Assuntos
Cateterismo/instrumentação , Doenças Nasofaríngeas/terapia , Idoso , Carcinoma , Terapia Combinada , Constrição Patológica/etiologia , Constrição Patológica/terapia , Endoscopia , Desenho de Equipamento , Seguimentos , Humanos , Masculino , Carcinoma Nasofaríngeo , Doenças Nasofaríngeas/etiologia , Neoplasias Nasofaríngeas/complicações , Neoplasias Nasofaríngeas/terapiaRESUMO
In the 3 strains of Aspergillus nidulans used, BC reduced survival most and 4HMB least. Similar trends were found when the effect on gene conversion was studied in a diploid strain and point mutation was scored in a haploid strain. None of the compounds had any effect on mitotic segregation.
Assuntos
Aspergillus nidulans/efeitos dos fármacos , Compostos de Benzil/farmacologia , Compostos de Bifenilo/farmacologia , Mutagênicos/farmacologia , Mutação , Testes de Mutagenicidade , Relação Estrutura-AtividadeRESUMO
A genetically marked heterozygous diploid of Aspergillus nidulans was synthesized and the feasibility of using this system for the simultaneous estimation of radio-induced mitotic crossing-over and non-disjunction has been investigated. In the case of the latter, serious experimental problems have been encountered. Nevertheless, induction curves for non-disjunction with 15-MeV electrons, 50-kVp X-rays, beta-particles and alpha-particles are presented showing an increase in non-disjunction with increasing LET.
