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1.
J Stroke Cerebrovasc Dis ; 33(1): 107463, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38006768

RESUMO

INTRODUCTION: The intricate relationship between Chagas disease and ischemic stroke remains unclear. Limited evidence exists concerning secondary prophylaxis, etiological diagnosis, and stroke-related determinants. This study aims to discern factors linked to stroke in Chagas disease by contrasting patients with and without a history of ischemic stroke. METHODS: Retrospective data from all outpatient Chagas disease patients from two Brazilian hospitals - one Chagas center and one stroke clinic - were examined. Descriptive analyses were conducted to identify stroke-associated factors. Variables were compared between patients with and without ischemic stroke history. RESULTS: Among 678 subjects, 72 had experienced stroke. Univariate associations with stroke included male gender, heart failure, prior or ongoing alcoholism, electrocardiographic features (non-sinus rhythm, left bundle branch, right bundle branch block, left anterosuperior fascicular block, atrial fibrillation), as well as echocardiographic findings indicative of reduced left ventricular ejection fraction and segmental abnormalities. After logistic regression (multivariate analysis), congestive heart failure, right bundle branch block, left anterosuperior divisional block, and atrial fibrillation retained independent associations. CONCLUSION: In this study, cardiac involvement emerged as the predominant factor correlated with stroke in Chagas disease. While atherosclerosis-related risk factors were prevalent, their influence on ischemic stroke in Chagas disease appeared limited.


Assuntos
Fibrilação Atrial , Cardiomiopatia Chagásica , Doença de Chagas , Insuficiência Cardíaca , AVC Isquêmico , Acidente Vascular Cerebral , Humanos , Masculino , Fibrilação Atrial/diagnóstico , Fibrilação Atrial/epidemiologia , Fibrilação Atrial/complicações , Estudos de Casos e Controles , Estudos Retrospectivos , Volume Sistólico , Bloqueio de Ramo/complicações , Função Ventricular Esquerda , Doença de Chagas/complicações , Doença de Chagas/diagnóstico , Doença de Chagas/epidemiologia , Acidente Vascular Cerebral/diagnóstico por imagem , Acidente Vascular Cerebral/epidemiologia , Fatores de Risco , Insuficiência Cardíaca/diagnóstico , Insuficiência Cardíaca/epidemiologia , Insuficiência Cardíaca/etiologia , AVC Isquêmico/complicações , Eletrocardiografia/efeitos adversos
4.
J Neurovirol ; 28(3): 460-463, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-35678983

RESUMO

Dengue fever has been associated with several neurological complications, cerebellar involvement being among the rarest of them. Here, we describe the case of a 70-year-old female who presented a cerebellar syndrome during the first day of an arboviral infection, posteriorly confirmed as dengue fever. Among the seven other cases in which the relationship between dengue virus and ataxia was reported, only in one cerebellar presentation occurred as early. Onset, course, and prognosis, as well as the adequate investigation and management of these patients, are discussed. While the disease pattern is not better characterized by future studies, differential diagnosis and close follow-up are essential tools for guaranteeing good outcomes.


Assuntos
Ataxia Cerebelar , Doenças Cerebelares , Dengue , Doença Aguda , Idoso , Ataxia Cerebelar/complicações , Ataxia Cerebelar/diagnóstico , Dengue/complicações , Dengue/diagnóstico , Feminino , Humanos
5.
J Electrocardiol ; 50(6): 960-963, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28807354

RESUMO

Low QRS amplitude in V1, with relative three-to-fourfold or greater increase in V2, is considered an indirect sign of right atrium enlargement (Peñaloza-Tranchesi sign). We describe a patient with Peñaloza-Tranchesi sign caused by an ascending aortic aneurysm, with normalization of the QRS complex amplitude in V1 after aortic replacement.


Assuntos
Aneurisma da Aorta Torácica/diagnóstico , Aneurisma da Aorta Torácica/cirurgia , Bioprótese , Implante de Prótese Vascular/métodos , Prótese Vascular , Eletrocardiografia , Idoso , Meios de Contraste , Diagnóstico Diferencial , Ecocardiografia , Feminino , Humanos , Tomografia Computadorizada por Raios X
6.
Acta Cir Bras ; 32(2): 157-167, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-28300878

RESUMO

PURPOSE: To investigate a method for development of surgical skills in medical students simulating venous dissection in surgical ex vivo pig model. METHODS: Prospective, analytical, experimental, controlled study with four stages: selection, theoretical teaching, training and assessment. Sample of 312 students was divided into two groups: Group A - 2nd semester students; Group B - students of 8th semester. The groups were divided into five groups of 12 students, trained two hours per week in the semester. They set up four models to three students in each skill station assisted by a monitor. Teaching protocol emergency procedures training were applied to venous dissection, test goal-discursive and OSATS scale. RESULTS: The pre-test confirmed that the methodology has not been previously applied to the students. The averages obtained in the theoretical evaluation reached satisfactory parameters in both groups. The results of applying OSATS scale showed the best performance in group A compared to group B, however, both groups had satisfactory medium. CONCLUSION: The method was enough to raise a satisfactory level of skill both groups in venous dissection running on surgical swine ex vivo models.


Assuntos
Dissecação/educação , Educação de Graduação em Medicina/métodos , Estudantes de Medicina , Venostomia/educação , Animais , Competência Clínica , Avaliação Educacional , Modelos Anatômicos , Modelos Educacionais , Estudos Prospectivos , Faculdades de Medicina , Suínos
7.
Acta cir. bras ; 32(2): 157-167, Feb. 2017. tab, graf
Artigo em Inglês | LILACS | ID: biblio-837683

RESUMO

Abstract Purpose: To investigate a method for development of surgical skills in medical students simulating venous dissection in surgical ex vivo pig model. Methods: Prospective, analytical, experimental, controlled study with four stages: selection, theoretical teaching, training and assessment. Sample of 312 students was divided into two groups: Group A - 2nd semester students; Group B - students of 8th semester. The groups were divided into five groups of 12 students, trained two hours per week in the semester. They set up four models to three students in each skill station assisted by a monitor. Teaching protocol emergency procedures training were applied to venous dissection, test goal-discursive and OSATS scale. Results: The pre-test confirmed that the methodology has not been previously applied to the students. The averages obtained in the theoretical evaluation reached satisfactory parameters in both groups. The results of applying OSATS scale showed the best performance in group A compared to group B, however, both groups had satisfactory medium. Conclusion: The method was enough to raise a satisfactory level of skill both groups in venous dissection running on surgical swine ex vivo models.


Assuntos
Animais , Estudantes de Medicina , Venostomia/educação , Dissecação/educação , Educação de Graduação em Medicina/métodos , Faculdades de Medicina , Suínos , Estudos Prospectivos , Competência Clínica , Modelos Educacionais , Avaliação Educacional , Modelos Anatômicos
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