1.
Korean Journal of Dermatology
; : 592-595, 2002.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-10676
RESUMO
We report a case of multiple Bowen's disease in a 36-year-old female patient who had multiple erythematous, scaly patches and plaques distributed diffusely on her trunk, upper and lower extremities. Histopathologic studies showed hyperkeratosis, parakeratosis, acanthosis, and thickening of the rete ridges in the epidermis. The cellular architecture is disorganized, and individually keratinizing cells and atypical cells were seen at all levels of the epidermis. The skin lesions were improved with treatment with oral isotretinoin, 0.5mg/kg per day in combination with interferon alpha-2a administrated subcutaneously at 3 million units once a week.