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1.
Membranes (Basel) ; 13(10)2023 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-37887982

RESUMO

Multifunctional membrane technology has gained tremendous attention in wastewater treatment, including oil/water separation and photocatalytic activity. In the present study, a multifunctional composite nanofiber membrane is capable of removing dyes and separating oil from wastewater, as well as having antibacterial activity. The composite nanofiber membrane is composed of cellulose acetate (CA) filled with zinc oxide nanoparticles (ZnO NPs) in a polymer matrix and dipped into a solution of titanium dioxide nanoparticles (TiO2 NPs). Membrane characterization was performed using transmission electron microscopy (TEM), field emission scanning electron microscopy (FESEM), and Fourier transform infrared (FTIR), and water contact angle (WCA) studies were utilized to evaluate the introduced membranes. Results showed that membranes have adequate wettability for the separation process and antibacterial activity, which is beneficial for water disinfection from living organisms. A remarkable result of the membranes' analysis was that methylene blue (MB) dye removal occurred through the photocatalysis process with an efficiency of ~20%. Additionally, it exhibits a high separation efficiency of 45% for removing oil from a mixture of oil-water and water flux of 20.7 L.m-2 h-1 after 1 h. The developed membranes have multifunctional properties and are expected to provide numerous merits for treating complex wastewater.

2.
Multidiscip Respir Med ; 18: 917, 2023 Jan 17.
Artigo em Inglês | MEDLINE | ID: mdl-37692055

RESUMO

Background: The International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC) 4C mortality score has been used before as a valuable tool for predicting mortality in COVID-19 patients. We aimed to address the utility of the 4C score in a well-defined Saudi population with COVID-19 admitted to a large tertiary referral hospital in Saudi Arabia. Methods: A retrospective study was conducted that included all adults COVID­19 patients admitted to the Armed Forces Hospital Southern Region (AFHSR), between January 2021 and September 2022. The receiver operating characteristic (ROC) curve depicted the diagnostic performance of the 4C Score for mortality prediction. Results: A total of 1,853 patients were enrolled. The ROC curve of the 4C score had an area under the curve of 0.73 (95% CI: 0.702-0.758), p<0.001. The sensitivity and specificity with scores >8 were 80% and 58%, respectively, the positive and negative predictive values were 28% and 93%, respectively. Three hundred and sixteen (17.1%), 638 (34.4%), 814 (43.9%), and 85 (4.6%) patients had low, intermediate, high, and very high values, respectively. There were significant differences between survivors and non-survivors with regard to all variables used in the calculation of the 4C score. Multivariable logistic regression analysis revealed that all components of the 4C score, except gender and O2 saturation, were independent significant predictors of mortality. Conclusions: Our data support previous international and Saudi studies that the 4C mortality score is a reliable tool with good sensitivity and specificity in the mortality prediction of COVID-19 patients. All components of the 4C score, except gender and O2 saturation, were independent significant predictors of mortality. Within the 4C score, odds ratios increased proportionately with an increase in the score value. Future multi-center prospective studies are warranted.

3.
Biomolecules ; 13(7)2023 07 11.
Artigo em Inglês | MEDLINE | ID: mdl-37509137

RESUMO

The biosynthesis of silver nanoparticles (Ag NPs) could play a significant role in the development of commercial antimicrobials. Herein, the biosynthesis of Ag NPs was studied using the edible mushroom Pleurotus floridanus, and following its formation, spectrophotometry was used to detect the best mushroom content, pH, temperature, and silver concentration. After that, the morphology was described via transmission electron microscopy (TEM), and nanoscale-size particles were found ranging from 11 to 13 nm. The best conditions of Ag content and pH were found at 1.0 mM and 11.0, respectively. In addition, the best mushroom extract concentration was found at 30 g/L. According to XRD analysis, the crystal structure of the formed amorphous Ag NPs is cubic with a space group of fm-3m and a space group number of 225. After that, the function groups at the surface of the prepared Ag NPs were studied via FTIR analysis, which indicated the presence of C=O, C-H, and O-H groups. These groups could indicate the presence of mushroom traces in the Ag NPs, which was confirmed via the amorphous characteristics of Ag NPs from the XRD analysis. The prepared Ag NPs have a high impact against different microorganisms, which could be attributed to the ability of Ag NPs to penetrate the cell bacterial wall.


