Mandibular cortical bone evaluation on cone beam computed tomography images of patients with bisphosphonate-related osteonecrosis of the jaw.

OBJECTIVES: The objective of this study was to develop a technique for detecting cortical bone dimensional changes in patients with bisphosphonate-related osteonecrosis of the jaw (BRONJ). STUDY DESIGN: Subjects with BRONJ who had cone-beam computed tomography imaging were selected, with age- and gender-matched controls. Mandibular cortical bone measurements to detect bisphosphonate-related cortical bone changes were made inferior to mental foramen, in 3 different ways: within a fixed sized rectangle, in a rectangle varying with the cortical height, and a ratio between area and height. RESULTS: Twelve BRONJ cases and 66 controls were evaluated. The cortical bone measurements were significantly higher in cases than controls for all 3 techniques. The bone measurements were strongly associated with BRONJ case status (odds ratio 3.36-7.84). The inter-rater reliability coefficients were high for all techniques (0.71-0.90). CONCLUSIONS: Mandibular cortical bone measurement is a potentially useful tool in the detection of bone dimensional changes caused by bisphosphonates.

Evaluating craniofacial asymmetry with digital cephalometric images and cone-beam computed tomography.

INTRODUCTION: The aim of this study was to evaluate craniofacial asymmetry by using 2-dimensional (2D) posteroanterior cephalometric images, 3-dimensional cone-beam computed tomography (CBCT), and physical measurements (gold standard). METHODS: Ten dry human skulls were assessed, and radiopaque markers were placed on 17 skeletal landmarks. Twenty linear measurements were taken on each side to compare the right and left sides and to compare these measurements with the physical measurements made with a digital caliper. To acquire the 2D posteroanterior radiographs, an Extraoral Phosphor Storage Plate (Air Techniques, Chicago, Ill) was used as the image receptor with a Eureka x-ray-Duocon Machlett unit (Machlett Laboratores, Chicago, Ill). Three-dimensional imaging data were acquired from a CB MercuRay (Hitachi Medical, Tokyo, Japan). RESULTS: On average, the right side was larger than the left for most of the 20 distances evaluated in the digital 2D and the CBCT images, and there was poor agreement between the digital 2D images and the physical measurements (kappa = 0.0609) and almost perfect agreement (kappa = 0.92) between the CBCT and physical measurements when individual measurements were considered. CONCLUSIONS: Human skulls, with no apparent asymmetry, had some differences between the right and left sides, with dominance for the right side but with no clinical significance. CBCT can better evaluate craniofacial morphology when compared with digital 2D images.

Disk position and the bilaminar zone of the temporomandibular joint in asymptomatic young individuals by magnetic resonance imaging.

OBJECTIVE: The purpose was to study the disk position of the temporomandibular joint (TMJ) in young individuals without any clinical signs or symptoms or history of internal derangement or degenerative joint disease and to study the features of the bilaminar zone of the TMJ in sagittal magnetic resonance (MR) images and the behavior of the bilaminar zone during jaw opening. STUDY DESIGN: MR imaging examinations of 80 TMJs of 40 symptom-free healthy subjects (20 women and 20 men) with a mean age of 26.9 years formed the basis of this study. RESULTS: In 33 of the 40 symptom-free subjects (82.5%), there was a normal relationship between disk and condyle at occlusion, whereas 5 individuals had unilateral disk displacement and 2 had bilateral disk displacement. The superior part of the bilaminar zone could be identified in all of the 40 symptom-free subjects. The inferior band of the bilaminar zone was identified bilaterally in 57.5% of individuals and unilaterally in 20%. In 9 subjects, the inferior band of the bilaminar zone could not be identified in any of the TMJs. CONCLUSIONS: Disk displacement of the TMJ occurred in approximately 20% of the young individuals in this sample. The use of both sagittal and oblique coronal MR images is of importance for classification of the position of the disk in that the oblique coronal imaging plane rendered significant complementary information to that of the sagittal images. The identification of both the superior and the posterior band of the bilaminar zone must be considered new information. The superior band remained consistently in contact with the fossa at the open-mouth position.