1.
Org Lett
; 2(20): 3197-9, 2000 Oct 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11009380
RESUMO
1,3-Diol synthons, protected as acetonides or benzylidene acetals, may be synthesized efficiently from homoallylic alcohols and acetone or benzaldehyde by oxymercuration of the derived hemiketals and hemiacetals with HgClOAc. The use of catalytic amounts of Yb(OTf)(3) is crucial to the success of the reaction, which was determined to be reversible.