Non-coaxial deformation of foreland basement involved in a fold-and-thrust belt: a strain partitioning approach to the Eastern Variscan orogen.

The general SW-NE course of the Variscan orogen in Europe is abruptly bent to the N-S course at its eastern margin, where an oblique convergence occurred. The main suture in this part of the Variscan orogenic belt is called the Moldanubian Thrust, characterized by a dominant dextral strike-slip kinematics and a minor thrust component. The deep level of erosion and the good exposure of this structure allowed us to study the mechanisms of oblique convergence and the incorporation of the foreland basement into the orogenic belt. The combination of small-scale structures with the anisotropy of magnetic susceptibility studies allowed the recognition of two deformations in the studied rocks: dextral simple shearing and drag folding. Due to oblique convergence, the deformations induced by this mechanism were non-coaxial; therefore, their contributions can be easily distinguished. Finally, an overturned, almost recumbent large-scale synformal fold structure in the footwall and an antiformal structure in the hanging wall of the Moldanubian Thrust were formed. These two folds can be interpreted as structures formed by dragging along the Moldanubian Thrust. The previously described sinistral simple shearing in the upper limb of the synform resulted from the original dextral strike-slip shearing, which was overturned during progressive deformation.

[Decrease in cardiovascular disease mortality in the Czech Republic from 1984 to 1993 and its possible causes]. / Pokles úmrtnosti na kardiovaskulární onemocnení v Ceské republice v období 1984-1993 a jeho mozné príciny.

BACKGROUND: The objective of the investigation was to evaluate the ten-year development of the cardiovascular mortality rate in two population groups in the age bracket from 25 to 64 years, i.e. in subjects living in six districts which participated in the international WHO project MONICA and in the population of the whole Czech Republic. METHODS AND RESULTS: Data on the mortality rate in 1984-1993 for the age group from 25-64 years were provided by the Institute of Health Information and Statistics, information on the prevalence of risk factors was obtained in three cross-sectional studies implemented in six districts as part of the MONICA project in 1985, 1988 and 1992. In the mortality rate per 100,000 population in the six districts the following changes were revealed (in parentheses the values for 1984 and 1993 are given): men - a statistically significant declining trend in the from all caused mortality (849.3-742.5; p < 0.001) and cardiovascular mortality (367.2-280.4; p < 0.001) and cerebrovascular mortality (69.7-44.8; p < 0.001). In the mortality from ischaemic heart disease (215.7-170.6; ns) a declining trend was not recorded. In women aged 25-64 years in the six districts there was a statistically significant decline of the mortality from all caused (359.5-322.1; p < 0.001), the cardiovascular mortality (115.6-100.6; p < 0.001) and cerebrovascular mortality (31.1-23.6; p < 0.001). The mortality from ischaemic heart disease did not change (49.2-48.8; ns). In the population of the Czech Republic in men the following were detected: a drop of the from all caused mortality (907.1-784.8; P < 0.001), the cardiovascular mortality (383.5-308.4; p < 0.001) and cerebrovascular mortality (76.5-55.3; p < 0.001). Also in women of the Czech Republic a decline of the mortality from all caused was recorded (390.1-328.5; p < 0.001), the cardiovascular mortality (135.3-103.8; p < 0.001), ischaemic heart disease (58.0-48.6; p < 0.001) and cerebrovascular mortality (43.5-27.4; p < 0.001). In 1990 an increased cardiovascular mortality was recorded in men different from the trend during 1984-1993, statistically significant in the Czech Republic (p < 0.05) and in the six districts (p < 0.05). The reasons of this trend are not clear. The role of health services in the mortality drop is not clear, although available data indicate their improvement. Favourable changes were found in risk factors: during the period from 1985-1992 the prevalence of hypercholesterolaemia declined significantly in men and women, the prevalence of hypertension in women and the prevalence of smoking in men declined in the six districts. From nationwide data ensues that after 1989 significant changes occurred in the diet of the Czech population. The meat consumption declined by 1993 by 13%, the milk and dairy product consumption by 26.8% the butter consumption by 43.6% the consumption of vegetable fats increased by 16%, of vegetables by 8%, tropical fruit by 43.2%. These changes probably had an impact on the cholesterol level and BMI of the Czech population. CONCLUSIONS: In the declining cardiovascular mortality trend during 1984-1993 the following may have participated: improved medical care, dietary changes, improvement of the risk profile and other, in particular socioeconomic factors. With regard to the close temporal association of the investigated changes it may be assumed that this development is at least partly associated with changes of the political and economic position in the Czech Republic after 1989.

Myocardial Infarction Register in MONICA-Czechoslovakia Centre.

In 1984, 802 coronary events (age 25-64) were registered in six MONICA areas in Czechoslovakia. According to the MONICA study criteria, 63% of these coronary events in males and 51% in females were confirmed as definite myocardial infarction (MI), 26% of events in both males and females as possible MI, 5% of events in males and females were fetal cases with insufficient data, and 6% of events in males and 18% in females were not confirmed as MI (MONICA diagnostic category = 4). Age-standardized annual attack rates of MI per 100,000 population (age 35-64) were 510.4 for males and 99.3 for females. Age-standardized annual incidence rates (first ever MI) per 100,000 population (age 35-64) were 387.4 for males and 89.7 for females. 28-day case fatality was 33.3% in males and 31.5% in females. Of all deaths occurring within 28 days, 75.8% in males and 69.2% in females occurred during the first 24 hours. Of all coronary deaths, 38.5% of males and 64.1% of females died in hospital or other institution.