the treatment of choice for patients with SSDH and neurologic impairment. Conservative management may be indicated in selected cases with absent motor and sensory deficits.


Assuntos
Descompressão Cirúrgica/efeitos adversos , Hematoma Subdural Espinal/etiologia , Hematoma Subdural Espinal/cirurgia , Vértebras Lombares/cirurgia , Estenose Espinal/complicações , Estenose Espinal/cirurgia , Idoso , Hematoma Subdural Espinal/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
18.
Eur Spine J ; 24(3): 600-8, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25223429

RESUMO

PURPOSE: Anatomical landmarks and their relation to the lumbar vertebrae are well described in subjects with normal spine anatomy, but not for subjects with lumbosacral transitional vertebra (LSTV), in whom correct numbering of the vertebrae is challenging and can lead to wrong-level treatment. The aim of this study was to quantify the value of different anatomical landmarks for correct identification of the lumbar vertebra level in subjects with LSTV. METHODS: After IRB approval, 71 subjects (57 ± 17 years) with and 62 without LSTV (57 ± 17 years), all with imaging studies that allowed correct numbering of the lumbar vertebrae by counting down from C2 (n = 118) or T1 (n = 15) were included. Commonly used anatomical landmarks (ribs, aortic bifurcation (AB), right renal artery (RRA) and iliac crest height) were documented to determine the ability to correctly number the lumbar vertebrae. Further, a tangent to the top of the iliac crests was drawn on coronal MRI images by two blinded, independent readers and named the 'iliac crest tangent sign'. The sensitivity, specificity and the interreader agreement were calculated. RESULTS: While the level of the AB and the RRA were found to be unreliable in correct numbering of the lumbar vertebrae in LSTV subjects, the iliac crest tangent sign had a sensitivity and specificity of 81 % and 64-88 %, respectively, with an interreader agreement of k = 0.75. CONCLUSION: While anatomical landmarks are not always reliable, the 'iliac crest tangent sign' can be used without advanced knowledge in MRI to most accurately number the vertebrae in subjects with LSTV, if only a lumbar spine MRI is available.


Assuntos
Pontos de Referência Anatômicos , Vértebras Lombares/anormalidades , Imageamento por Ressonância Magnética , Sacro/anormalidades , Adulto , Idoso , Feminino , Humanos , Vértebras Lombares/anatomia & histologia , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Estudos Retrospectivos , Sacro/anatomia & histologia , Sensibilidade e Especificidade
19.
Spine J ; 15(6): 1210-6, 2015 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-24216396

RESUMO

BACKGROUND CONTEXT: The relation between specific types of lumbosacral transitional vertebra and the degree of degeneration at and adjacent to the transitional level is unclear. It is also unknown whether the adjacent cephalad segment to a transitional vertebra is prone to greater degeneration than a normal L5-S1 level. PURPOSE: The purpose of this study was to evaluate the relation between specific lumbosacral transitional vertebra subtypes according to the Castellvi classification, and to determine the severity of degeneration at the transitional level and the adjacent cephalad segment. STUDY DESIGN: This study was a retrospective review. PATIENT SAMPLES: Ninety-two subjects with lumbosacral transitional vertebra grade 2 or higher and 94 control subjects without were retrieved from a picture archiving and communication system (PACS) search. OUTCOME MEASURES: Disc degeneration parameters at the transitional and at the adjacent cephalad level were measured. METHODS: After institutional review board approval, 92 subjects (42 men; mean age, 57±16 years) with lumbosacral transitional vertebra grade 2 or higher and 94 control subjects (41 men; mean age, 51±16 years) without were retrieved from a PACS search. Degeneration of the last two segments of the lumbar spine was quantified using the Pfirrmann and Modic classifications, along with documentation of annular tears, disc herniations, and disc height, and were compared between the two groups. Furthermore, L5-S1 levels in the control subjects were compared with the adjacent cephalad segments of the transitional vertebrae for the same parameters. RESULTS: Although the control subjects, at L5-S1, had moderate to severe degeneration by Pfirrmann grades (31%) and Modic changes ([MC] 20%), in comparison, the discs at the transitional level of the lumbosacral transitional vertebra group demonstrated significant less degeneration (3% and 1%, respectively; each p<.05). The adjacent cephalad segments of the lumbosacral transitional vertebra group showed significantly greater degeneration (Pfirrmann grade 5, 39%; MC, 30%) compared with the L4-L5 level in control subjects (16% and 11%, respectively; each p<.05). The severity of disc degeneration using all parameters correlated with the type of lumbosacral transitional vertebra. The degree of degeneration of L5-S1 in control subjects was similar to the adjacent cephalad segment in lumbosacral transitional vertebrae. CONCLUSION: Increasing the mechanical connection of a lumbosacral transitional vertebra protects the disc at the transitional level and predisposes the adjacent cephalad segment to greater degeneration. The adjacent cephalad segment had a comparable degree of degeneration as the L5-S1 level in control subjects.


Assuntos
Degeneração do Disco Intervertebral/patologia , Deslocamento do Disco Intervertebral/patologia , Vértebras Lombares/patologia , Sacro/patologia , Adulto , Idoso , Feminino , Humanos , Região Lombossacral/patologia , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
20.
Eur Spine J ; 23(9): 1863-8, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24898310

RESUMO

PURPOSE: Evolution and progression of disc and endplate bone marrow degeneration of the lumbar spine are thought to be multifactorial, yet, their influence and interactions are not understood. The aim of this study was to find association of potential predictors of evolution of degeneration of the lumbar spine. METHODS: Patients (n = 90) who underwent two lumbar magnetic resonance imaging (MRI) exams with an interval of at least 4 years and without any spinal surgery were included into the longitudinal cohort study with nested case-control analysis. Disc degeneration (DD) was scored according to the Pfirrmann classification and endplate bone marrow changes (EC) according to Modic in 450 levels on both MRIs. Potential variables for degeneration such as age, gender, BMI, scoliosis and sagittal parameters were compared between patients with and without evolution or progression of degenerative changes in their lumbar spine. A multivariate analysis aimed to identify the most important variables for progression of disc and endplate degeneration, respectively. RESULTS: While neither age, gender, BMI, sacral slope or the presence of scoliosis could be identified as progression factor for DD, a higher lordosis was observed in subjects with no progression (49° ± 11° vs 43° ± 12°; p = 0.017). Progression or evolution of EC was only associated with a slightly higher degree of scoliosis (10° ± 10° vs 6° ± 9°; p = 0.04) and not to any of the other variables. CONCLUSION: While a coronal deformity of the lumbar spine seems associated with evolution or progression of EC, a higher lumbar lordosis is protective for radiographic progression of DD. This implies that scoliotic deformity and lesser lumbar lordosis are associated with higher overall degeneration of the lumbar spine.


Assuntos
Degeneração do Disco Intervertebral/patologia , Lordose/patologia , Vértebras Lombares/patologia , Imageamento por Ressonância Magnética , Escoliose/patologia , Adulto , Idoso , Estudos de Casos e Controles , Progressão da Doença , Feminino , Seguimentos , Humanos , Modelos Logísticos , Estudos Longitudinais , Região Lombossacral/patologia , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Valor Preditivo dos Testes , Estudos Retrospectivos
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