1.
Cancer
; 68(8): 1691-3, 1991 Oct 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-1913509
RESUMO
An ocular toxic reaction presenting as conjunctivitis or keratitis develops in a significant number of patients who are treated with high-dose cytosine arabinoside (ara-C). Although eye drops containing glucocorticoid reportedly decrease the incidence, they do not totally eliminate this side effect. In comparing this technique with artificial tears, both were found to be equally effective. The primary mechanism by which eye drops decrease ocular toxic reactions associated with high-dose ara-C is presumably due to dilution of intraocular concentrations of ara-C.
Assuntos
Conjuntivite/prevenção & controle , Citarabina/efeitos adversos , Dexametasona/uso terapêutico , Ceratite/prevenção & controle , Leucemia Mieloide Aguda/tratamento farmacológico , Prednisolona/análogos & derivados , Adulto , Idoso , Conjuntivite/induzido quimicamente , Método Duplo-Cego , Feminino , Humanos , Ceratite/induzido quimicamente , Masculino , Pessoa de Meia-Idade , Soluções Oftálmicas , Prednisolona/uso terapêutico
2.
Ann N Y Acad Sci
; 277(00): 522-32, 1976.
Artigo
em Inglês
| MEDLINE
| ID: mdl-1069561