1.
Gut
; 67(10): 1751-1752, 2018 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28765475
Assuntos
Pólipos do Colo , Instabilidade de Microssatélites , Adenoma , Colonoscopia , Neoplasias Colorretais , Humanos
2.
Gastrointest Endosc Clin N Am
; 25(2): 169-82, 2015 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25839680
RESUMO
Colorectal cancer (CRC) is a heterogeneous disease and each CRC possesses a unique molecular tumor profile. The main pathways of oncogenesis are the chromosomal instability, microsatellite instability and serrated neoplasia pathway. Sessile serrated adenomas/polyps (SSA/Ps) may be the precursor lesions of CRC arising via the serrated neoplasia pathway. This has led to a paradigm shift because all SSA/Ps should be detected and resected during colonoscopy. The ability to accurately detect and resect only those polyps with a malignant potential could result in safer and cost-effective practice. Optimization of the endoscopic classification systems is however needed to implement targeted prevention methods.