Stimulation of penetrating corneal wound healing by exogenous fibronectin.

The paper describes the effect of exogenous fibronectin administered by instillation on the repair of the rabbit cornea after experimental mechanical injury. The effect was monitored by light microscopy and radioautography. Fibronectin had a beneficial effect on regenerating corneal epithelium, endothelium and keratocytes through a stimulatory effect on cell migration, proliferation and differentiation.

[Effects of fibronectin instillation on reparative regeneration of the corneal tissue (an experimental study)]. / Vliianie instilliatsii fibronektina na reparativnuiu regeneratsiiu rogovichnoi tkani (éksperimental'noe issledovanie).

Comprehensive morphologic studies (including light microscopy, morphometry, autoradiography) of experimental rabbits have revealed a stimulating effect of fibronectin instillations on healing of central penetrating wounds of the cornea. A polypotent mechanism of the stimulating effect of fibronectin instillations during all the stages of the reparative process in the corneal tissue was proved.

[A new enriched balanced irrigation solution for intraocular surgery (experimental study)]. / Novyi obogashchennyi sbalansirovannyi irrigatsionnyi rastvor dlia vnutriglaznoi khirurgii (éksperimental'noe issledovanie).

Experimental trials of a new intraocular irrigation solution, one of the enriched balanced salines, were carried out. A comprehensive morphologic study has revealed the protector characteristics of lactosol plus (lactosol + taurin) used in the management of irrigation injury to the posterior epithelium of the cornea in the course of experimental intrachamber perfusion. The protective properties of lactosol + taurin, a new enriched balanced saline, are explained by the similarity of its chemical composition to that of the intraocular fluid and by the presence of a stable polyfunctional bioprotector, taurin amino acid.