[Routine antibiotic therapy in cesarean section?]. / Antibioticoterapia rutinaria en cesárea?

From August 1988 to January 1989 at the Obstetrical service of the "Nuevo Hospital Civil de Guadalajara" we studied 150 patients with cesarean section without risk of infection. Three groups of 50 patients each were formed. Group A: had no antibiotics; Group B: antibiotic prophylaxis with penicillin, and Group C: ampicillin plus gentamicin for 7 to 10 days. The results were similar in the three groups as to patient's age, obstetrical history, cesarean section's indication, type of amniotic fluid, sex-weight and Apgar of the newborn, curve of body temperature, white blood cells and bands intrahospital. Only one patient had infection of the wound of the group A and other patient of the group C; from group B had a subaponeurotic hematoma (p less than 0.7). We concluded that the antibiotics must not use routinely, only when the patients have an infection risk.

[Eclampsia management at the Civil Hospital Medical Complex of Guadalajara]. / Manejo de la eclampsia en el Complejo Médico Hospital Civil de Guadalajara.

Prospectively from 1986 to 1988 we studied at the "Complejo Médico Hospital Civil de Guadalajara" 17 eclamptic patients treated with diazoxide besides magnesium sulfate, diazepam and dexamethasone. The average age was 25.4 years, the average gestational age was 33.5 weeks and the average dose of diazoxide was 210 mgs. In the 88.2% of the patients the general anesthesia was used. The average Apgar at minute was 6.6 and 8.8 at five minutes. The newborns average weight was 2,135 g. We had one maternal death (5.8%) and two perinatals demise (11.8%). The more frequent maternal complications were the blindness and oliguria postdelivery and the average maternal hospitalization was 5.7 days.

[Effect of naloxone on somatosensory evoked potentials in congenital insensitivity to pain]. / Efecto de naloxona sobre los potenciales evocados somatosensoriales en la insensibilidad congénita al dolor.

The somatosensory evoked potentials were recorded (SEP) in a child 11 years old with congenital insensitivity to pain. The records were made before and after naloxone administration (160 mg i.m.) and they were compared with the SEPs from normal children. The place where records were taken was the somatosensory area of the scalp and the site of the stimulation was the contralateral medial nerve of the wrist. The results show that naloxone provokes higher waves of the patient's SEP that before administration of naloxone. On the other hand lower SEPs were observed in the patient with congenital insensitivity to pain than in those from normal children. The results suggest that congenital insensitivity to pain could be related to abnormal activities of morphine-like substances of endogenous production.

Efecto de naloxona sobre los potenciales evocados somatosensoriales en la insensibilidad congenita al dolor. / Effect of naxolone on the somatosensory evoked potentials in congenital insensibility to pain

Se hizo registro de los potenciales evocados somatosensoriales(PES) en un nino de 11 anos con insensibilidad congenita al dolor antes y despues de la administracion de naloxona (160 mg.i.m.) y se compararon con los PES de ninos aparentemente sanos.Los resultados parecen indicar que la naloxona produce un aumento en la amplitud de los componentes de los PES registrados en el area somatosensorial del cuero cabelludo, contralateral al sitio de estimulacion en el nervio mediano a nivel de la muneca, por otra parte, hay una clara disminucion en la amplitud de los componentes de los PES registrados en el paciente con insensibilidad congenita al dolor con respecto a los obtenidos en un nino normal.Los resultados apoyan la suposicion de que los pacientes con insensibilidad congenita al dolor existe un aumento en las sustancias de produccion endogena parecidas a la morfina (endorfinas)