Symptoms of dry eye and recurrent erosion syndrome after refractive surgery.

PURPOSE: To determine the incidence and severity of patient complaints typical of dry eye and recurrent erosion syndrome after excimer laser refractive surgery and to compare the incidence of these symptoms after photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK). SETTING: Outpatient university practice. METHODS: A questionnaire was mailed to 1731 patients who had had primary myopic PRK or LASIK at least 6 months previously. Questions were designed to determine the incidence and character of ocular dryness and recurrent erosion symptoms and their impact on patient satisfaction and willingness to have surgery again. Responses from PRK and LASIK patients were compared. RESULTS: Responses from 231 PRK patients and 550 LASIK patients revealed an incidence of dryness symptoms in 43% and 48%, respectively (P >.05). Soreness of the eye to touch was reported by 26.8% and 6.7%, respectively (P <.0001). Sharp pains occurred in 20.4% of PRK patients and 8.0% of LASIK patients (P =.0001). Complaints of the eyelid sticking to the eyeball occurred in 14.7% and 5.6%, respectively (P =.0001). All symptoms occurred predominantly on waking. Frequency of eyelid sticking (P <.0005) and sharp pain (P <.005) symptoms, as well as severity of sharp pain symptoms (P <.0001), were significantly greater in PRK patients than in LASIK patients. On a scale of 0 to 10 (10 high), median overall patient satisfaction with surgery was 9 in both groups. Soreness of the eyelid to touch occurred significantly more frequently among patients with symptoms of sharp pains on waking (P <.001) and the sensation of the eyelid sticking to the eyeball (P <.001). Patients with 1 or more symptoms were twice as likely as asymptomatic patients to have a satisfaction score of less than 8 (P <.001). CONCLUSIONS: Ocular dryness symptoms occurred commonly after PRK and LASIK. Symptoms suggestive of mild recurrent erosions included sharp pains, the sensation of the eyelid sticking to the eyeball, and soreness of the eyelid to touch, a previously unrecognized symptom of this condition. These symptoms occurred commonly after excimer laser procedures but were significantly more common, more severe, and more prolonged after PRK. The presence of these symptoms had a significant effect on patient satisfaction.

Quantitative topographic irregularity as a predictor of spectacle-corrected visual acuity after refractive surgery.

PURPOSE: To evaluate a new topographic index called topographic irregularity as a quantitative predictor of corrected vision after refractive surgery. METHODS: We defined topographic irregularity as the summed difference at all points between a topographic refractive corneal power map and its best-fit spherocylinder. We prospectively studied 107 eyes of 107 patients 3 months after a variety of refractive procedures. Topographic irregularity was calculated from topographic maps, and the correlation between topographic irregularity and spectacle-corrected visual acuity was determined using both high-contrast and low-contrast acuity charts. This correlation was compared with correlations for the surface regularity index and the surface asymmetry index. Next, we analyzed 54 of these topographic maps to create a regression scale relating surface regularity index, surface asymmetry index, and topographic irregularity to predict spectacle-corrected visual acuity. This scale was then used to predict spectacle-corrected visual acuity on the remaining 53 postoperative patients. RESULTS: The correlation of topographic irregularity with spectacle-corrected visual acuity (R(2) =.36) was comparable to the correlation for the surface regularity index (R(2) =.36) and stronger than for the surface asymmetry index (R(2) =.11) when spectacle-corrected visual acuity was measured with high-contrast eye charts. Topographic irregularity correlated more strongly with spectacle-corrected visual acuity (R(2) =.42) than either the surface regularity index (R(2) =.28) or the surface asymmetry index (R(2) =.14) when spectacle-corrected visual acuity was measured with low-contrast eye charts. Using the regression scale, prediction of high-contrast and low-contrast spectacle-corrected visual acuity from topographic irregularity was superior to or comparable to predictions using the surface regularity index and the surface asymmetry index. CONCLUSIONS: Topographic irregularity has a closer correlation with spectacle-corrected visual acuity than existing topographic indexes. Topographic irregularity is also an accurate predictor of spectacle-corrected visual acuity and may be a more sensitive tool for evaluating postoperative visual performance than current topographic measures.

Long-term visual outcome of ocular hypotension after thermosclerostomy.

Maximum intraocular pressure reduction is often the goal of glaucoma filtering procedures. To evaluate whether surgically induced ocular hypotension adversely affects visual acuity, we reviewed the visual outcome of 87 eyes of 67 patients who had undergone thermosclerostomy with follow-up of at least two years. Final visual acuity was compared in three groups on the basis of postoperative intraocular pressure level (< or = 10.0 mm Hg; > 10.0 mm Hg and < or = 21.0 mm Hg; and eyes that did not consistently fit solely in either group [mixed]). Average loss in visual acuity measured 1.8 +/- 3.0, 2.2 +/- 2.9, and 1.2 +/- 2.1 Snellen lines, respectively (P = .542). These data suggest that hypotensive eyes are not at greater risk for visual loss after glaucoma filtering procedures compared to normotensive eyes.