[The role of adrenergic stimulation of the arteries in their developing rhythmic contractions in arterial normo- and hypertension in rats]. / Rol' adrenergicheskoi stimuliatsii arterii v formirovanii ikh ritmicheskikh sokrashchenii pri arterial'noi normo- i gipertenzii u krys.

In anaesthetised Wistar and SHR rats, rhythmic contractile responses of mesenteric arteries to noradrenaline as well as sympathetic nerve stimulation, were studied. Under equal experimental conditions, different parameters of vasomotion in normo- and hypertensive rats were revealed.

[The effect of polarization of the vascular wall on the ion transport and contractile activity of the rat tail artery]. / Vliianie poliarizatsii sosudistoi stenki na transport ionov i sokratitel'nuiu aktivnost' khvostovoi arterii krys.

The effects of the blood velocity upon the responsiveness of blood vessels seem to be based on the processes inducing a deforming of the diffuse part of a double electrical layer at the border between the blood and vascular wall of the rat tail artery. Salts of polyvalent metals were found to diminish the negativity of the transmural potential and to diminish the contractile activity and the tone of the blood vessels. Heparin exerted an opposite effect.

[The effect of glucocorticoid hormones on the blood pressure and contractile activity of the mesenteric arteries in rats]. / Vliianie gliukokortikoidnykh gormonov na krovianoe davlenie i sokratitel'nuiu aktivnost' arterii bryzheiki krys.

Methylprednisolone (MP) induced first a decrease and then an increase of the blood pressure in Wistar rats. The hypertensive effect stabilised after three administrations. The contractile response amplitude in electric stimulation of the vascular-motor nerves first increased and then sharply dropped. The glycocorticoids were concluded to reduce the contractile properties of vessels simultaneously increasing the blood pressure.

[The significance of rhythmic contractile activity of the arteries for the regulation of the rate of blood flow]. / O znachenii ritmicheskoi sokratitel'noi aktivnosti arterii dlia reguliatsii skorosti krovotoka.

The effect of rhythmic contractile activity of the rat mesenteric arteries upon the blood flow velocity, was studied. The vasomotion was induced both by a direct stimulation of vascular motor nerves and a nociceptive stimulation. The wave of the vasomotion was shown to spread towards the periphery of the arterial bed irrespective of the way of influencing. The mathematical model of the vessel as a peristaltic pump working against the background of a constant shifting of the pressure with the contraction wave's parameters measured during the experiments, revealed that the blood flow velocity equally depended on the amplitude and the velocity of spreading of the rhythmic contractions. The experiments suggest involvement of the sympathetic nervous system in the control of the vasomotion's parameters and, consequently, of the blood flow velocity in the vessels during latters' rhythmic contractile activity.

[Electrochemical phenomena in autoregulatory reactions of the blood vessels]. / Rol'élektrokhimicheskikh iavlenii v autoreguliartornykh reaktsiiakh krovenosnykh sosudov.

Some physiological mechanisms being in the basis of autoregulatory reactions of blood vessels have been studied. It has been found that the rise in the difference of the potentials of electrochemical origin between inner and exterior vessel surfaces during blood movement facilitates to increase the vessel myogenic reaction at the intravascular pressure rise, to intensify spontaneous bioelectrical activity of smooth muscle cells and hydration of a vascular wall. These phenomena are reproduced by the application to a vessel a constant potential commensurable with one rising during blood movement.

[Effect of blood movement on the reactivity of blood vessels]. / Vliianie dvizheniia krovi na reaktivnost' kovenosnykh sosudov.

The influence of electrokinetic phenomena arising from blood movement on reactivity of blood vessels has been studied. The potential difference, as it has been established, occurs during blood movement along a vessel between its internal and external surfaces, being dependent upon the rate of blood movement, and the internal one becomes negatively charged. Blood movement facilitates penetration of molecules of dye with a positive charge into a vessel wall. The contractile response of a vessel to the stimulation of vasomotor nerves gradually increases with a start of blood movement and decreases after a blood stop. Artificially applied potential difference between the internal and external vessel surfaces results in the changes of contractile response and vessel tone. The role of electrokinetic phenomena in regulation of contractile ability and vessel tone is discussed.