Vitamin D, race, and experimental pain sensitivity in older adults with knee osteoarthritis.

OBJECTIVE: Low circulating serum levels of 25-hydroxyvitamin D (referred to hereafter as vitamin D) have been correlated with many health conditions, including chronic pain. Recent clinical practice guidelines define vitamin D levels <20 ng/ml as deficient and levels of 21-29 ng/ml as insufficient. Vitamin D insufficiency, including the most severe levels of deficiency, is more prevalent in black Americans. Ethnic and race group differences have been reported in both clinical and experimental pain, with black Americans reporting increased pain. The purpose of this study was to examine whether variations in vitamin D levels contribute to race differences in knee osteoarthritis pain. METHODS: The sample consisted of 94 participants (74% women), including 45 blacks and 49 whites with symptomatic knee osteoarthritis. Their average age was 55.8 years (range 45-71 years). Participants completed a questionnaire on knee osteoarthritis symptoms and underwent quantitative sensory testing, including measures of sensitivity to heat-induced and mechanically induced pain. RESULTS: Blacks had significantly lower levels of vitamin D compared to whites, demonstrated greater clinical pain, and showed greater sensitivity to heat-induced and mechanically induced pain. Low levels of vitamin D predicted increased experimental pain sensitivity, but did not predict self-reported clinical pain. Group differences in vitamin D levels significantly predicted group differences in heat pain and pressure pain thresholds at the index knee and ipsilateral forearm. CONCLUSION: These data demonstrate that race differences in experimental pain are mediated by differences in the vitamin D level. Vitamin D deficiency may be a risk factor for increased knee osteoarthritis pain in black Americans.

Linking depressive symptoms and functional disability in late life.

We hypothesized that the relationship of depressive symptoms to functional disability might be mediated by cognitive processes such as memory and problem-solving. The study sample consisted of 147 community-dwelling older adults (mean age = 74.0 years, SD = 5.9). In regression models that included terms for age, gender, and years of education, depressive symptoms were significantly inversely associated with two performance-based measures of functioning: everyday problems test (beta = -0.15, p = 0.04) and observed tasks of daily living (beta = -0.14, p = 0.02). When memory and problem-solving ability were added to the model, the relationship of depressive symptoms with function was attenuated. A structural equation model based on our conceptual framework revealed that both memory and problem-solving abilities were important mediators in the relationship of depressive symptoms and functional disability. The results suggest that intervention studies intended to limit functional disability secondary to depression among older adults may need to consider the effect of depression on cognition.

Measuring behavioral and mood disruptions in nursing home residents using the Minimum Data Set.

The Minimum Data Set (MDS) is a standardized assessment tool designed to provide a comprehensive biopsychosocial assessment of medical, behavioral, and cognitive status of nursing home residents. This pilot study examined the relationships of three MDS subscales--cognition, depressive symptoms, and behavioral disruptions--to other measures of the same domains (e.g., diagnosed dementia and depression and caregiver ratings on the Revised Memory and Behavior Problems Checklist [RMBPC]). The sample consisted of 135 nursing home residents with a mean age of 84 years. Based on the MDS, there was a high prevalence of cognition-related behaviors but a low prevalence of disruptive and depressed behaviors. The prevalence rates were substantially different according to the RMBPC. In addition, most of the MDS subscales failed to differentiate between residents with and without diagnosed dementia and depression, whereas caregiver ratings on the RMBPC did. The MDS and RMBPC subscales were modestly related but only in residents without dementia. These findings raise questions about the validity of the MDS in measuring nursing home residents' behavior, especially depressive and disruptive behaviors. Thus, caution should be employed in using the MDS as a sole outcome measure for these behaviors, and the use of multiple measures is suggested.

Pain in nursing home residents. Comparison of residents' self-report and nursing assistants' perceptions. Incongruencies exist in resident and caregiver reports of pain; therefore, pain management education is needed to prevent suffering.

