1.
Fitoterapia
; 75(7-8): 712-7, 2004 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15567248
RESUMO
Thaliblastine exhibits dose dependent cytotoxic effect on HL-60, HL-60/DOX, RHE and HD-MY-2 leukemia cells. Additionally, typical for apoptosis oligonucleosomal DNA fragmentation could be detected in leukemia cells treated with thaliblastine. Moreover, an MDR-phenotype reversing effect of thaliblastine was also identified.