RESUMO
A clinical case of cutaneous T-cell lymphoma is presented in this paper - Mycosis fungoides, a tumorous stage that developed in a patient who suffered as a result of the Chornobyl accident. The most likely development of this di- sease is due to the influence of the radiation factor, which led to the affection of lymphoid cells. This disease has characteristic staging with a typical morphological pattern only in later stages, therefore, the diagnosis usually occurs in evident clinical and histological changes of the mycotic and tumorous stages, when treatment is ineffec- tive. The features of the disease and treatment are described.
Assuntos
Acidente Nuclear de Chernobyl , Socorristas , Linfoma Cutâneo de Células T/patologia , Micose Fungoide/patologia , Lesões por Radiação/patologia , Neoplasias Cutâneas/patologia , Diagnóstico Tardio , Dexametasona/uso terapêutico , Feminino , Humanos , Linfoma Cutâneo de Células T/diagnóstico , Linfoma Cutâneo de Células T/etiologia , Linfoma Cutâneo de Células T/terapia , Pessoa de Meia-Idade , Micose Fungoide/diagnóstico , Micose Fungoide/etiologia , Micose Fungoide/terapia , Estadiamento de Neoplasias , Doses de Radiação , Exposição à Radiação/efeitos adversos , Lesões por Radiação/diagnóstico , Lesões por Radiação/etiologia , Lesões por Radiação/terapia , Pele/patologia , Pele/efeitos da radiação , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/etiologia , Neoplasias Cutâneas/terapia , Sobreviventes , Terapia UltravioletaRESUMO
Objective - study of the features of Trichomonas vaginalis invasion in pregnant women and newborns. The cultures of Trichomonas isolated from a pregnant woman, her newborn girl, as well as amniotic fluid were examined. The ultrastructure of the cells was studied using a TEM-125K microscope equipped with a SAI-01A system (SELMI), using a DX 2 CCD camera and the KAPPA software package. The verification of STI pathogens was carried out by PCR, in particular, Trichomonas tenax and Pentatrichomonas hominis were identified by experimental original primers that were developed using real-time PCR (PCR-RT). The invasion of Trichomonas vaginalis of the genital tract of a newborn girl, amniotic fluid and amniotic membrane is characterized clinically and instrumentally. We proved the possibility of Trichomonas vaginalis invasion of newborn children not only during the passage of the child through the infected birth canal, but also due to a defect in the fetal membranes with the development of chorioamnionitis, followed by infection of the amniotic fluid and possible infection of the fetus.
