[Improved method of purification of L-lysine-alpha-oxidase from the fungus Trichoderma sp]. / Usovershenstvovannaia skhema ochistki L-lizin-alpha-oksidazy griba Trichoderma sp.

Relatively rapid procedure was developed for isolation and purification of the antitumor enzyme L-lysine alpha-oxidase. The procedure involved three steps instead of six or four steps described previously, with a yield of 64.4%. The homogenous preparation was obtained as shown by gel electrophoresis and ultracentrifugation. The antitumor activity of the enzyme both in vivo and in vitro is under investigation.

[Various physico-chemical properties of L-lysine-alpha-oxidase from Trichoderma sp]. / Nekotorye fiziko-khimicheskie svoistva L-lizin-alpha-oksidazy iz Trichoderma sp.

L-lysine-alpha-oxidase, isolated from a strain of Trichoderma sp. exhibited enzymological properties suitable for a chemotherapeutic drug used in experimental oncology.