1.
Drug Des Discov
; 15(4): 269-75, 1998 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10546071
RESUMO
A series of pyridine-2-, pyrazine-2- and quinoline-2-carboxamidrazone derivatives was prepared in an automated fashion and tested against Mycobacterium fortuitum in a rapid screen. Seven pyridine-2-carboxamidrazone derivatives were investigated further and four were found to have inhibitory activity with compound 4af being the most active. The structure activity implications are discussed.