Physical pain is a significant problem for many older adults, and as many as 83% of nursing home residents reportedly have pain. Unrelieved pain has consequences for elderly individuals' physical and mental health, rehabilitation, and quality of life. Evidence suggests, however, that pain is underdetected and poorly managed among older adults. This may be due, in part, to lack of congruence between patients' and caregivers' perceptions of pain. Thus, the purpose of this study was to investigate: the prevalence, location, and intensity of residents' self-rated and nursing assistants' (NA) rated pain; the congruence between residents' and NAs' ratings of pain; and resident-based and NA-based correlates of congruent and incongruent pain ratings. Participants in this study were 45 nursing home resident-NA dyads. The results indicated 49% of residents stated they experienced pain in the past week, but NAs reported that 36% of residents experienced pain during the same time interval. There was no significant association between residents' self-ratings and NAs' ratings of pain. Of the 45 paired ratings, residents and NAs were congruent in 37.7% of cases and incongruent in 62.2% of cases. Incongruent ratings included both underdetection (37.8%) and overreporting (24.4%) by the NAs. Only residents' self-rated affect (e.g., depression, well-being) was significantly associated with whether their pain was congruently assessed, underdetected, or overreported. Depression was highest in those for whom pain was not perceived by the NAs and well-being was highest in those residents who denied pain but for whom NAs reported pain. Caregiver characteristics (e.g., age, education, work experience) were not significantly associated with pain congruence outcomes. These findings illustrate the complexities of assessing pain in older adults, and the need to include nursing assistants (NAs) in educational programs focusing on managing pain in elderly nursing home residents.

The prevalence of prayer as a spiritual self-care modality in elders.

The purpose of this cross-sectional, descriptive study was to (a) investigate whether elders report using prayer as a coping strategy, (b) examine the frequency and type of spiritual treatment modalities used by elders, and (c) determine if there is a relationship between spiritual treatment modalities and coping in this population. The sample consisted of 50 community-dwelling elders with a mean age of 74 years. Descriptive findings indicate that 96% of elders use prayer to cope with stress based on the Jalowiec Coping Scale. Women and Blacks used prayer to cope with stress significantly more often than did men and Whites. The most frequently reported alternative treatment modality was prayer (84%). The total number of spiritual treatment modalities reported was significantly correlated with the frequent use of more positive coping styles.

Daily life in very old age: everyday activities as expression of successful living.

The goals of this article are (a) to describe the daily life of the very old in terms of frequency, duration, variety, and social and physical contexts of activities, and (b) to examine the effects of background variables (e.g., age, sex, residential and marital status, income, and education) on late life activity engagement. A representative sample of 516 adults aged 70-105 was interviewed about their activities using the Yesterday Interview. In contrast to most research on activity engagement, this measurement approach allows for assessment of both the type and context of activities engaged in during the day preceding the interview. The results indicated high frequencies of obligatory activities but also showed substantial time spent in discretionary activities, with television viewing occupying most of the participants' leisure time. Most activities were done alone and at home. In bivariate and multiple regression analyses, age and residential status had the strongest association with activity frequency, duration, and variety; the oldest-old and those residing in long-term care facilities had lower levels of activity engagement. Results are discussed in terms of their relevance for successful aging.

Analgesic drug prescription and use in cognitively impaired nursing home residents.

BACKGROUND: Prior research has documented the high prevalence of pain in elderly adults and the difficulties associated with properly assessing and treating pain in elders with cognitive impairment. OBJECTIVES: To investigate the prescription and administration of analgesic medications to treat pain in cognitively impaired nursing home residents. METHOD: The current sample consisted of 339 nursing home residents (295 women and 44 men) with a mean age of 87 years (range 66-104). Forty-six percent of the sample had diagnosed cognitive impairment, and 55% had at least one diagnosed painful condition. Data for this correlational study were drawn from four nursing homes in Western Pennsylvania. The Multidimensional Observation Scale for Elderly Subjects was used to assess behavioral indicators of cognitive impairment, and chart review was used to obtain demographic, medication, and diagnostic data. RESULTS: The results indicated that cognitively impaired nursing home residents are prescribed and administered significantly less analgesic medication, both in number and in dosage of pain drugs than their more cognitively intact peers. In multiple regression analyses holding the presence of painful conditions constant, more disoriented and withdrawn residents were prescribed significantly less analgesia by physicians; more disoriented, withdrawn, and functionally impaired residents were administered significantly less analgesia by nursing staff. CONCLUSIONS: The findings highlight the difficulties of assessing pain in cognitively impaired elders and the lack of knowledge among health care providers about effective pain management.

