Psychological Reactions, Social Support, and Coping Styles in Pakistani Female Burn Survivors.

This study was aimed to explore the level of psychological distress and posttraumatic stress among female burn survivors in Pakistan. It was also intended to study the kind of social support available to these burn survivors in a society where women right violation is common. The sample consisted of 35 female burn victims selected from two hospitals. General Health Questionnaire, posttraumatic stress disorder Checklist-Specific, and Social Support Scale were used to measure study variables in addition to a short open-ended questionnaire to identify coping strategies of these burn survivors. Consistent with the hypothesis, results found a high level of psychological reaction among female burn survivors. About one-quarter of the sample (23%) presented severe symptoms of psychological distress whereas 20% of the sample reported to experience severe posttraumatic stress disorder symptoms. There was a significant inverse relationship between psychological reactions and social support as hypothesized. Majority of female burn victims found to use emotion-focused coping (EFC) mainly including prayers, emotional discourse, and using drugs. The findings of the study would be helpful to plastic surgeons, dermatologists, psychologists, and social workers to understand the patient's psychological reactions, their copying styles, and the role of social support in the rehabilitation program for these survivors.

Significance of prostate specific antigen in prostate cancer patients and in non cancerous prostatic disease patients.

OBJECTIVE: To evaluate the significance of prostate specific antigent (PSA) and scan in prostate cancer patients and in non cancerous prostatic disease patients. METHODS: The study was carried out in Radioimmunoassay (RIA) lab, KIRAN Hospital, Karachi during 2002 to 2006. A total of 149 serum samples were collected in which 93 samples were biopsy positive prostate cancer patients referred to KIRAN hospital for treatment. The other 56 samples were collected from patients having other prostatic diseases and advised PSA tests by physicians and urologists from 'The Lab' Karachi. The PSA (total) was measured by immunoradiometric assay (IRMA) in which two monoclonal antibodies against two different epitopes of PSA molecules were used. The results were correlated with bone scan and age of the patients. RESULTS: A total of 149 patient samples were analyzed in which 93 were from biopsy positive prostate cancer patients and 56 from patients having other prostatic diseases. Out of 93 prostate cancer patients sample, 74 (79.6%) had elevated PSA level (>4 ng/ml) and 19 (20.4%) had PSA within normal range (<4 ng/ml). Among 74 elevated PSA level cases, 48 (64.8%) had a positive bone scan and 26 (35.2%) had negative bone scan. Minimum age recorded was 40 years (Mean age 66.4 +/- 9.1 years). In fifty six (56) serum samples which were collected from 'The Lab' and having other prostatic diseases, 49 (87.5%) had PSA within normal range (< or =4 ng/ml). CONCLUSION: Prostate specific antigen has a significant role for the diagnosis of prostate cancer (and has a significant correlation with bone scan). Immunoradiometric assay has a sensitivity of 79.5% and specificity of 87.5% for prostate cancer.