[Intensive therapy of DIC-syndrome in patients with acute renal insufficiency caused by long-term crush syndrome]. / Intensivnaia terapiia DVS-sindroma u bol'nykh s ostroi pochechnoi nedostatoch-nost'iu, obuslovlennoi sindromom dlitel'nogo sdavleniia.

Impairment of parenchymatous organs, primarily kidneys, responsible for their dysfunction in crush syndrome results in many respects from disseminated intravascular coagulation (DIC). It is also associated with hemorrhagic complications. It is demonstrated that treatment modalities aimed at arrest of DIC syndrome (plasmapheresis, heparin, dysaggregation drugs, transfusions of large amounts of fresh frozen plasma) stopped bleeding and septic shock in 12 patients with crush syndrome following the earthquake in Armenia (1988).

[Relation between arterial hypertension and disorder of erythrocyte deformability in patients with chronic renal failure]. / O sviazi mezhdu arterial'noi gipertoniei i narusheniem deformiruemosti éritrotsitov u bol'nykh s khronicheskoi pochechnoi nedostatochnost'iu.

A total of 29 patients with chronic renal insufficiency (CRI) were investigated. Noticeable disorder of erythrocytic deformability (ED) was detected in half of them. The expression of arterial hypertension showed correlation with a degree of ED disorder. A possibility of the main role of ED disorder in the development and progression of arterial hypertension was discussed. ED disorder was found to correlate with a degree of expression of laboratory signs of the DIC-syndrome and was practically unassociated with the blood level of creatinine.

[Correction of blood rheological disorders in patients with chronic kidney failure using heparin and antiaggregants]. / Korrektsiia gemoreologicheskikh narushenii u bol'nykh s khronicheskoi pochechnoi nedostatochnost'iu geparinom i dezagregantami.

The state of microcirculation and blood rheology was studied in 32 patients with chronic renal insufficiency. Improved microcirculation and the reduction of clinico-laboratory indices of the DIC-syndrome were noted against a background of heparin and antiaggregant therapy in patients on programmed hemodialysis as well as in patients receiving systemic conservative therapy. In both groups of patients blood pressure decreased in parallel with a decrease in the level of creatinine and urea; a tendency toward improved renal function was noted.

[Problems in the treatment of the anemic syndrome in patients with chronic kidney failure]. / Nekotorye voprosy lecheniia anemicheskogo sindroma u bol'nykh s khronicheskoi pochechnoi nedostatochnost'iu.

The paper is concerned with the efficacy of plasmapheresis with regard to red blood values in CRF patients on hemodialysis therapy. The probable mechanisms of this positive effect are discussed. Correlation between a degree of expression of the DIC-syndrome and anemia severity is demonstrated. An original method for reducing loss of blood in the dialyzer has been proposed.