[Salicylate-induced modification of plant proteomes (review)].

Here we present a brief review of the reports concerning proteome modifications under the influence of salicylic acid, which is one of the major mediators of both local and systemic immunity. We describe also the results of our own studies of the salicylate-induced changes in proteomes of pea leaves and roots. Fifteen salicylate-inducible proteins, which were previously unknown, have been identified. Unlike the roots, leaves accumulated some chloroplast proteins and enzymes capable of degrading the pathogen cell walls. In the roots, salicylic acid increased the content of enzymes, improving the resistance of plant cells themselves, and promoted the disappearance of reductase of oxophytodienic acid. The latter could lead to inhibition of jasmonic acid synthesis and stimulation of local immunity. High (apoptotic) concentration of salicylic acid intensified synthesis of root proteins involved in the formation of heteroprotein complexes, which play an important role in the functioning of the signaling system, DNA synthesis and repair, and protein synthesis, refolding, and proteolysis.

[Immunological status and its changes in children during surgery on anterior eye segment]. / Immunologicheskii status i ego izmeneniia u detei pri provedenii operatsii na perednem otrezke glaznogo iabloka.

Nonspecific and specific immunity values were studied in 70 children before and in various periods after 74 operations on the anterior segment of the eyeball. In children with persistent autosensitization to ocular tissue autoantigens (alpha-crystalline and S-antigen) postoperative uveitis presented as an immunocomplex disease with signs of exhaustion of the functional potential of the phagocytosis and complement systems. In children without autosensitization uveitis was associated with immunity activation. Phagocytosis system and cooperation of lymphocyte subpopulations, including normal killers (CD16+), play an important role in prevention of sensitization to ocular tissue autoantigens. Therefore, complex immunological examinations of children before surgery and regular check-ups after it will help differentiate immunodeficiency from compensatory immunosuppression preventing autoimmune disease, which is important in prescription of immunostimulating therapy.