Assuntos
Anti-Infecciosos , Nanopartículas Metálicas , Nanopartículas Metálicas/química , Antibacterianos/farmacologia , Antibacterianos/química , Prata/química , Seguimentos , Anti-Infecciosos/farmacologia , Espectroscopia de Infravermelho com Transformada de Fourier , Extratos Vegetais/química
4.
Multidiscip Respir Med ; 18(1): 915, 2023 Jan 17.
Artigo em Inglês | MEDLINE | ID: mdl-37265943

RESUMO

Background: In COVID-19 patients undetected co-infections may have severe clinical implications associated with prolonged hospitalization, ICU admission, and mortality. Therefore, we aimed to investigate the impact of viral coinfections on the outcomes of hospitalized patients with COVID-19 in a large tertiary Saudi Arabian Hospital. Methods: A total of 178 adult patients with confirmed SARS-CoV-2 who were hospitalized at the Armed Forces Hospital Southern Region (AFHSR), Saudi Arabia, from March 1st to June 30th 2022, were enrolled. Real-time PCR for the detection of viral co­infections was carried out. Cases (SARS-CoV-2 with viral coinfections) and control (SARS-CoV-2 mono-infection) groups were compared. Results: 12/178 (7%) of enrolled COVID-19 patients had viral coinfections. 82/178 (46%) of patients were males. 58% of patients had comorbidities. During the study period, 4/12 (33%) and 21/166 (13%) cases and control patients died, p=0.047, respectively. Duration of hospitalization was the only significant independent factor associated with SARS-CoV-2 coinfections, OR 1.140, 95% CI 1.020-1.274, p=0.021. Conclusions: The findings of this study from a large tertiary Saudi Arabian Center revealed a prevalence of 7% for SARS-CoV-2 viral coinfections. SARS-CoV-2 coinfected patients had a significantly prolonged duration of hospitalization and higher mortality than those with SARS-CoV-2 alone. Future studies are needed.

5.
Sci Rep ; 13(1): 3876, 2023 Mar 08.
Artigo em Inglês | MEDLINE | ID: mdl-36890178

RESUMO

The catalytic conversion of waste cooking oil (WCO) was carried out over a synthetic nano catalyst of cobalt aluminate (CoAl2O4) to produce biofuel range fractions. A precipitation method was used to create a nanoparticle catalyst, which was then examined using field-emission scanning electron microscopy, X-ray diffraction, energy dispersive X-ray, nitrogen adsorption measurements, high-resolution transmission electron Microscopy (HRTEM), infrared spectroscopy, while a gas chromatography-mass spectrometer (GC-MS) was used to analyze the chemical construction of the liquid biofuel. A range of experimental temperatures was looked at including 350, 375, 400, 425, and 450 °C; hydrogen pressure of 50, 2.5, and 5.0 MPa; and liquid hour space velocity (LHSV) of 1, 2.5, and 5 h-1. As temperature, pressure, and liquid hourly space velocity increased, the amount of bio-jet and biodiesel fractional products decreased, while liquid light fraction hydrocarbons increased. 93% optimum conversion of waste cooking oil over CoAl2O4 nano-particles was achieved at 400 °C, 50 bar, and 1 h-1 (LHSV) as 20% yield of bio-jet range,16% gasoline, and 53% biodiesel. According to the product analysis, catalytic hydrocracking of WCO resulted in fuels with chemical and physical characteristics that were on par with those required for fuels derived from petroleum. The study's findings demonstrated the nano cobalt aluminate catalyst's high performance in a catalytic cracking process, which resulted in a WCO to biofuel conversion ratio that was greater than 90%. In this study, we looked at cobalt aluminate nanoparticles as a less complex and expensive alternative to traditional zeolite catalysts for the catalytic cracking process used to produce biofuel and thus can be manufactured locally, which saves the cost of imports for us as a developing country.

