1.
Bioorg Med Chem Lett
; 15(8): 2011-4, 2005 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15808458
RESUMO
Several analogues of UK-2A, a novel antifungal antibiotic isolated from Streptomyces sp. 517-02, were semi-synthesized for structure-activity studies. In vitro antifungal activities of these compounds against Saccharomyces cerevisiae IFO 0203 were evaluated by the conventional paper disk method. Several derivatives exhibited growth inhibitory activity similar to UK-2A.