[Advances of studies on the biophysical and biochemical properties of meridians].

The essence of meridian-collateral system is one of the momentous theoretical topics of the life science. In recent years, many authors have been trying to elucidate various kinds of meridian phenomenon from different points of view including physics, chemistry, biology, traditional Chinese medicine, modern science and so on. The physical detection results intuitively indicated biophysics specificities of meridians, including electricity, heat, sound, light, magnesium, the migration of the injected isotope along the running route of meridians and so on. Results of the studies on chemical materials (ion, PO2, neurotransmitters) within the tissues along the meridian and those of cell junction communications showed that some chemical substances have a close relation with the meridian activities. This review summarizes recent research results on meridian and acupoints from biophysics and biochemistry in order to have a comprehensive understanding in this field.

[Effect of Bushen Yiqi Hexue recipe on endometrial P21 expression of embryo implantation dysfunctional mice].

OBJECTIVE: To observe the effect of Bushen Yiqi Hexue recipe on endometrial P21 and PCNA expression of embryo implantation dysfunctional mice. METHOD: The expression of P21 protein was analyzed by means of immunoblot and immunohistochemical method. The expression of PCNA protein was analyzed by means of immunohistochemical method. RESULT: The expression and disappearance of P21 and PCNA protein in endometrium of embryo implantation dysfunctional mice lagged behind in a temporal and cell specific manner. Bushenyiqihexue recipe could improve the expression of P21 and PCNA protein in a temporal and cell specific manner, and then improve the decidual reaction of endometrium of embryo implantation dysfunctional mice. CONCLUSION: Improving the expression of P21 and PCNA protein in endometrium and eventually regulating endometrium decidual reaction is one of the mechanisms of improved embryo implantaion by Bushen Yiqi Hexue recipe.