6.
Biochem Biophys Res Commun ; 649: 118-124, 2023 03 15.
Artigo em Inglês | MEDLINE | ID: mdl-36764114

RESUMO

Natural chitosan-based films (CS) were fabricated by changing ingredient corporations between gold nanoparticles (AuNPs), lithium oxide (Li2O), and graphene oxide (GO). A Series of films with different components were obtained. The structural examination is executed by XRD, FTIR, and EDX to analyze crystal structure, chemical bonding, and chemical contents, respectively. The findings illustrated that, the Li2O@CS exhibited the lowest contact angle with 70 ± 4.6°. Scanning Electron Microscopy (SEM) displayd rod-shaped AuNPs with an average length of 0.3 µm and an average width of 90 nm. The refractive index of CS recorded 2.142, while AuNPs/Li2O/GO@CS slightly declined to 2.085. Concerning AuNPs/Li2O/GO@CS, the detected cell viability percentage of normal lung cells among the usage of 156.25 µg/mL is 98.91%, while 9.77 µg/mL achieved 125.78%. Therefore, combining AuNPs, GO and Li2O within the CS matrix results in films of boosted biocompatibility and can be suggested for medical applications.


Assuntos
Quitosana , Nanopartículas Metálicas , Quitosana/química , Ouro/química , Óxidos , Lítio , Sobrevivência Celular , Nanopartículas Metálicas/química
7.
Materials (Basel) ; 15(21)2022 Oct 28.
Artigo em Inglês | MEDLINE | ID: mdl-36363182

RESUMO

In this work, the preparation, characterization, and evaluation of a novel nanocomposite using polyaniline (PANi) functionalized bi-metal oxide ZnO-TiO2 (ZnTiO@PANi) as shielding film for carbon steel (CS)-alloy in acidic chloride solution at 298 K was studied. Different spectroscopic characterization techniques, such as UV-visible spectroscopy, dynamic light scattering (DLS), X-ray photoelectron spectroscopy (XPS), and Fourier transform infrared spectroscopy (FTIR) approaches, as well as other physicochemical methods, such as X-ray diffraction (XRD), high-resolution transmission electron microscopy (HR-TEM), and field emission scanning electron microscope (FESEM), were used to describe the produced nanocomposites. The significance of these films lies in the ZnO-TiO2 nanoparticle's functionalization by polyaniline, a material with high conductivity and electrochemical stability in acidic solutions. The mechanistic findings of the corrosion inhibition method were obtained by the use of electrochemical methods including open-circuit potentials (OCP) vs. time, potentiodynamic polarization (PDP), and electrochemical impedance spectroscopy (EIS). The results indicate that the synthesized ZnTiO@PANi is a powerful acidic corrosion inhibitor, and its inhibition effectiveness is 98.86% in the presence of 100 ppm. Additionally, the charge transfer resistance (Rp) value augmented from 51.8 to 432.7, and 963.7 Ω cm2 when the dose of PANi, and ZnTiO@PANi reached 100 ppm, respectively. The improvement in Rp and inhibition capacity values with an increase in nanocomposite dose is produced by the nanocomposite additives covering a larger portion of the surface, resulting in a decrease in alloy corrosion. By identifying the probable regions for molecule adsorption on the steel substrate, theoretical and computational studies provided significant details regarding the corrosion mitigation mechanism. The possibility of substituting old poisonous small substances with inexpensive and non-hazardous polymeric materials as shielding layers for utilization in the oilfield sectors is an important suggestion made by this research.

8.
Polymers (Basel) ; 14(21)2022 Nov 04.
Artigo em Inglês | MEDLINE | ID: mdl-36365727

RESUMO

Due to their thermal stability characteristics, polymer/composite materials have typically been employed as corrosion inhibitors in a variety of industries, including the maritime, oil, and engineering sectors. Herein, protective films based on binary ZnO-NiO@polyaniline (ZnNiO@PANE) nanocomposite were intended with a respectable yield. The produced nanocomposite was described using a variety of spectroscopic characterization methods, including dynamic light scattering (DLS), ultraviolet-visible spectroscopy (UV-Vis), Fourier-transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS) approaches, in addition to other physicochemical methods, including X-ray powder diffraction (XRD), transmission Electron Microscopy (TEM), field emission scanning electron microscopy (FESEM), and selected area electron diffraction (SAED). By using open-circuit potentials (OCP) vs. time, electrochemical impedance spectroscopic (EIS), and potentiodynamic polarization (PDP) methods, the inhibitory effects of individual PANE and ZnNiO@PANE on the mild steel alloy corrosion in HCl/NaCl solution were assessed. The ZnNiO@PANE composite performed as mixed-type inhibitors, according to PDP findings. PANE polymer and ZnNiO@PANE composite at an optimal dose of 200 mg/L each produced protective abilities of 84.64% and 97.89%, respectively. The Langmuir isotherm model is used to explain the adsorption of ZnNiO@PANE onto MS alloy. DFT calculations showed that the prepared materials' efficiency accurately reflects their ability to contribute electrons, whereas Monte Carlo (MC) simulations showed that the suitability and extent of adsorption of the ZnNiO@PANE molecule at the metal interface determine the materials' corrosion protection process.

