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5.
Arch Dermatol Res ; 315(4): 933-942, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-36416976

RESUMO

There is controversy regarding the optimal surgical modality and ideal recommended margins for treating melanoma in situ (MIS) and invasive melanoma (IM). Although wide local excision is recommended, staged excision offers excellent margin control and low recurrence rates. In this manuscript, we reviewed a 10-year experience of staged excisions for the treatment of MIS and IM. A retrospective review was performed of 130 MIS and 32 IM cases treated with staged excision from April 2012 to April 2022. Staged excision was performed on the head and neck in 102 (79%) MIS and 23 (72%) IM cases. Approximately 10% of cases required surgical margins above the current recommendations (11 (9%) MIS and 6 (19%) IM). Twenty-three (19%) MIS and 7 (22%) IM cases required more than one excision to obtain clearance. Recurrence rates among MIS and IM were 0.0% and 0.6%, respectively. Upstaging occurred in 5 (4%) MIS and 7 (22%) IM cases. Complex repairs were performed on 82 (63%) MIS and 17 (53%) IM cases. Our findings revealed that staged excision provides effective margin control and low recurrence rates. Approximately 10% of patients required margins greater than the current recommendations, leading to larger defects and more complex repairs.


Assuntos
Melanoma , Neoplasias Cutâneas , Humanos , Melanoma/patologia , Neoplasias Cutâneas/patologia , Estudos Retrospectivos , Recidiva Local de Neoplasia/epidemiologia , Recidiva Local de Neoplasia/cirurgia , Recidiva Local de Neoplasia/patologia , Margens de Excisão , Melanoma Maligno Cutâneo
6.
Facial Plast Surg ; 39(2): 180-184, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36075379

RESUMO

Nasal reconstruction has important functional and cosmetic considerations, as proper repair of nasal defects is necessary to maintain function of the nasal airway and to recreate the normal appearance of this central facial structure. Cheek advancement flaps provide matched, mobile, and highly vascularized tissue for the reconstruction of nasal defects, allowing for the concealment of incisions within natural creases in a one-stage approach. However, cheek advancement flaps are often underutilized for nasal reconstruction because of their difficulty in restoring nasal contour. We describe reconstruction of 19 nasal dorsal and sidewall defects 0.8 to 3 cm in size. We incorporated a periosteal anchoring suture to maintain/restore nasal contour and additionally removed a half standing cone inferior to the defect to prevent encroachment of the nasal ala or alar crease. All patients were evaluated at least 3 months postoperatively. In all patients, we were able to restore concavity of the nasofacial sulcus, preserve the biconvex nasal tips, prevent alar flaring and retraction, and conserve the alar groove. All patients had excellent functional and cosmetic outcomes. We believe this modified cheek advancement flap provides functionally and aesthetically superior results and can be considered as a first-line approach for repair of nasal dorsal and sidewall defects in subselected patients.


Assuntos
Neoplasias Nasais , Procedimentos de Cirurgia Plástica , Humanos , Bochecha/cirurgia , Neoplasias Nasais/cirurgia , Retalhos Cirúrgicos , Nariz/cirurgia
7.
Obstet Gynecol ; 140(4): 679-695, 2022 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-36075066

RESUMO

Pregnancy dermatoses are inflammatory skin disorders that occur during pregnancy or immediately postpartum. This heterogenous group of disorders includes pemphigoid gestationis, polymorphic eruption of pregnancy, intrahepatic cholestasis of pregnancy, atopic eruption of pregnancy, and pustular psoriasis of pregnancy. In this article, we provide a comprehensive literature review of each condition focusing on nomenclature, epidemiology, pathogenesis, clinical presentation, diagnosis, differential diagnosis, maternal risk, fetal risk, and treatment. We aim to increase awareness and help clinicians recognize, diagnose, and manage these unique conditions.


Assuntos
Colestase Intra-Hepática , Penfigoide Gestacional , Complicações na Gravidez , Dermatopatias , Feminino , Gravidez , Humanos , Complicações na Gravidez/terapia , Complicações na Gravidez/tratamento farmacológico , Penfigoide Gestacional/diagnóstico , Penfigoide Gestacional/terapia , Colestase Intra-Hepática/diagnóstico , Colestase Intra-Hepática/terapia , Colestase Intra-Hepática/complicações , Dermatopatias/diagnóstico , Dermatopatias/terapia , Diagnóstico Diferencial , Prurido/diagnóstico , Prurido/etiologia , Prurido/terapia
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