RESUMO
Background: This meta-analysis was conducted to evaluate the effect of fractional flow reserve (FFR) on clinical outcomes after coronary artery bypass grafting (CABG). Methods: Five online databases were searched for studies that (1) enrolled patients who underwent isolated CABG or CABG with aortic valve replacement and (2) demonstrated the effect of an FFR-guided strategy on major adverse cardiac events (MACE) after surgery based on a randomized controlled trial or adjusted analysis. MACE included cardiac death, acute myocardial infarction (MI), and repeated revascularization. The primary outcomes were all MACE outcomes and a composite of all-cause death and MI, and the secondary outcomes were the individual MACE outcomes. Publication bias was assessed using a funnel plot and the Egger test. Results: Six articles (3 randomized and 3 non-randomized studies: n=1,027) were selected. MACE data were extracted from 4 studies. The pooled analyses showed that the risk of MACE was not significantly different between patients who underwent FFR-guided CABG and those who underwent angiography-guided CABG (hazard ratio [HR], 0.80; 95% CI, 0.57-1.12). However, the risk of the composite of death or MI was significantly lower in patients undergoing FFR-guided CABG (HR, 0.62; 95% CI, 0.41-0.94). The individual MACE outcomes were not significantly different between FFR-guided and angiography-guided CABG. Conclusion: FFR-guided CABG might be beneficial in terms of the composite outcome of death or MI compared with angiography-guided CABG although data are limited.
RESUMO
Recent outbreaks and the worldwide spread of COVID-19 have challenged mankind with unprecedented difficulties. The introduction of autonomous disinfection robots appears to be indispensable as consistent sterilization is in desperate demand under limited manpower. In this study, we developed an autonomous navigation robot capable of recognizing objects and locations with a high probability of contamination and capable of providing quantified sterilization effects. In order to quantify the 99.9% sterilization effect of various bacterial strains, as representative contaminants with robots operated under different modules, the operating parameters of the moving speed, distance between the sample and the robot, and the radiation angle were determined. We anticipate that the sterilization effect data we obtained with our disinfection robot, to the best of our knowledge, for the first time, will serve as a type of stepping stone, leading to practical applications at various sites requiring disinfection.
Assuntos
COVID-19 , Robótica , Inteligência Artificial , Desinfecção , Humanos , SARS-CoV-2 , EsterilizaçãoRESUMO
Temperature measurement is very important for thermal control, which is required for the advancement of mechanical and electronic devices. However, current temperature sensors are limited by their inability to measure curved surfaces. To overcome this problem, several methods for printing flexible substrates were proposed. Among them, electrohydrodynamic (EHD) inkjet printing technology was adopted because it has the highest resolution. Since EHD inkjet printing technology is limited by the type of ink used, an ink with temperature-sensing properties was manufactured for use in this printer. To confirm the applicability of the prepared ink, its resistance characteristics were investigated, and the arrangement and characteristics of the particles were observed. Then, the ink was printed using the EHD inkjet approach. In addition, studies of the meniscus shapes and line widths of the printed results under various conditions confirmed the applicability of the ink to the EHD inkjet printing technology and the change in its resistance with temperature.
