RESUMO
CLINICAL QUESTION: In adults with osteoarthritis of the knee, do conservative management methods such as weight reduction, physical therapy, Tai Chi, non-steroidal anti-inflammatory drugs (NSAIDs), and others provide more and longer pain relief and functionality of the knee, as well as overall well-being, when compared to corticosteroid knee injections? ANSWER: Yes. Although there are limited head-to-head trials directly comparing each alternative method to corticosteroid injections, overall evidence appears to indicate conservative methods as being more effective than injections, especially when considering long-term pain relief and functionality.
Assuntos
Corticosteroides , Tratamento Conservador , Osteoartrite do Joelho , Manejo da Dor , Corticosteroides/administração & dosagem , Adulto , Humanos , Injeções Intra-Articulares , Osteoartrite do Joelho/complicações , Osteoartrite do Joelho/terapia , DorRESUMO
Most cases of malaria in the United States, including the case described below, are due to travelers not taking proper prophylactic medications. With a potentially long incubation period, patients are frequently misdiagnosed (often with viral syndrome or pharyngitis) and correct treatment is delayed. Effective preventative medicines include Malarone, mefloquine, and doxycycline. Chloroquine, a staple of malaria prevention in the past, now has very limited usefulness due to drug resistance.