[Specific parameters of blood lipid spectrum in adolescents with various forms of hypertension].

Lipid metabolic parameters were studied in 45 adolescents aged 14-17 years with labile or persistent hypertension. The concentration of atherogenic lipid fractions, such as very low-density lipoproteins and triglycerides was found to be significantly higher in the study group than that in the control groups. In the hypertension groups, the atherogeneity index was statistically more significant that in the controls. At the early stage of the pathological process, increased atherogenic fractions are a risk factor of hypertension in adolescents.

[Cardiac arrhythmias during an elective cholecystectomy].

The paper presents systemized literature data on cardiac arrhythmias (CA) associated with cholecystectomies. The authors present an analysis of CA in 101 patients with chronic calculous cholecystitis (CCC), registered before, during and after an elective cholecystectomy (the surgery was performed either through laparotomy or using endovideosurgical technique). The study revealed that cholecystectomy, especially laparatomic one, bore an arrythmogenic effect. Additional predictors of dangerous CA associated with surgical treatment of CCC, were presence of sinus tachycardia, bradycardia, ciliary arrhythmia, changes in the variability of heart rate, and preoperative heart enlargement.

[Sanitary assessment of radon hazards in residential buildings]. / Gigienicheskaia otsenka opasnosti radona v zhilykh pomeshcheniiakh.

The authors have constructed models including that of dose-effect of the content of decay products, that of the volumetric activity of radon in the apartments, and that of biological human responses. They have found specific features of female reproduction dysfunction, perinatal, general, and cancer morbidity and mortality. The maximum ineffective radon concentration upon chronic exposure has been established by using dosage simulation of the frequency of genetic disorders (small malformations).

[Normalization of intestinal microflora and the general condition of mice of the JCR line as affected by Bifidobacterium concentrate]. / Normalizatsiia kishechnoi mikroflory i obshchego sostoianiia myshei linii JCR pod vliianiem kontsentrata bifidobakterii.

It was shown experimentally that the use of liquid Bifidobacterium concentrate (B. bifidum 791 and B. adolescentis MS-42) led to normalization of microflora in mice which resulted in the improvement of the animal general state: increase of body weight, lower death rate, decreased late embryonic mortality, better hair growth.

[Automated diagnosis of vibration disease]. / Avtomatizirovannaia diagnostika vibratsionnoi bolezni.

Based on a multidimensional discriminant analysis of the clinical and physiological characteristics derived as a result of examination of 593 miners, classification functions were plotted, allowing the diagnosis of vibratory disease in the automatic mode by means of mathematic computations. Functional indicators of skin sensitivity, particularly vibratory, dynamometry, rheovasography and thermography of the hand and fingers, a "white spot" symptom, and characteristics derived on a mathematic analysis of heart rhythm were established to be informative for automated diagnosis. The diagnosis was found to be more accurate in case of using a two-stage variant of the discriminant analysis where the differentiation is first made between healthy workers and workers with a pathology, followed by the discrimination of the preclinical and clinical phase of the disease. The automated diagnostic system is demonstrated to compare very favourably with the conventional method of diagnosis.

[Estimation of parental resistance in evaluating the effect of chemical substances on children's health]. / Ob uchete rezistentnosti organizma roditelei pri otsenke vliianiia khimicheskikh veshchestv na zdorov'e detei.

Proceeding from the experimental study carried out on the model of aniline methemoglobinemia, it was shown that the animals with low aniline-related resistance also had aniline low-resistant posterity during two following generations and vice versa high-resistant animals had the more aniline-resistant posterity. It was determined both by methemoglobin levels and by the number of animals with different methemoglobin levels. According to the degree of aniline-induced methemoglobinemia the correlation among three generations of animals was established.

[Effect of chemical substances on the resistance of experimental animals to influenza virus]. / Vliianie khimicheskikh veshchestv na soprotivliaemost' eksperimental'nykh zhivotnykh k virusu grippa.

An experimental evaluation of the impact of a number of chemical compounds toxicologically attributed to different hazardous classes on animal resistibility to influenza virus showed that resistibility dependence on the dose and effect duration had a nonlinear character. There was no complete correlation of a hazardous class of chemical substances and their impact on body resistibility to respiratory infections.

[Effect of long-wave ultraviolet radiation on the cyclophosphamide-induced frequency of chromosome aberrations in mouse bone marrow cells]. / Vliianie dlinnovolnovogo ul'trafioletovogo izlucheniia na indutsirovannuiu tsiklofosfamidom chastotu khromosomnykh aberatsii v kletkakh kostnogo mozga myshei.

The paper deals with the influence of 1-month pretreatment of mice with different regimes of long-wave UV-radiation on spontaneous and cyclophosphamide (CP) induced levels of chromosome aberrations in the bone marrow cells. The level of aberrant cells in the bone marrow of control and CP treated mice was not changed by the suberythematous dose (0.5 of the erythematous dose) of UV-radiation. The mice pretreatment with 3 erythematous doses of UV-radiation significantly increased spontaneous and CP induced level of cells with chromosome aberrations as compared with that in UV-unexposed mice.