[Structural analysis of the information value of lung ventilation parameters for assessment of bronchodilation response in patients with bronchial asthma].

The goal of this work was to perform structural analysis of the information value of lung ventilation parameters for assessment of bronchodilation response in patients with bronchial asthma. The information value of lung ventilation parameters is considered as a function of the initial level of ventilation disorders and the method of calculation of bronchodilation response. Structural analysis revealed that different lung ventilation parameters have different information value for assessment of bronchodilation response in patients with bronchial asthma. The effect of the method of calculation and the initial severity of ventilation disorders on the information value of lung ventilation parameters is also rather complex. Parameters with maximal information value for analysis of the results of broncholytic tests in patients with bronchial asthma are determined. These parameters have high information value independently of the method of calculation.

[Analysis of diagnostic efficiency of lung ventilation parameters in patients with bronchial asthma].

The goal of this work was to perform probabilistic assessment of the diagnostic efficiency of lung ventilation parameters in patients with bronchial asthma. The efficiency of the suggested method was compared with that of the widely used technique of contrast of means. Study was performed in 365 patients with bronchial asthma and 216 apparently healthy subjects. Structural analysis of the diagnostic efficiency of lung ventilation parameters was performed on the basis of pooled and separate estimates. The results of the study made it possible to classify the lung ventilation parameters according to the degree of their diagnostic validity.

[Structural analysis of diagnostic efficiency of bodyplethysmography indexes in patients with bronchial asthma].

In the paper the probabilistic assessment of diagnostic efficiency of bodyplethysmography indexes in patients with bronchial asthma instead of the prevailing method of comparison of mean-value is carried out. It is shown, that the estimation of diagnostic efficiency of body-plethysmography indexes by probabilistic methods in patients with bronchial asthma has advantages in comparison with a traditional estimation of mean-value as allows to determine the information density of each size from a position of probability and to improve functional diagnostics of this disease.