[Bacterial liver abscess cured by nonsurgical treatment. Comments on 8 cases]. / Abcesul hepatic bacterian vindecat sub tratament nechirurgical. Consideratii asupra opt cazuri.

Eight cases (3 children aged 7-15 years and 5 adults aged 16-46 years) of hepatic abscess in whom a cure was obtained by medical therapy are presented. The abscess occurred during septicemia (2 cases), cutaneous staphylococcosis (2 cases) and pyocholecystitis (1 case). In 3 patients the abscess remained cryptogenic. The clinical diagnosis was confirmed by scintigraphy, ultrasonography and in one case by radiography with contrast substance in the abscess. The microorganisms, isolated in 3 patients from the abscess and in one patient from hemoculture, were S. aureus (3 cases) and gram negative bacilli (1 case). The systemic antibiotic therapy consisted in the administration of gentamicin and oxacillin or rifampicin in 4 cases and gentamicin and chloramphenicol or ampicillin and metronidazole in other 4 cases for an average interval of 39 days. The associated local therapy (3 cases) consisted in one or more punctures, followed by the injection of gentamicin.

[Convulsive syndrome in infantile shigellosis]. / Sindromul convulsiv în shigeloza sugarului. Frecventa si consideratii patogenice.

Infantile shigellosis determines convulsions almost 5 times more frequently than the diarrheas of other etiology, the hyperpyrexy favouring significantly its release, on the background of a genetic disturbance and cerebral hypoxic mechanism.

[The hand, foot and mouth disease. Clinical premiere in our country]. / Boala gura-mîna-picior, premiera clinica în tara noastra.

In May 1981 the hand, foot and mouth disease was diagnosed for the first time in Ramaia in a 4 year old child. The onset of the disease was characterized by moderate fever, coryza and spontaneous endobuccal pains followed at a short interval of time by the simultaneous of a papulo-vesicular eruption on hands and feet. The eruption was prevalent on the hands and feet fingers as well as on the palmar and plantar regions. Isolated aphthous lesions were seen on the vestibular mucosa. Morphologically, the intraepidermic site of the lesion with an advanced acantholytic process in the vesicular area was noticed. In the superficial and deep tissue perivascular infiltrate with mononucleares were present.

["Minor" salmonelloses on the offensive; clinico-epidemiological aspects of Salmonella agona infections]. / Salmonelozele "minore" in ofensiva, aspecte clinicoepidemiologice ale infectiei cu Salmonella agona.

The incidence of "minor" salmonelloses, (one of the main infantile enteritis), has increased of late, the principal agent in 1977 and 1978 being Salmonella agona. The present paper is a clinico-epidemiological study of the characteristics of a recent episode comprising 46 cases due to Salmonella agona. Most of the cases treated in hospital had a prevalently enterocolitic aspect, without extraenteral complications, but with a reserved prognosis (10% mortality rate in the authors' experience) when associated with other diseases (bronchopneumonia, otitis, otoantritis) or when the child has a deficient constitution (congenital or acquired). It is difficult to get rid of the germ, of particular importance especially when the children return to children's institutions, by means of an etiotropic therapy, which in many cases may even delay elimination of the salmonellas. In Salmonella infections the carrier excretory state is intermittent rather than permanent. Salmonellosis caused by the agona serotype may be listed, as most of the so-called "minor" cases, in the "central" group according to the classification propossed by Newell and adopted by the World Health Organization in 1959.

[Effectiveness of repeated antibiotic or chemotherapeutic treatments on Shigella carrier states]. / Consideratii privind eficienta repetarii tratamentului cu antibiotice sau chimioterapice asupra portajului de shigella

A group of 39 former dysentery patients, who continued to excrete Shigella bacteria after a first cure of antibiotics when full clinical recovery was obtained, were treated differentially under bacteriological control. The carrier state was still extent in 7% of the cases after three antibiotic or chemotherapeutical cures. No direct relation was found between the sensitivity of Shigella to chemotherapeutics and the level of the carrier state. Although treated already in the acute stage with adequate antibiotics, resistance to a second therapeutical attempt was recorded in a proportion of 33%. It is considered useless to repeat the antibiotic or chemotherapeutical cures in the treatment of convalescent carriers because of the low efficiency and the biological and economical disadvantages.