Assuntos
Criopreservação/métodos , Cabeça do Fêmur/transplante , Cloreto de Sódio , Irrigação Terapêutica/métodos , Preservação de Tecido/métodos , Artroplastia de Quadril , Sangue/microbiologia , Resistência Microbiana a Medicamentos , Cabeça do Fêmur/microbiologia , Humanos , Controle de Infecções/métodos , Lipídeos/efeitos adversos , Pressão , Irrigação Terapêutica/economia , Irrigação Terapêutica/instrumentaçãoRESUMO
60 fresh-frozen bone allografts were contaminated on the operating room floor. No bacterial growth was detected in 5 of them after contamination. The remaining 55 grafts had positive bacterial cultures and were processed with three methods: soaking in saline, soaking in antibiotic solution or washing by high-pressure saline. After high-pressure lavage, the cultures were negative in three fourths of the contaminated allografts. The corresponding figures after soaking grafts in saline and antibiotic solution were one tenth and two tenths, respectively. High-pressure saline cleansing of allografts can be recommended because it improves safety by reducing the superficial bacterial bioburden.
Assuntos
Bactérias/crescimento & desenvolvimento , Cabeça do Fêmur/microbiologia , Cabeça do Fêmur/transplante , Controle de Infecções/métodos , Cloreto de Sódio , Irrigação Terapêutica/métodos , Preservação de Tecido/métodos , Transplante Homólogo , Cefuroxima , Cefalosporinas , Contagem de Colônia Microbiana , Humanos , Controle de Infecções/normas , Pressão , Soluções , Irrigação Terapêutica/normas , Preservação de Tecido/normasRESUMO
Both allogeneic bone grafting and blood transfusion may transmit infections from the donor to the recipient. The most effective means to reduce the risk of infection is careful donor selection and screening of donors for markers of infection. The risk of blood transfusion-transmitted HIV infection in Finland, calculated with the incidence/window period model, is approximately 1:3,300,000. The calculated risk for hepatitis B (HBV) and C (HCV) is 1:217,000 and 1:147,000 donations, respectively. In bone banking we can further reduce the risks by retesting the living donors. Retesting 2 months after donation seems to be sufficient, at least in countries with a low incidence of transplantation-transmitted infections.
