[Analysis of effects of pharmacotherapy on certain parameters of clinical laboratory diagnostics].

AIM: To study effects of pharmaceutical products on the results of clinical and laboratory diagnostics. MATERIALS AND METHODS: The list of vitally important pharmaceuticals, clinico-pharmacological articles of the National registry of medicinal products, formulary articles from the Federal guidelines on the use of pharmaceutical products. Formulary system, instructions for use of individual pharmaceutical products. Systemic and information-based approaches, logical and comparative analysis were used throughout the study. RESULTS: Results of analysis enabled the authors to draw up separate lists of pharmaceuticals based on their influence on parameters of clinical laboratory diagnostics, such as the list of pharmaceuticals exerting marked effect on diagnostic characteristics (blood properties, primary and coagulative hemostasis, serum enzymes), the list of pharmaceuticals exerting marked effect on systematized laboratory characteristics; the list of pharmaceuticals exerting no effect on clinical and laboratory diagnostics; the list of pharmaceuticals whose effect on diagnostic characteristics awaits clarification. CONCLUSION: The results of the study can be used for the development of recommendations on pharmaceutical counseling and rational choice of pharmaceutical products being prescribed to concrete patients.

[Organization of drug assistance for the elderly].

The basic directions of optimization of drug help to senior citizens from the standpoint of rational use of medicines, taking into account the features of pharmacotherapy in these patients due to age-physiological processes in the body, polymorbidity, reduction of adaptation to the toxic effects of drugs, and the growing incidence of adverse side effects of drugs. The necessity to take into account these characteristics in the clinical trials of drugs, development of guidelines for their use, development standards or medical care, prescription drugs and establish a regime of receiving from therapists and professional counseling pharmacists by elderly patients when they contact the pharmacy organization is shown. The basic directions of organizational and pharmaceutical approaches for the rational use of drugs are discussed, the results of the analysis of information in the instructions for use are shown.