1.
Chemistry
; 18(35): 10834-8, 2012 Aug 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22786809
RESUMO
"I" did it: An iodine(III)-mediated bromocarbocyclization was elaborated as an efficient tool for the synthesis of oxoindoles. This method is applicable to a variety of structurally different substrates, also with chemically sensitive groups, and gives access to the heterocycles in a regio- and stereoselective fashion. The indole-2-ones obtained can be converted easily into structurally complex target compounds, such as the alkaloid physostigmine.