[The functional status of the thyroid system in those irradiated as a consequence of the accident at the Chernobyl Atomic Electric Power Station (based on screening study data)]. / Funktsional'nyi stan tyreoïdnoï systemy u oprominenykh vnaslidok avariï na ChAES (za danymy skryninhovoho doslidzhennia).

A screening study was made of functional indices for the status of the thyroid system in 1097 persons who took part in the elimination of the effects of the Chernobyl accident (PChAEE) during the "iodine" and "non-iodine" periods of irradiation. In 94.6% of the "iodine" period PChAEE, the basal levels of the thyroid-stimulating hormone (TSH) were in the normal range, 4.79% displayed a rise in the parameter. 90.06% of the "non-iodine" period had normal range TSH, 8.77% exhibited augmented levels. 94.68% of the "iodine" period PChAEE showed normal range for the basal levels of free thyroxin, in 3.72% there was a rise, in 1.6% a decrease in the values. Among the examinees of the "non-iodine" period, the levels of free thyroxin were within normal range in 92%, above norm in 5%, decreased in 3%. The level of antibodies to thyroglobulin in 86.38% of the "iodine" period examinees was in the normal range, in 90.99% of the "non-iodine" period it was also normal. There were no statistically significant differences suggesting effects of radiation factors of the "iodine" period of irradiation on the functional indices for the hypophysis-thyroid system during the first 7 years following irradiation.

[The structural-functional status of the thyroid in patients with nodular goiter evacuated from the 30-kilometer zone of the Chernobyl Atomic Electric Power Station]. / Strukturno-funktsional'nyi stan shchytovydnoï zalozy khvorykh na vuzlovyi zob, evakuiovanykh iz 30-kilometrovoï zony ChAES.

An analysis was performed of results of ultrasonic and hormonal investigations in 239 patients with nodular goiter revealed in a screening-type clinical and laboratory examination of the 3371 persons evacuated from the 30-km zone of ChNPP, at their ages randing between 18 to 68 years. In 84.20% of patients in the group who took part in the elimination of effects of the Chernobyl accident (PEEA)--"PEEA + the evacuated"--the diameter of the nodules did not exceed 1 cm, in 6.1% it ranged from 1 to 2 cm, and in 13.41% it exceeded 2 cm. Distribution of nodules in the group "the evacuated" did not differ much from that in the above group. In 20% of patients with nodular goiter, there were functional disturbances concurrent with the autoimmune processes. No effects were detected of small doses of extra irradiation on the pattern of structural-and-functional indices in patients with nodular goiter evacuated from the 30-km zone of ChNPP who took part in EEA.

[The effect of factors in the accident at the Chernobyl, Atomic Electric Power Station on the development of nodular goiter in the immediate postirradiation period]. / Vplyv chynnykiv avariï na ChAES na rozvytok vuzlovoho zobu v naiblyzhchyi pislia oprominennia period.

With the purpose of studying effects of a complex of factors of Chernobyl Atomic Power Plant breakdown on evolution of nodular goiter, an analysis was carried out of clinical and laboratory evaluation of 6572 individuals (3549 men and 3023 women) who had taken part in the elimination of aftermath of Chernobyl accident, with regard to sex, dose and length of time during which the above individuals were exposed to radiation. Duration of exposure did not appear to affect nodular goiter rates either in men (7.92% in liquidators of "iodine" period and 8.19% among those of "noniodine" period of irradiation, or women (17.31% and 24.66% respectively). Results of studies made 5-7 years after the Chernobyl accident did not show relationship between incidence rate of nodular goiter and dose of radioactive irradiation received.

[The results of an ultrasonic study of the thyroid in patients with nodular goiter who were irradiated as a result of the accident at the Chernobyl Atomic Electric Power Station]. / Rezul'taty ul'trazvukovoho doslidzhennia shchytovydnoï zalozy u khvorykh na vuzlovyi zob, oprominenykh vnaslidok avariï na ChAES.

We studied the main values of ultrasonic scanning of patients with thyroid nodes depending on the dose, conditions of irradiation and sex. A total of 281 patients who had received a dose of irradiation of 0.01 to 2.0 Gr were evaluated; of these, 82 took part in the elimination of the effects of the Chernobyl accident (EEA) after evacuation, and 190 subjects were evacuees from the ChNPP 30-km zone, their age ranging between 20 to 68 years. In 43.6% of those having taken part in EEA, thyroid nodes did not exceed 1 cm across, in 44% node diameter was in the range 1 to 2 cm, in 12.4% it exceeded 2 cm. A screening examination revealed volume formations up to 1 cm in 79.5% of the evacuees, 1 to 2 cm across (9.4%), and in 13.02% node diameter exceeded 2 cm. In a major proportion of the examined patients the nodes were hypoechogenous. Distribution of echogenicity of nodes in male subjects does not depend on the dose and period of irradiation. A suggestion is made to the effect that ChNPP accident factors are not involved in the development of nodular forms of goiter in the immediate 7 years following irradiation.

[Thyroid diseases and the dynamics of their development in those convalescing from acute radiation sickness]. / Zakhvoriuvannia shchytovydnoï zalozy ta dynamika ïkh rozvytku u rekonvalestsentiv hostroï promenevoï khvoroby.

Patternture was studied together with the time course of development of thyroid disorders in 81 patients who had survived acute radiation sickness (ARS) in 1986, 88 irradiated individuals with unconfirmed ARS diagnosis, and 365 control, by results of clinical and laboratory examination carried out in 1989-1993. Increase in the incidence of functional disorders, especially that of hypothyrosis in the irradiated subjects (4.97% to 6.82%) can be regarded as realization of thyroidal non-stochastic effects in the immediate postaccident period.