1.
Ontogenez
; 8(1): 62-7, 1977.
Artigo
em Russo
| MEDLINE
| ID: mdl-882244
RESUMO
The effect of colchicine on morphogenesis of the regenerating nuclear fragments of Acetabularia mediterranea has been studied. Colchicine was shown to inhibit the formation of caps. The algae are most sensitive to colchicine at the early stages of regeneration. The breakdown of microtubules in the perinuclear cytoplasm of regenerating algae under the effect of colchicine was found under the electron microscopy. The breakdown of microtubules in this zone appears not to disturb the transport of morphogenetical substances in the apical cell part. Colchicine inhibits the morphogenesis, apparently, at the expense of protein inactivation in the zone of growth.
Assuntos
Acetabularia/efeitos dos fármacos , Clorófitas/efeitos dos fármacos , Colchicina/farmacologia , Acetabularia/crescimento & desenvolvimento , Acetabularia/ultraestrutura , Relação Dose-Resposta a Droga , Microscopia Eletrônica , Microtúbulos/efeitos dos fármacos , Regeneração/efeitos dos fármacos
2.
Dokl Akad Nauk SSSR
; 226(3): 725-8, 1976 Jan 21.
Artigo
em Russo
| MEDLINE
| ID: mdl-1253683