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1.
Clin. transl. oncol. (Print) ; 23(3): 425-433, mar. 2021. ilus
Artigo em Inglês | IBECS | ID: ibc-220878

RESUMO

Cancer is a serious public health problem in the world and the prevention and control of cancer has become one of the health strategies of governments around the world. According to the data of the International Agency for Research on Cancer (IARC), about 8 million people die of cancer every year in the world. With the continuous progress of medical technology, there are many methods to treat cancer at present. However, many treatment methods have achieved different therapeutic effects, some of them have obvious toxic and side effects. Therefore, it is necessary to study simpler and more effective new therapies for alleviating pain and prolonging lifetime of patients. In this view, we focus on the application progress of CRISPR system in some major cancers and its potential in cancer treatments (AU)


Assuntos
Humanos , Masculino , Feminino , Proteína 9 Associada à CRISPR/uso terapêutico , Sistemas CRISPR-Cas , Edição de Genes/métodos , Terapia Genética , Neoplasias/genética , Neoplasias/terapia , Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas , Endodesoxirribonucleases , Técnicas de Inativação de Genes , Antineoplásicos Imunológicos , Mutação
2.
Clin Transl Oncol ; 23(3): 425-433, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32671729

RESUMO

Cancer is a serious public health problem in the world and the prevention and control of cancer has become one of the health strategies of governments around the world. According to the data of the International Agency for Research on Cancer (IARC), about 8 million people die of cancer every year in the world. With the continuous progress of medical technology, there are many methods to treat cancer at present. However, many treatment methods have achieved different therapeutic effects, some of them have obvious toxic and side effects. Therefore, it is necessary to study simpler and more effective new therapies for alleviating pain and prolonging lifetime of patients. In this view, we focus on the application progress of CRISPR system in some major cancers and its potential in cancer treatments.


Assuntos
Sistemas CRISPR-Cas , Edição de Genes/métodos , Neoplasias/genética , Neoplasias/terapia , Proteínas de Bactérias , Proteína 9 Associada à CRISPR , Proteínas Associadas a CRISPR , Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas , Neoplasias Colorretais/genética , Neoplasias Colorretais/terapia , Endodesoxirribonucleases , Feminino , Técnicas de Inativação de Genes , Terapia Genética , Humanos , Imunoterapia/métodos , Neoplasias Hepáticas/genética , Neoplasias Hepáticas/terapia , Neoplasias Pulmonares/genética , Neoplasias Pulmonares/terapia , Linfoma/genética , Linfoma/terapia , Masculino , Mutação , Neoplasias da Próstata/genética , Neoplasias da Próstata/terapia , Pesquisa , Neoplasias do Colo do Útero/genética , Neoplasias do Colo do Útero/terapia , Neoplasias do Colo do Útero/virologia
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