9.
Nanomaterials (Basel) ; 12(19)2022 Sep 30.
Artigo em Inglês | MEDLINE | ID: mdl-36234558

RESUMO

In this work, novel phosphate materials based on bimetallic character (Fe and Ni) were introduced by different chemical fabrication methods, the reflux method (FeNiP-R) and the sol-gel technique (FeNiP-S), and evaluated as non-precious electrodes for methanol electrooxidation in KOH electrolytes. The designed FeNiP-R and FeNiP-S samples were investigated using different characterization techniques, namely TEM, SEM, XPS, BET, DLS, and FT-IR, to describe the impact of the fabrication technique on the chemistry, morphology, and surface area. The characterization techniques indicate the successful fabrication of nanoscale-sized particles with higher agglomeration by the sol-gel technique compared with the reflux strategy. After that, the electrochemical efficiency of the fabricated FeNiP-R and FeNiP-S as electrodes for electrocatalytic methanol oxidation was studied through cyclic voltammetry (CV) at different methanol concentrations and scan rates in addition to impedance analysis and chronoamperometric techniques. From electrochemical analyses, a sharp improvement in the obtained current values was observed in both electrodes, FeNiP-R and FeNiP-S. During the MeOH electrooxidation over FeNiP-S, the current value was improved from 0.14 mA/cm2 at 0.402 V to 2.67 mA/cm2 at 0.619 V, which is around 109 times the current density value (0.0243 mA/cm2 at 0.62 V) found in the absence of MeOH. The designed FeNiP-R electrode showed an improved electrocatalytic character compared with FeNiP-S at different methanol concentrations up to 80 mmol/L. The enhancement of the anodic current density and charge transfer resistance indicates the methanol electrooxidation over the designed bimetallic Fe/Ni-phosphates.

10.
Materials (Basel) ; 15(17)2022 Sep 05.
Artigo em Inglês | MEDLINE | ID: mdl-36079556

RESUMO

This work investigates an electrochemical impedance analysis based on synthesized TiO2 nanofibers (NFs) photoanodes, which were fabricated via electrospinning and calcination. The investigated photoanode substrate NFs were studied in terms of physicochemical tools to investigate their morphological character, crystallinity, and chemical contents via scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS), and X-ray diffraction (XRD) analyses. As a result, the studied photoanode substrate NFs were applied to fabricate dye-sensitized solar cells (DSCs), and the electrochemical impedance analysis (EIS) was studied in terms of equivalent circuit fitting and impacts of N-doping, the latter of which was approved via XPS analysis. N-doping has a considerable role in the enhancement of charge transfers, which could be due to the strong interactions between active-site N atoms and the used photosensitizer.

11.
Polymers (Basel) ; 14(18)2022 Sep 12.
Artigo em Inglês | MEDLINE | ID: mdl-36145960

RESUMO

A novel drug delivery system based on carboxymethyl cellulose containing copper oxide at melamine and zinc oxide at melamine framework (CMC-Cu-MEL and CMC-Zn-MEL) was prepared by the hydrothermal route. Synthesized nanocomposites were characterized by FTIR, SEM, and Raman spectroscopy. In addition, transmission electron microscopy (TEM) and selected area electron diffraction (SAED) images were applied to confirm the particle size and diffraction pattern of the prepared nanocomposites. Furthermore, the crystallinity of the synthesized CMC, CMC-Cu-MEL, and CMC-Zn-MEL materials was studied via X-ray diffraction (XRD). Estimating the transport exponent, which discloses the solvent diffusion and chain relaxation processes, and the Ritger-Peppas kinetic model theory were used to control the TC release mechanism from CMC-Cu-MEL and CMC-Zn-MEL. Additionally, the CMC-Cu-MEL and CMC-Zn-MEL containing TC had the highest activity index percents of 99 and 106% against S. aureus and 93 and 99% against E. coli, respectively. The tailored CMC-Cu-MEL and CMC-Zn-MEL for drug delivery systems are expected to be feasible and efficient.

