RESUMO
Body weight support (BWS) is becoming an increasingly tool popular in rehabilitation settings, but little is known about how weight support effects reflex activity. Lower extremity Hoffman (H) reflex and tendon reflex responses were used to assess motoneuron excitability as a function of static lower extremity weightbearing load in neurologically normal individuals. Factors that are known to affect reflex activity, such as body orientation, movement and task phase were kept constant. Twenty three subjects were studied under three static load conditions (50%, 75% and 100% weightbearing) using four different stimulus conditions (soleus H-reflex, soleus H-reflex with vibration, Achilles tendon reflex, quadriceps tendon reflex). Load had no effect on any of the reflexes studied; we hypothesize that under static conditions, lower extremity reflexes are not affected by superincumbent load.
Assuntos
Peso Corporal , Perna (Membro) , Neurônios Motores/fisiologia , Músculo Esquelético/fisiologia , Suporte de Carga , Tendão do Calcâneo/fisiologia , Adulto , Feminino , Reflexo H/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Valores de Referência , Reflexo de Estiramento/fisiologia , Coxa da Perna , VibraçãoRESUMO
The Forkhead gene (FKH) regulates morphogenesis in Drosophila. It is the prototype of a new family of transcriptional activators. We used the polymerase chain reaction (PCR) to analyze the expression pattern of this new transcriptional regulatory gene family in primitive hematopoeitic progenitors. Partially degenerate oligonucleotides to two conserved amino acid sequences of this family were used to prime a PCR amplification of cDNA synthesized from CD34+/HLA-DR- hematopoietic cells. Known and novel FKH genes were found to be expressed in these cells.
