RESUMO
The purpose of this study is to discriminate mild Alzheimer's disease (AD) patients from the normal aging. The EEG coherence was applied to analyze the data from auditory oddball paradigm to discriminate the differences of corticocortical connections between mild AD patients and healthy subjects. The results showed that the lower values of coherence were performed in mild AD patients than in the normal aging subjects, especially in theta band. The implications and suggestions are shown in this study.
RESUMO
The aim of this paper is applying the bispectral analysis on widespread diffuse cross-frequency interactive effects. The event-related potentials (ERPs) research method was used in this study and it could collect the widespread diffuse cross-frequency from mild cognitive impairment (MCI) patients' brain wave. In this study, the brain wave data were collected from 12 MCI subjects, 12 healthy elderly, and 12 healthy young. The findings showed that the decreased interhemispheric coherence of 8.8 Hz for MCI compared with healthy elderly in the central-parietal cortex to respective surrounding sites and each MCI subject showed significantly widespread diffuse pattern of cross-frequency interactions in comparison with the healthy controls in the left central-parietal and right frontal. This study provides some explanation and suggestions for these findings.
