RESUMO
We present a newborn diagnosed with posterior amorphous corneal dystrophy (PACD). PACD is a rare disorder with partial or complete posterior lamellar corneal opacification. Genetic screening showed a deletion of chromosome 12q21.33-q22 containing the identified four small leucine-rich proteoglycans (SLRP's) associated with this particular dystrophy. Neither parents were carrier of the deletion. To our knowledge, this is the first report of a de novo mutation causing PACD.
Assuntos
Deleção Cromossômica , Cromossomos Humanos Par 12 , Distrofias Hereditárias da Córnea/genética , Proteoglicanos Pequenos Ricos em Leucina/genética , Adulto , Hibridização Genômica Comparativa , Distrofias Hereditárias da Córnea/diagnóstico , Feminino , Humanos , Lactente , Análise de Sequência com Séries de OligonucleotídeosRESUMO
We report a case of infectious orbital cellulitis complicating a frontal sinusitis in a seventy-three-year-old patient. The onset of this orbital complication was sudden. A clinical examination and an orbital CT-scan allowed an early diagnosis. Despite an appropriate surgical and medical treatment, the patient retains an altered visual function. We consider the clinical causes and consequences of orbital cellulitis as well as their surgical indications.
Assuntos
Celulite Orbitária/diagnóstico , Idoso , Serviço Hospitalar de Emergência , Exoftalmia/etiologia , Sinusite Frontal/complicações , Humanos , Masculino , Celulite Orbitária/complicações , Tomografia Computadorizada por Raios XRESUMO
Using microwave currents, we excite resonances of geometrically confined pinned domain walls, detecting the resonance by the rectification of the microwave current. By applying magnetic fields, the resonance frequency of the domain wall oscillator can be tuned over a wide range. Increasing the power leads to a redshift due to the nonlinearity of the system. From this frequency shift, we directly deduce the quantitative shape of the potential, so that a complete characterization of the pinning potential is obtained.
RESUMO
Since April 28th, a new topical retinoid is available in Belgium: tazarotene (Zorac) gel (Pierre Fabre). It exists at two concentrations: 0.05% or 0.1%. It is the first receptor-selective topical retinoid. It is indicated in the treatment of plaque-type psoriasis. In the USA, tazarotene is also licensed for use in the treatment of acne and several studies show its efficacy for the treatment of other skin diseases like photodamage and ichthyoses.
