RESUMO
PURPOSE: Evaluate therapeutic results of transcatheter segmental hepatic artery chemo-oily-embolization (segmental TAE) against advanced hepatocellular carcinomas (HCC) accompanied by portal tumor thrombus (PTT). METHODS: Segmental TAE was performed in nine patients with hepatic cirrhosis and advanced HCCs accompanied by PTT. Four subsegmental portal branches were obstructed by PTT in three patients, and two were obstructed in the remaining six patients. TAE was performed into the targeted segmental hepatic artery followed by embolization with gelatin sponge particles. RESULTS: In one patient undergoing subsequent resection, a marked anticancer effect on the PTT was demonstrated histologically. In the eight other patients who did not undergo subsequent resection, the cumulative survival rates were 67% at 6 months, 44% at 1 year, and 22% at 2 years. No serious complications were noted. CONCLUSIONS: This therapeutic approach is thought to be a useful treatment for HCC with PTT, because it reinforces anticancer effects and can be performed more safely than conventional transcatheter arterial embolization.
Assuntos
Carcinoma Hepatocelular/terapia , Quimioembolização Terapêutica/métodos , Neoplasias Hepáticas/terapia , Células Neoplásicas Circulantes/patologia , Veia Porta , Neoplasias Vasculares/terapia , Idoso , Antibióticos Antineoplásicos/administração & dosagem , Protocolos de Quimioterapia Combinada Antineoplásica/administração & dosagem , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Carcinoma Hepatocelular/patologia , Carcinoma Hepatocelular/cirurgia , Terapia Combinada , Epirubicina/administração & dosagem , Feminino , Seguimentos , Gelatina/administração & dosagem , Hepatectomia , Artéria Hepática , Humanos , Injeções Intralesionais , Óleo Iodado/administração & dosagem , Neoplasias Hepáticas/patologia , Neoplasias Hepáticas/cirurgia , Masculino , Pessoa de Meia-Idade , Mitomicina/administração & dosagem , Veia Porta/patologia , Indução de Remissão , Taxa de Sobrevida , Neoplasias Vasculares/patologiaRESUMO
We have experienced three adult intussusception cases with colorectal cancer. In all three cases CT studies were performed prior to administering a barium enema, where we could make the exact diagnosis of the lesions in both the plain and the contrast studies. In the CT studies, the intussusception lesions showed the characteristic eccentric layered pattern. It was difficult to distinguish the tumors from the edematous intestinal walls at the proceeding portion in two cases. While in one case, the proceeding portion (the tumor itself) was pointed out as the enhanced soft tissue density mass of layered pattern with the irregular margins.
Assuntos
Neoplasias Colorretais/diagnóstico por imagem , Intussuscepção/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Idoso , Neoplasias Colorretais/complicações , Feminino , Humanos , Intussuscepção/complicações , Masculino , Pessoa de Meia-IdadeRESUMO
An investigation was conducted into the adverse reactions, especially delayed reactions, of non-ionic contrast media. Out of a total number of 3,411 people treated, there were 45 cases (1.32%) in which adverse reactions were observed, and of these 45 cases, 14 cases (0.41% of the total number) showed delayed adverse reactions. Of the aforesaid 14 patients with delayed adverse reactions, all of them developed skin eruptions, but no seriously adverse effects were eventually observed.
