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1.
Curr Top Med Chem ; 15(16): 1614-21, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25877088

RESUMO

At present, the use of dental implants is a very common practice as tooth loss is a frequent problem and can occur as a result of disease or trauma. An implant is usually made of biocompatible materials that do not cause rejection reactions and allow the implant union with the respective bone. To achieve this goal, the implant surface may have different structures and coatings, generally used to increase the adherence of the implant to the bone and to decrease the risk of the periimplantar inflammatory reactions. This review gives some insights of the metal based materials used for dental implants, their limits, improvement strategies as well as the pathophysiology, diagnosis, treatment and prevention of periimplantary diseases.


Assuntos
Materiais Biocompatíveis/química , Ligas Dentárias/química , Implantes Dentários , Peri-Implantite/etiologia , Materiais Biocompatíveis/efeitos adversos , Ligas Dentárias/efeitos adversos , Implantes Dentários/efeitos adversos , Humanos , Peri-Implantite/diagnóstico , Peri-Implantite/prevenção & controle
2.
Curr Top Med Chem ; 15(16): 1577-82, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25877091

RESUMO

The spectacular progress of research in the nanotechnology field led to the achievement of important knowledge of materials at the atomic and molecular scale and the extent of the use of nanoparticles in the design of medical products, ecological processes, cosmetics and other biotechnological applications. One of the current focuses of the medical applications of nanotechnology is the development of new strategies to inhibit the activity of different microorganisms. The purpose of this review was to present the antimicrobial activity of metal cations in micro- and nanoparticulate forms and the dependence of this biological activity on shape, size and physico-chemical conditions.


Assuntos
Anti-Infecciosos/química , Nanopartículas Metálicas/química , Metais Pesados/química , Nanotecnologia , Anti-Infecciosos/farmacologia , Bactérias Gram-Negativas/efeitos dos fármacos , Bactérias Gram-Positivas/efeitos dos fármacos , Metais Pesados/farmacologia , Tamanho da Partícula
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