[Obstetric management of Klippel-Trenaunay syndrome. A case report]. / Managementul obstetrical in cazul unei paciente cu sindrom Klippel - Trenaunay. Prezentare de caz.

UNLABELLED: A rare case of pregnancy in a patient with Klippel-Trenaunay-Weber syndrome is described. The arterio-venous anomalies in this patient originally occurred in her left leg. Her pregnancy was uneventful. A Cesarean section was performed at term. There were no signs of intravascular coagulation or cardiac decompensation. Prophylactic anticoagulant treatment was given during the 3rd trimester and into the early puerperium The clinical course and the risks of a pregnancy with this condition are discussed. CONCLUSION: Klippel-Trenaunay syndrome was once thought to be a contraindication to pregnancy. With careful management, successful pregnancies can be achieved.

[FISH technique in aneuplodies prenatal diagnosis]. / Importanta tehnicii FISH in diagnosticul prenatal al aneuploidiilor.

UNLABELLED: Chromosomal disorders are severe and affect 0.9% of the newborns. In these conditions, prenatal diagnosis should be compulsory in every public medical system. MATERIAL AND METHOD: Our study is a retrospective analysis of pregnant women investigated by amniocentesis and FISH technique. RESULTS: We analyzed 233 samples collected between 2004 and 2007 at Iasi "Cuza-Voda" Obstetrics and Gynecology Hospital. The majority of cases were investigated between 16 and 24 weeks of pregnancy. Thirty-eight abnormal cases (16.30%) were identified: 17 cases with 21 trisomy, 16 cases with 18 trisomy, 3 cases with X monosomy, and 2 cases with 13 trisomy. The main reasons for amniocentesis were: advanced maternal age (12.5% abnormal cases) ultrasound abnormalities (26.15% abnormal cases), and biochemical abnormalities (7.14% abnormal cases). CONCLUSION: Our data are in agreement with other studies, and support our results.

[Congenital oropharyngeal tumors in the newborn: problems in team diagnosis and treatment]. / Tumori congenitale cu localizare orofaringiana la nou nascut: probleme de diagnostic si tratament în echipa.

There are a great variety of lesions of oral cavity which may require surgical intervention in neonatal period. The differential diagnoses include tumors (malignant, teratoma, cystic hygroma, lymphangioma, hemangioma), congenital epulis, dermoid cysts, ranula. Congenital epulis of the newborn is a rare tumour which is usually benign. Epulis is also known as a congenital gingival granular cell tumour because of its histological features. Female babies are affected 8-10 times more often than males. Epulis is located on the maxillary ridge twice as often as on the mandible, mostly as single tumours but rarely as multiple tumours. The histogenesis of the tumour is unknown. Spontaneous regression of congenital epulis has been reported in a few cases. However, surgical excision is generally indicated due to interference with feeding or respiration. Recurrence of the tumour after surgery has not been reported yet. We report two cases of congenital epulis, one in 2 hour female neonate and one in a 7 days male neonate. In spite of the rarity of this pathology, the interval between presentation in this two cases was ten days. In one case it was an antenatal diagnosis by ultrasonography, in the other it was associated a genital anomalies (hypospadias). The treatment was surgical excision. The intra- and postoperative course was uneventful.