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1.
Dan Med J ; 71(4)2024 Mar 08.
Artigo em Inglês | MEDLINE | ID: mdl-38533879

RESUMO

INTRODUCTION: Complications and recurrence within benign salivary gland surgery are not systematically registered in Denmark. Patient-reported outcome measures are increasingly included in clinical and health policy decision-making, and therefore it is crucial that this type of data is valid. A patient-reported questionnaire regarding outcome after benign parotid gland surgery has been developed and implemented in a national German database. We aimed to translate the Parotidectomy Outcome Inventory 8 (POI-8) into Danish and validate it. METHODS: The questionnaire was translated. The study population was recruited from a single centre from 6 December 2019 to 1 June 2022. Patients > 18 years of age who had undergone their first parotid salivary gland surgery for a benign tumour were included. The questionnaire underwent pilot-testing and test-retesting; it was sent to respondents twice at a 14-day interval. For the categorical variables, the reliability of the items was tested using the weighted kappa-coefficient. RESULTS: A weighted kappa coefficient of 0.74 and Cronbach's alpha of 0.78 were found. No significant difference was found between testing at day 0 and 14. CONCLUSIONS: We have translated and validated the Danish version of the POI-8, finding acceptable levels of the weighted kappa coefficient and Cronbach's alpha. We suggest the systematic use of PROMs in Danish healthcare and specifically in parotidectomy for benign neoplasms. FUNDING: No funding. TRIAL REGISTRATION: Not relevant.


Assuntos
Atenção à Saúde , Glândulas Salivares , Humanos , Reprodutibilidade dos Testes , Inquéritos e Questionários , Dinamarca
2.
Ugeskr Laeger ; 185(8)2023 02 20.
Artigo em Dinamarquês | MEDLINE | ID: mdl-36892321
3.
Pract Neurol ; 21(5): 427-430, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34050003

RESUMO

Cerebral radiation necrosis is the most serious late reaction to high doses of ionising radiation to the brain, and its treatment is generally unsatisfactory. We present a patient who developed cerebral radiation necrosis after protracted fluoroscopy during repeated embolisations of an extracranial arteriovenous malformation. Treatment with bevacizumab (a humanised murine monoclonal antibody against vascular endothelial growth factor) was followed by neurological and radiological improvements.


Assuntos
Lesões por Radiação , Fator A de Crescimento do Endotélio Vascular , Animais , Bevacizumab/efeitos adversos , Humanos , Doença Iatrogênica , Camundongos , Necrose/etiologia , Lesões por Radiação/complicações
4.
World J Plast Surg ; 8(3): 331-337, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31620335

RESUMO

BACKGROUND: Closure of skin defects after scalp surgery may be accomplished by grafting; either split- or full-thickness. Both methods are used in Denmark, and the optimal approach on scalp defects without exposed bone is not known. This study aimed to investigate if the two methods were equal regarding graft take as primary outcome and as secondary outcomes complications and number of outpatient visits/ number of days from surgery until the last outpatient visit for the recipient site (as a proxy for time to healing), hypothesizing that they were. METHODS: The present retrospective single-center case series reported our experience using the two types of skin grafts after scalp surgery in the inclusion period from 1.1.2014 to 30.09.2015. Data were analyzed according to graft type with a full-thickness skin graft (FTSG-group) or a split-thickness skin graft (STSG-group). RESULTS: In the inclusion period, 106 patients had surgery (28 with a FTSG and 78 with a STSG). Irrespectively of which skin graft that was used, we found no statistically significant difference regarding percentage of adherence, complications or number of outpatient visits and time from operation until last outpatient visit regarding the recipient site (p>0.05). CONCLUSION: Our findings supported that use of either FTSG or STSG in scalp lesions were equal choices.

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