[Results of skin tests with pollen extracts of fruit trees in patients with pollen allergy]. / Hauttestergebnisse mit Obstblütenpollenextrakten bei Frühblüher-Pollinotikern.

As there have recently been increasing publications on the correlation between tree pollen allergy and fruit allergy, we asked ourselves wether this might be caused by the parallel pollen times of Fagales trees and Rosales trees in our Central European climate. Accordingly, we tested 92 patients positively suffering from Fagales tree pollen allergy with the following Rosales tree pollen extracts: apple, cherry, plum, apricote, almande. 16 out of these patients showed reactions to Fagales pollen but not to Rosales pollen. All the other 76 patients revealed reactions to both the tested pollen extracts. Since these results show our thesis to be false, we have to assume a related (minor) antigen of both tree pollen groups.

[Therapy of rosacea with bifonazole cream--practical experiences over a 2-year period]. / Rosaceatherapie mit Bifonazol-Creme--praktische Erfahrungen über 2-Jahre.

In our first comparative study from 1981/82 on the local therapy of rosacea with imidazole derivates (2) bifonazole cream showed the better results. Since this time we collected experiences with other 87 rosacea patients on this therapy and its variations. We divided these patients into three groups: a) rosacea teleangiektatica, b) rosacea papulopustulosa, c) rosacea ekzematosa. The therapeutical results with 0.1-0.5% bifonazole cream diluted in Ungt. emulsific. aquos., with the 1% bifonazole cream and with the combined bifonazole-metronidazole therapy are reported. Without several of the patients with rosacea ekzematosa we had moderate to excellent results with a long time intervall therapy.

[Treatment of moderately severe virilism of women with Diane and Androcur 10]. / Die Behandlung mittelschwerer Virilisierungs-erscheinungen der Frau mit Diane und Androcur 10.

We report on 20 female patients suffering from acne, seborrhea, hirsutism, and androgenic alopecia during the years 1980-1982 who have been treated with 1 tablet of Androcur 10 (10 mg cyproteronacetate) daily, in the first 15 days applied together with Diane (0,05 mg ethinylestradiol and 2 mg cyproteronacetate). The results achieved after 2 years show an improvement of acne in 80 per cent of the cases, of seborrhea in 95 per cent, and of both hirsutism and androgenic alopecia in 45 per cent each. So this therapy takes its important place between the therapy with Diane alone and the usual supplementary dosis of 50 mg cyproteronacetate (Androcur) daily.

[Local treatment of rosacea with imidazole derivatives]. / Externtherapie der Rosacea mit Imidazolderivaten.

Reports about a good effectiveness of systemic therapy of papular rosacea with metronidazole stimulated us to investigate the value of a local treatment 1) with metronidazole mixed in Ungt. emulsific. aquosum, 2) some other available imidazole-derivative-cremes, 3) a new agent bifonazole. The last substance had a better effectiveness than the others, but the results with all these preparations were well enough to recommend them even in lower concentrations for local treatment of papular rosacea.