12.
Polymers (Basel) ; 14(15)2022 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-35956592

RESUMO

Corrosion is considered to be the most severe problem facing alloys and metals, one that causes potentially dangerous industrial issues such as the deterioration of buildings and machinery, and corrosion in factory tanks and pipelines in petroleum refineries, leading to limited lifetime and weak efficacy of such systems. In this work, novel CeO2-nanoparticle-loaded carboxymethyl cellulose (CMC) was successfully prepared by using a simple method. The structural configuration of the prepared CeO2-nanoparticle-loaded CMC was investigated by FE-SEM/EDX, TEM, FT-IR, and thermal analyses. The corrosion protection proficiency of uncoated and coated mild steel with CeO2-CMC systems in 1.0 M HCl solutions was studied by EOCP-time, EIS, and PDP tools. Moreover, the relationship between the structure of coating films and their corrosion protection was confirmed by DFT calculation and MC simulation. The obtained findings from the studied methods showed that the prepared CeO2-CMC-coated films reported high corrosion resistance. The protection capacity augmented with ceria presents an increase of up to 3% to achieve 98.4%. DFT calculation and MC simulation confirmed the influence of the chemical construction of coated films on its protection capacity, which was in accordance with the experimental results.

13.
Polymers (Basel) ; 14(13)2022 Jun 22.
Artigo em Inglês | MEDLINE | ID: mdl-35808589

RESUMO

An eco-friendly and a facile route successfully prepared novel cerium oxide nanoparticles functionalized by gelatin. The introduced CeO2@gelatin was investigated in terms of FE-SEM, EDX, TEM, chemical mapping, FT-IR, and (TGA) thermal analyses. These characterization tools indicate the successful synthesis of a material having CeO2 and gelatin as a composite material. The prepared composite CeO2@gelatin was used as an environment-friendly coated film or X60 steel alloys in acidizing oil well medium. Moreover, the effect of CeO2 percent on film composition was investigated. LPR corrosion rate, Eocp-time, EIS, and PDP tools determined the corrosion protection capacity. The CeO2@gelatin composite exhibited high protection capacity compared to pure gelatin; in particular, 5.0% CeO2@gelatin coating film shows the highest protection capacity (98.2%), with long-term anti-corrosive features. The % CeO2@gelatin-coated films formed the protective adsorbed layer on the steel interface by developing a strong bond among nitrogen atoms in the CeO2@gelatin film and the electrode interface. Surface morphology using FESEM measurements confirmed the high efficiency of the fabricated CeO2@gelatin composite on the protection X60 steel alloys. DFT calculations and MC simulations were explored to study the relations between the protection action and the molecular construction of the coated systems, which were in good alignment with the empirical findings.

14.
Malays Orthop J ; 16(1): 112-114, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35519526

RESUMO

Malunion of recurrent fractures in Osteogenesis Imperfecta (OI) patients causes limb length discrepancy and malrotation. These cause added difficulty for OI patients to ambulate. Lengthening with distraction osteogenesis using an external fixator in OI patients is challenging. Acute lengthening with autologous bone graft is a known method in a normal bone but not a known procedure in OI patients. We present two clinic cases of adolescent OI patients with limb length discrepancy and externally rotated lower limb that underwent acute lengthening and rotational correction using a locked intramedullary nail and ipsilateral autologous iliac bone graft. Both patients obtained union and improvement of ambulatory capability without recurrence of fracture within five years of follow-up. Acute lengthening by 2cm and rotational correction with intramedullary nail improved the gait efficiency in the OI patients. Harvesting large amounts of the tricortical iliac bone graft, followed by controlled weight-bearing is a safe procedure.

15.
Sci Rep ; 12(1): 6667, 2022 04 23.
Artigo em Inglês | MEDLINE | ID: mdl-35461338

RESUMO

The current work investigated the preparation of Nano-particles of Co/Zn Al2O4 as a catalyst via co-precipitation method. Several analyses, including BET, XRD, HRTEM, EDX, SEM, and FTIR, were used to characterize it. The analysis revealed that the prepared catalyst had an average surface area of 69.20 m2/g, a cross-sectional area of 16.2 m2/molecule, an average particle size of approximately 28 nm, and a pore size of 0.22 cm3/g. The prepared catalyst was used in a bio fuel synthesis process via thermo-catalytic cracking of waste cooking oil (WCO) in a single step batch reactor. Catalyst loading was tested with different weight percentage of 1.5%, 2%, and 2.5%. The pilot study revealed that the best conditions for optimizing bio jet fuel yield were 400 °C, a catalyst loading of 2%, and a reaction time of 30 min.The optimal cut-off from the distillation process of crude liquid bio fuel product which represents a fraction of bio-jet fuel was in the range from 150 to 240 °C.


