RESUMO
INTRODUCTION: Anti-Hu and anti-Yo are the most well-known anti-neuronal antibodies. The anti-Ri antibodies, which are less common, are generally found in subjects with opsoclonus-myoclonus, often associated with breast cancer. CASE REPORT: A 54-year-old woman presented anti-Ri antibodies associated with a paraneoplastic syndrome and unusual symptoms of ophthalmoplegia, blepharospasm, palilalia and ataxia. Adenocarcinoma of the breast was also found. After chemotherapy, radiotherapy, and several immunoglobulin infusions, the patient did not improve ten months after tumor surgery. CONCLUSION: Anti-Ri antibodies associated with paraneoplastic syndrome can be observed in patients who develop a rapidly progressive brainstem tumor. Breast or lung cancer and conduct to search a breast or pulmonary cancer.
Assuntos
Autoanticorpos/imunologia , Blefarospasmo/etiologia , Oftalmoplegia/etiologia , Síndromes Paraneoplásicas do Sistema Nervoso/complicações , Distúrbios da Fala/etiologia , Adenocarcinoma/complicações , Adenocarcinoma/tratamento farmacológico , Adenocarcinoma/terapia , Antineoplásicos/uso terapêutico , Blefarospasmo/imunologia , Neoplasias da Mama/complicações , Neoplasias da Mama/tratamento farmacológico , Neoplasias da Mama/terapia , Feminino , Humanos , Imunização Passiva , Pessoa de Meia-Idade , Oftalmoplegia/imunologia , Síndromes Paraneoplásicas do Sistema Nervoso/imunologiaAssuntos
Diplopia/etiologia , Policondrite Recidivante/complicações , Idoso , Humanos , Masculino , Recidiva , Uveíte/etiologiaRESUMO
We report one case of acute cervical spinal cord infarction characterized by motor impairment of the upper limbs with respect of the lower limbs. It occurs infrequently. The purpose of this paper is to discuss the clinical, neurophysiological and magnetic resonance imaging findings, and to review the presumed mechanisms of spinal cord infarction.