Predicting health care utilization in the very old. The role of physical health, mental health, attitudinal and social factors.

The purpose of this paper is to predict health care utilization in the very old from a combination of individual-based factors such as physical and mental health, health attitudes and beliefs, sociodemographic characteristics, and life circumstances. This study was conducted within the context of the Berlin Aging Study (BASE). Higher use of medications was most strongly predicted by more medical diagnoses, better cognitive status, and health attitudes. Physician contact was only weakly predicted by physical health variables, hypochondriasis, and living alone. In contrast, living alone was the greatest predictor of the utilization of increased levels of caregiving services, while having children nearby served as a protective factor against the need for more formal caregiving services. These results show that utilization of health care depends on interaction between physical and mental health, attitudinal, and social factors.

Screening an elderly population for verifiable adverse drug reactions. Methodological approach and initial data of the Berlin Aging Study (BASE).

Older adults are known to carry the largest risk for potential adverse drug reactions (ADR) due to the increased number of diseases and concurrent drug therapies. Prevalence rates of the most frequently used drugs in this population have already been evaluated, but the actual rates of specific drug-related risks (e.g., renal dysfunction) have not. Precise estimates of specific ADR risks rely on careful evaluation of the complete drug regimen for potential adverse effects, especially for elderly subjects. In addition, evaluations of manifest ADR have generally been based on reviews of individual medical records of self-reported symptoms. Systematic screening of a representative sample of elders for verifiable potential ADR has not been performed to date and is methodologically challenging. However, the present study attempts to assess both the prevalence of explicitly defined risks for known ADR and the corresponding co-occurrence of laboratory parameter alterations using a new approach. Initial findings are reported for a nearly-representative, age and sex stratified sample of 70 to 100+ year old subjects (n = 336) who participated in the Berlin Aging Study (BASE). Analyses focused on adverse drug effects on fluid and electrolyte balance and renal function. The results indicated an overall prevalence rate of 50% for selected ADR risks and a rate of 26% for the co-occurrence of corresponding laboratory alterations. By taking age into account, preliminary multivariate analyses did not support the hypothesis of increasing ADR susceptibility with advancing age.

The relationship of antipsychotic drug use, behavior, and diagnoses among nursing home residents.

Nursing homes have been criticized for frequent use and possible misuse of psychoactive agents. These issues are of clinical concern and policy relevance, especially since the passage of the Omnibus Budget Reconciliation Act (OBRA) of 1987. Using a sample of 419 residents, the authors examined the relationships among antipsychotic drug (AP) use, behavior, and mental health diagnoses. Only 23.2% of the residents were administered APs on a routine and/or "as-needed" basis. Based on the Multidimensional Observation Scale for Elderly Subjects (MOSES) ratings, AP users were more irritable, disoriented, and withdrawn than were nonusers. Also, AP users demonstrated agitated behaviors more frequently. Notably, AP users and nonusers differed significantly in terms of documented mental health diagnoses. Among AP users, 70.1% had documented dementia, 8.3% were psychotic or had other psychiatric disorders, and 21.6% had no mental health diagnoses. In contrast, the majority of nonusers had no mental health disorders. Logistic regression revealed that diagnostic factors, frequency of agitation, level of withdrawal, and marital status were significant predictors of AP use.

Behavior management training for nurse aides: is it effective?

Nursing assistants are responsible for 80% to 90% of all direct resident care in nursing homes, but are the least well trained personnel. Even with currently mandated training, specific skills to meet mental health needs are not taught. Training in behavior management skills prepares aides to observe and respond to problem behaviors more effectively. Aides view their own use of skills as increased by this training. To be practically useful, mental health training programs for nurse aides should be provided by professional personnel in brief, concrete, self-contained units that model the skills they present.