Assuntos
Biocombustíveis , Óleos de Plantas , Biocombustíveis/análise , Catálise , Culinária , Projetos Piloto , Zinco
16.
Morphologie ; 106(354): 145-154, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34023214

RESUMO

BACKGROUND: Polycystic ovary syndrome (PCOS) is a multifactorial hormonal disorder accompanied by impairment of endometrial function and structure. Pomegranate is recognized for its role in normalizing the female sex hormones in PCOS with little known about its effect on the accompanying endometrial histological alterations. AIM OF THE WORK: To assess the possible ameliorative role of pomegranate juice extract (PJE) on endometrial injury in a rat model of PCOS. MATERIAL AND METHODS: Forty adult albino rats were equally divided into 4 groups; control, PJE-treated (400mg/kg/day for 3 weeks), letrozole-treated (PCOS) (1mg/kg/day for 3 weeks), and PJE & PCOS groups. Serum Follicle-stimulating hormone (FSH), Luteinizing hormone (LH), testosterone, estradiol, and tissue malondialdehyde (MDA) were assayed. Uterine samples were processed for histological staining with hematoxylin & eosin and Masson's trichrome stains, Ki67 and androgen receptor immunohistochemical staining, and scanning electron microscopy. RESULTS: PCOS group revealed a significant increase in serum FSH, LH, testosterone, estradiol, and tissue MDA. Uterine sections depicted various histological alterations in the endometrium with signs of inflammation. A significant increase in the endometrial collagen fiber content, as well as a significant upregulation in Ki67 and androgen receptor immunohistochemical expression were detected. Scanning electron microscopy showed a significant decrease in the mean number of pinopodes. Concomitant administration of PJE efficiently restored the studied biochemical, histological, and immunohistochemical parameters. CONCLUSION: PJE ameliorated PCOS accompanying endometrial histological alterations through its antioxidant, anti-inflammatory, anti-fibrotic, anti-proliferative, and anti-androgenic effects most probably due to its polyphenols content.


Assuntos
Extratos Vegetais , Síndrome do Ovário Policístico , Punica granatum , Receptores Androgênicos , Androgênios , Animais , Proliferação de Células , Endométrio/metabolismo , Endométrio/patologia , Estradiol , Feminino , Hormônio Foliculoestimulante , Antígeno Ki-67 , Hormônio Luteinizante , Extratos Vegetais/farmacologia , Síndrome do Ovário Policístico/tratamento farmacológico , Síndrome do Ovário Policístico/metabolismo , Punica granatum/química , Ratos , Receptores Androgênicos/metabolismo , Testosterona
17.
Front Plant Sci ; 13: 966377, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36714787

RESUMO

Sugar beet productivity is highly constrained by the root-knot nematode (RKN) Meloidogyne incognita. Eight sugar beet genotypes were screened under greenhouse conditions for their susceptibility to M. incognita according to an adapted quantitative scheme for assignment Canto-Saenz's host suitability (resistance) designations (AQSCS). Besides, the degree of susceptibility or tolerance of the examined genotypes was recorded by the modified host-parasite index (MHPI) scale based on yield performance. In addition, single nucleotide polymorphism (SNP) was also determined. Sugar beet genotypes have been classified into four categories for their susceptibility or tolerance according to the AQSCS scale. The first category, the moderately resistant (MR) group implies only one variety named SVH 2015, which did not support nematode reproduction (RF≤1), and had less root damage (GI≈2). Second, the tolerant group (T) involving Lilly and Halawa KWS supported fairly high nematode reproduction (RF>1) with relatively plant damage (GI≤2). Whereas the susceptible (S) category involved four varieties, FARIDA, Lammia KWS, Polat, and Capella, which supported nematode reproduction factor (RF>1) with high plant damage (GI>2). The fourth category refers to the highly susceptible (HYS) varieties such as Natura KWS that showed (RF≤1) and very high plant damage (GI>2). However, the MHPI scale showed that Lammia KWS variety was shifted from the (S) category to the (T) category. Results revealed significant differences among genotypes regarding disease severity, yield production, and quality traits. The SVH 2015 variety exhibited the lowest disease index values concerning population density with 800/250 cm3 soils, RF=2, root damage/gall index (GI=1.8), gall size (GS=2.3), gall area (GA=3.7), damage index (DI=3.4), susceptibility rate (SR=2.4), and MHP index (MHPI=2.5). However, Lammia KWS showed the highest disease index values regarding population density with 8890/250 cm3 soils, RF= 22.2, GI= 4.8, and SR= 14.1. Meanwhile, Natura KWS the highest GS, GA and MHPI with 7.1, 8 and 20.9, respectively. The lowest DI was achieved by Capella (DI= 6) followed by Lammia KWS (DI= 5.9). For yield production, and quality traits, SVH 2015 exhibited the lowest reductions of sugar yields/beet's root with 11.1%. While Natura KWS had the highest reduction with 79.3%, as well as it showed the highest reduction in quality traits; including sucrose, T.S.S, and purity with 65, 27.3, and 51.9%, respectively. The amino acid alignment and prediction of the DNA sequences revealed the presence of five SNPs among all sugar beet verities.

