[Role of Yq11-chromosome microdeletion in the development of nonobstructive infertility in men]. / Rol' mikrodeletsii khromosomnoï dilianky Yq11 v rozvytku neobstruktyvnykh form cholovichoho bezpliddia.

Recent studies have shown that a significant proportion of men with severe infertility had microdeletions of the Y-chromosome. It has thus become important to screen men with a high risk of the Y-chromosome microdeletions, as this will determine if counseling is needed prior to starting infertility treatment. The current state of knowledge about the nature of genes responsible for spermatogenesis and significance of microdeletions of the Y-chromosome for male infertility are analyzed in the review.