1.
J Org Chem
; 88(15): 10828-10835, 2023 Aug 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37471258
RESUMO
A novel and practical approach to access saturated ketones from unsaturated ketone derivatives via a CS2/t-BuOK system in dimethyl sulfoxide (DMSO) is reported. The in situ generation of xanthate salt through the reaction of carbon disulfide and potassium tert-butoxide is essential to this transformation. Deuterium-labeling experiments demonstrated that DMSO can act as a hydrogen donor.