18.
Molecules ; 26(16)2021 Aug 05.
Artigo em Inglês | MEDLINE | ID: mdl-34443318

RESUMO

In this study, the surface-initiated atom transfer radical polymerization (SI-ATRP) technique and electroless deposition of silver (Ag) were used to prepare a novel multi-functional cotton (Cotton-Ag), possessing both conductive and antibacterial behaviors. It was found that the optimal electroless deposition time was 20 min for a weight gain of 40.4%. The physical and chemical properties of Cotton-Ag were investigated. It was found that Cotton-Ag was conductive and showed much lower electrical resistance, compared to the pristine cotton. The antibacterial properties of Cotton-Ag were also explored, and high antibacterial activity against both Escherichia coli and Staphylococcus aureus was observed.


Assuntos
Antibacterianos/química , Antibacterianos/farmacologia , Fibra de Algodão/análise , Condutividade Elétrica , Prata/química , Prata/farmacologia
19.
J Physiol Pharmacol ; 72(1)2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34099585

RESUMO

The safety and effectiveness of nutricetics suggest that they may offer an alternative to pharmaceutical and surgical therapy for hormone-dependent disorders, such as polycystic ovarian syndrome (PCOS). We investigated the effects of Linum usitatissimum seed oil (LSO) on ovarian functionality, its molecular targets, and the oxidative response in hyperandrogenism-induced polycystic ovary. The composition of LSO has been analyzed using ultra-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UPLC-ESI-MS). A well-established PCOS rat model orally administered with letrozole daily for 21 days was used to investigate the effect of LSO at doses of 1 and 2 mL/kg body weight for 28 days. The effect on hormonal profile and antioxidant status, histopathology (cell proliferation), and the expression ratio of the steroidogenic acute regulatory protein (StAR) and Cyp11A1 gene were evaluated. LSO exerted beneficial effects on PCOS rat models via restoring glutathione (GSH), malondialdehyde (MDA), beta subunit subunit luteinizing hormone (LH), testosterone levels, and histopathological scoring. Furthermore, LSO reversed the elevated StAR and Cyp11A1 genes in the PCOS rat model. This study demonstrated the molecular and cellular mechanisms of the beneficial effect of LSO against the reproductive and metabolic disorders of PCOS.


Assuntos
Linho/química , Óleo de Semente do Linho/farmacologia , Síndrome do Ovário Policístico/tratamento farmacológico , Animais , Antioxidantes/metabolismo , Enzima de Clivagem da Cadeia Lateral do Colesterol/genética , Cromatografia Líquida de Alta Pressão , Modelos Animais de Doenças , Relação Dose-Resposta a Droga , Regulação para Baixo/efeitos dos fármacos , Feminino , Letrozol , Óleo de Semente do Linho/administração & dosagem , Óleo de Semente do Linho/química , Fosfoproteínas/genética , Síndrome do Ovário Policístico/genética , Síndrome do Ovário Policístico/fisiopatologia , RNA Mensageiro/metabolismo , Ratos , Ratos Wistar , Espectrometria de Massas por Ionização por Electrospray
20.
Membranes (Basel) ; 11(3)2021 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-33808518

RESUMO

Pressure-driven membrane processes, i [...].

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